Day September 16, 2024

How cells generate heat by burning calories

Images of mitochondria in brown adipose tissue using electron microscopy. Brown fat cells are particularly rich in mitochondria, the power plants where cellular respiration takes place. Credit: Alexander Bartelt Special fat cells known as brown adipocytes help maintain body temperature…

A new framework for neurodiversity and mental health

Representation of the proposed neurodevelopmental spectrum alongside dimensions currently in transdiagnostic frameworks. Credit: World Psychiatry (2024). DOI: 10.1002 A study published in World Psychiatry challenges the traditional approach to diagnosing neurodivergent conditions (also known as “neurodevelopmental disorders” in the medical…

Dual maps discovered in the brain

As a rat plans to move from a start position to a target, it can consider the location of the target in “world” coordinates (shown as the target in relation to the reward port with blue vectors) or in “self”…

Preventing heart injury caused by anticancer drugs

Mechanism of remote ischemic conditioning in preventing cardiotoxicity caused by anthracycline-based chemotherapy in patients with lymphoma. Credit: CNIC The RESILIENCE clinical trial has been designed to explore the effectiveness and safety of remote ischemic conditioning (RIC) used to prevent the…

Mucin gel may help disk herniation patients after surgery

The in situ gelling Muc-gels intervention following discectomy prevent intervertebral disc degeneration. The introduction of “clickable” functionality onto mucins are achieved by reacting amine-tetrazine (Tz) or amine-norbornene (Nb) with activated carboxylic groups found in mucins. Credit: Advanced Science (2024). DOI:…

Researchers discover new blood group system

The discovery of a new blood group, MAL, has solved a 50-year-old mystery. Researchers from NHS Blood and Transplant (Bristol), NHSBT’s International Blood Group Reference Laboratory (IBGRL) and the University of Bristol identified the genetic background of the previously known…

Reprogramming cancer cells to attack themselves

cDC1 reprogramming progresses in human cancer spheroids. Credit: Science (2024). DOI: 10.1126 A team of health and medical researchers affiliated with a host of institutions across Sweden has tested the possibility of reprogramming cancer cells into cDC1 cells as a…

Monoclonal antibodies offer hope for tackling antimicrobial resistance

Antibody sequence repertoire analysis from OMV-immunized Kymouse platform mice. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52357-8 Monoclonal antibodies—treatments developed by cloning a cell that makes an antibody—could help provide an answer to the growing problem of antimicrobial resistance, say scientists. A…