Day August 13, 2024

A surging mpox outbreak in Africa, which was declared an emergency by the continent’s health agency on Tuesday, is being driven by a new, more transmissible strain of the virus. The Africa Centres for Disease Control and Prevention (Africa CDC)…

The advantages of the DDSP framework: (a) Our strategy is to make the model domain-agnostic by exposing it to numerous diverse distributions while preserving semantic information in both source and target domains, rather than explicitly teaching it to generate images…

Credit: Cell (2024). DOI: 10.1016 Two studies published in the latest issue of the journal Cell by University of Pittsburgh researchers uncover how immunotherapies targeting the immune checkpoints PD1 and LAG3 work together to activate immune responses. The findings shed…

A new study provides important insights into the pharmacokinetics and safety of intravenous remdesivir in treating the SARS-CoV-2 coronavirus in pregnant women. Remdesivir is an antiviral medication and is used to treat certain patients with COVID-19 who are either hospitalized…

New research has taken a significant step in terms of research and care for acromegaly, a rare disease caused by an excess of growth hormone secretion, which occurs in over 99% of cases due to a generally benign pituitary tumor.…

A research team led by Prof. Li Lei and Prof. Liu Chang from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) has revealed the significant systemic health impact of microplastic (MP) exposure, using the…

by KeAi Communications Co. Influences of treatments on skin hydration indexes, including water content (A) and Transepidermal water loss (TEWL) of volunteers (B) *: Intra-group significance difference, P <0.05;#:Inter-group significance difference, P < 0.05. Credit: Shan Lu, et al With…

Schematic overview of the study design. A multi-omics cohort comprising 316 patients of breast cancer with mammography data. The cohort was stratified according to calcification features. Comparative analyses were conducted across clinicopathological characteristics, multi-omics dimensions, and precision therapeutic strategies. Credit:…

A study involving 22 Parkinson’s disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% and the…

Feeling that your life lacks purpose and that there are few opportunities for personal growth in older age may precede the development of mild cognitive impairment (MCI), a frequent precursor of dementia, suggests research published online in the Journal of…

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and City University of New York suggests that the cognitive difficulties associated with childhood maltreatment, and particularly neglect, have been grossly underestimated in previous studies.…

Despite being home to some of the world’s most dangerous animals, Australia has led the English-speaking world in life expectancy for the last three decades. As for other high-income Anglophone countries, the Irish saw the largest gains in life expectancy,…

A study published in the International Journal of Gynecological Cancer found that the UK’s protocol for picking up early-stage disease in women with high grade serous ovarian cancer—the most common, aggressive, and lethal form of the disease—is an effective way…

Higher intake of heme iron, the type found in red meat and other animal products—as opposed to non-heme iron, found mostly in plant-based foods—was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led…

Pregnancies exposed to buprenorphine combined with naloxone have similar or more favorable neonatal and maternal outcomes as those exposed to buprenorphine alone, according to a study published online Aug. 12 in the Journal of the American Medical Association. Loreen Straub,…

Eating a healthy diet that dampens inflammation in the body could lower your odds for dementia, especially if you already have heart risk factors, a new Swedish study shows. So-called anti-inflammatory diets focus on foods like vegetables, fruits, whole grains,…

An experimental drug based on ancient Chinese herbal medicine can help ease the toxic side effects of chemotherapy and radiation therapy in cancer patients, the results of a small new trial results suggest. A small group of 24 patients experienced…

Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) among patients with type 2 diabetes…

In recent weeks, Dallas has seen an increase in reported cases of COVID-19 and increased levels of the virus in wastewater. The spread is part of an annual summer wave, according to doctors and officials, and there are many ways…

In a national Medicare Advantage (MA) plan, the prevalence of homebound is 22 percent, and homebound status is independently associated with increased health service use and mortality, according to a study published online Aug. 13 in the Annals of Internal…

Jonnae Thompson has felt for a long time that her dark brown skin and natural hair have made finding work in Hollywood especially hard. “It’s like this negative connotation,” said the 37-year-old actress, singer, and stand-up comedian, who said she…

