Day July 30, 2024

Schematic diagram of esophageal cancer cell identification research process. Credit: GE Dianlong A research team led by Prof. Chu Yannan from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences adopted a methionine regulation strategy and found…

An investigation, which examined 1,880 Asian American or Pacific Islander youth who died by suicide during their first two decades, found that the suicide rate for males increased by 72%, and by 125% for females. Suicide rates among males peaked…

Primary and secondary metabolic outcome measures. a, Geometric ratio of intervention (ustekinumab) over control (placebo) over 52?weeks. b, Adjusted AUC C-peptide over 52?weeks by treatment group. c, HbA1c over 52?weeks by treatment group. d, Mean daily exogenous insulin use adjusted…

Credit: Immunity (2024). DOI: 10.1016 Infecting volunteers with malaria reveals why some get sick and others don’t—and points to ways to induce stronger immunity through vaccination. A “human challenge” study—purposefully infecting volunteers with malaria—has revealed crucial insights into how new,…

Age specific rate of deaths from non-melanoma skin cancer in Australia over the last 20 years; collated from Australian Bureau of Statistics data. Credit: Pathology (2024). DOI: 10.1016 Deaths from non-melanoma skin cancers have almost doubled in Australia this millennium—and…

The COVID-19 pandemic brought many issues in health care to light, including the issues of scientific integrity; decision making in the face of scarce or conflicting data; and rapidly-changing guidance that raised and resulted in dis- and misinformation. These issues…

University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs. The UVA researchers, led by Jie Sun, Ph.D., found that…

Credit: Mark James Schornak. In a study published in JAMA Neurology co-authored by Vibhor Krishna, MD, associate professor of neurosurgery at the UNC School of Medicine, researchers found that a staged bilateral focused ultrasound treatment for essential tremor is safe…

Researchers at the National Institutes of Health (NIH) found that rates of preteen suicide (ages 8–12) have been increasing by approximately 8% annually since 2008. The study appears in the journal JAMA Network Open. These increases were most pronounced among…

Three out of five youth who died by suicide in the U.S. did not have a prior mental health diagnosis, signaling missed opportunities to identify children and adolescents for suicide prevention strategies, including therapy or medications to treat depression. This…

Representative examples of immunohistochemical (IHC) staining of AF1q in gastric adenocarcinoma. Samples with (A) enhanced AF1q expression versus samples with (B) hematoxylin–eosin staining of patients that underwent surgery. Scale bar 100 ?m. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-67058-x Surgical removal…

Key findings in the study, including the dynamic pre-metastatic alterations of lymph nodes, the responsible regulatory mechanisms, and lymph node targeting strategies. Credit: Research (2024). DOI: 10.34133 Metastasis has always been enemy number one in malignant tumors, as it is…

Policy reform is urgently needed to assist older adults who live in southern U.S. cities and who experience higher-than-expected heat-related health issues if they don’t have adequate access to air conditioning, according to a new study by University of Waterloo…

New Zealand’s health system is grappling with a severe workforce shortage. Media reports frequently highlight individuals and families being unable to access timely health care, exacerbated by a shortage of general practitioners (GPs) and overflowing emergency departments. But one potential…

At least 38 people, most of them children and teenagers, have died since early June 2024 in the worst outbreak of Chandipura virus in India in over 20 years. This rod-shaped pathogen is a member of the rabies virus family…

Biomarker Rate of Change per Decade From Midlife to Late Life: The Atherosclerosis Risk in Communities Study, 1993-2019. Credit: JAMA (2024). DOI: 10.1001 Before the advent of extensive research, Alzheimer’s disease was only confidently diagnosed postmortem when medical professionals could…

Effect size and significance of longitudinal changes in cortical microstructure and macrostructure. (A) Standardized beta coefficients of change are shown for each parcel and separately for cortical mean diffusivity and cortical thickness, with warmer color and positive effect size indicating…

Colorectal cancer often spreads to the liver, and for some patients, surgical removal of their liver tumors is not an option. A new study led by researchers at the Wilmot Cancer Institute and University of Rochester Medical Center (URMC) shows…

A study has found that a subset of a special type of white blood cells called monocytes could be the key to regrowing blood vessels in the legs of patients with chronic limb-threatening limb ischemia (CLTI). Over the course of…

Overground robot-assisted gait training (RAGT) using a wearable robot improves gross motor function and gait pattern in children with cerebral palsy (CP), according to a study published online July 22 in JAMA Network Open. Ja Young Choi, M.D., Ph.D., from…

An image from the study, showing the areas of the brain affected by Alzheimer’s disease (yellow) found when using real data and when using synthetic data generated by several methods. As you can see, the “ours” images are much more…

FASN inhibition with TVB-2640 impairs spheroid outgrowth in TNBC BM cell lines. Credit: npj Breast Cancer (2024). DOI: 10.1038/s41523-024-00656-0 A new study from the University of Michigan Health Rogel Cancer Center finds that giving a fatty acid inhibitor alongside chemotherapy…

How the assessment of cancer risk could be improved in patients with non-specific symptoms by including information from common blood test results. Credit: Meena Rafiq (CC-BY 4.0, creativecommons.org) The results of routine blood tests could be used to speed up…

Four people who were potentially exposed to hepatitis B and C and HIV during surgeries at a Portland-area hospital have filed a class action lawsuit against Providence, the medical facility and an anesthesiology group claiming their negligence has caused pain,…

Credit: Cancer Cell (2024). DOI: 10.1016 A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to…