On May 13, Sen. Bernie Sanders, I-Vt., published an open letter to Novo Nordisk on the front page of a leading Danish newspaper, urging the hometown company to live up to its altruistic standards by lowering U.S. prices for its…

New Curtin University-led research has revealed that about 0.5%, or approximately 260, suicide deaths in Australia over a two-decade period were correlated with unusually higher temperatures caused by climate change. The increased risk was observed among men aged 55 and…

For years, the question of whether to take medication to lower high blood pressure had been partly answered by a tool that calculated someone’s 10-year risk of having a heart attack or stroke. But new equations, which take into account…

Cholera risk prediction maps for Matlab, Bangladesh from March to November 2021. Researchers used imagery, based on satellite data from NASA, to create the risk forecasts for the application. Cholera risk is measured on a scale of 0 (low cholera…

In an editorial published in Nutrition Bulletin, the group of obesity management professionals acknowledge the promise of the new generation of weight-loss drugs to change the management of obesity and allow more people to achieve their health goals. But they…

One of my grandmother’s favorite things to cook was cold pressed ox tongue, though it’s a tradition that I don’t really feel the need to continue. Have you ever seen one? Not only is it colossal, but requires a lot…

Alarmed by the surge in mpox cases in Africa, the WHO is meeting to decide whether to trigger its highest alert level over the mpox outbreak sweeping through several African countries. This move comes after a virulent strain of the…

Box plot of variance in FEV1/FVC explained by the PRS for airflow limitation across the lifespan. Credit: eClinicalMedicine (2024). DOI: 10.1016 Certain genetic variants that have previously been linked to the lung disease COPD can explain reduced lung function already…

A researcher demonstrates how a camera captures images of the tongue and analyzes it for disease. Credit: Middle Technical University A computer algorithm has achieved 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The…

Barriers to meeting fluid intake guidelines (N = 137). Credit: PLOS Digital Health (2024). DOI: 10.1371 Maternal under-hydration during pregnancy is associated with a range of negative birth outcomes, including low levels of adequate amniotic fluid and plasma, disrupted fetal…

It’s been a sweltering summer for much of the United States, and a new poll finds many people can recognize the signs of heat sickness if it strikes them or someone else. However, many more don’t know crucial information that…

Representative chest low-dose CT images show lung nodules (arrows) and were included in the study. (A) A solid lung nodule, 82 mm3, in a 77-year-old male participant. (B) A clinically relevant nodule, 174 mm3, in a 55-year-old female participant. (C)…

Mosquito saliva is known to play a significant role in the transmission of viruses such as yellow fever, Zika, dengue, and chikungunya, yet many of its functions have yet to be understood. In a new study, researchers revealed that a…

A University of Sydney study has found that Australian government emergency cash payments, like JobKeeper, significantly helped young adults with pre-existing mental health disorders during the pandemic. Its findings can be built on to inform future crisis support plans about…

Origami-inspired soft robotic electrode array that can be deployed on the brain surface for minimally invasive surgical neural mapping. Credit: Lawrence Coles (University of Cambridge) A research team led by the University of Oxford and the University of Cambridge have…

Examples of histology slides corresponding to modified Ashcroft scores 0–4, for H&E (top) and Masson’s trichrome (bottom) staining. Viewed at 100?×?total magnification. Scale bar?=?200 microns. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-66390-6 Researchers have established a suite of parameters that can…

The model of sleep homeostasis regulation proposed in this study. Prolonged wakefulness activates CaMKII in PV-expressing neurons. The activated CaMKII then activates PV-expressing neurons, leading to rebound sleep. Credit: Department of Systems Pharmacology, Graduate School of Medicine, UTokyo Professor Hiroki…

De novo mutation rates in ADHD versus control subjects. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-50247-7 Rare genetic changes that are spontaneous—and not inherited from parents—may contribute to the underpinnings of attention-deficit/hyperactivity disorder (ADHD), according to a new study from Yale…

The African Union’s health watchdog on Tuesday declared a public health emergency over the growing mpox outbreak on the continent, saying the move is a “clarion call for action”. The outbreak has swept through several African countries, particularly the Democratic…