Day August 27, 2025

Schematic illustration of composites fabrication procedures for bone regeneration with metabolic effect and involved signaling pathways. Credit: Science Advances (2025). DOI: 10.1126 For most broken bones, bone cells regrow on their own while patients wear a cast or brace to…

Russia’s invasion of Ukraine has killed tens of thousands of Ukrainian soldiers and civilians, and injured hundreds of thousands more. But the war has also taken a less visible toll, with millions suffering from acute PTSD. Now a study co-authored…

Researchers in the Clinical Neuroscience Department of Brighton and Sussex Medical School conducted breathwork research in a physiology lab and MRI scanner (from “Air Hunger” documentary). Credit: Air Hunger, directed by Bob van de Gronde, CC-BY 4.0 (creativecommons.org) Breathwork while…

Credit: Christina Morillo from Pexels For African American patients undergoing mastectomy, the risk of complications and the postoperative appearance of the breast are among the important drivers of preferences for breast reconstruction, reports a study in Plastic and Reconstructive Surgery.…

Breast milk IgG orchestrates adaptive immune responses to gut antigens. Credit: Science (2025). DOI: 10.1126 Fred Hutchinson Cancer Center reports that maternal immunoglobulin G (IgG), ingested in the first week of life, restrained microbiota-dependent adaptive immune responses weeks later, after…

Overlap among the flexible clubs across AD groups at 20% threshold. (A) Venn diagram of the Flexible Clubs. (B) Regional distribution of members of the Flexible Clubs at 20% threshold. Credit: Journal of Alzheimer’s Disease (2025). DOI: 10.1177/13872877251360025 Some regions…

Three-dimensional reconstruction of a single microglia, showing astrocyte-derived inclusions (green) within the phagosome (purple) and peripheral processes following cocaine self-administration and withdrawal. Credit: Anze Testen, Reissner Lab A new study at the University of North Carolina at Chapel Hill has…

Multi-analyte test can accurately identify brain cancers using small samples of cerebrospinal fluid. Credit: Elizabeth Cook A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery…

ROC curves for differentiating MCI/mAD patients from CN controls (left panel) or MCI patients from mAD patients (right panel) using the novel physio-marker CDI (blue), A? PET-SUVR (red), MoCA (green), and MMSE (black). Credit: Alzheimer’s & Dementia: Diagnosis, Assessment &…

Effects of BPS and alternative color developers on lipid droplets in KGN cells. Credit: Toxicological Sciences (2025). DOI: 10.1093/toxsci/kfaf096 Chemicals used to replace bisphenol A (BPA) in food packaging can trigger potentially harmful effects in human ovarian cells, according to…

Credit: cottonbro studio from Pexels A first-of-its-kind Blood Pressure Treatment Efficacy Calculator built on data from nearly 500 randomized clinical trials in over 100,000 people allows doctors to see how much different medications are likely to lower blood pressure. The…

Credit: Karolina Grabowska from Pexels A new blood test pioneered by diagnostics company AOA Dx (AOA) can detect ovarian cancer in symptomatic women with high accuracy, a study by researchers from the Universities of Manchester and Colorado has found. The…

Model performance for classifier to predict infection status. Credit: Diabetologia (2025). DOI: 10.1007/s00125-025-06502-7 Researchers at Karolinska Institutet, KTH Royal Institute of Technology and SciLifeLab have developed a new method for detecting early signs that the disease type 1 diabetes is…

Pathway analysis of ALS based on differentially abundant plasma proteins. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03890-6 By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease. This…

Biomarkers in Sturge-Weber syndrome. MRI and EEG biomarkers have provided the most robust and clinically relevant biomarkers. Urine angiogenic biomarkers offer promising data for use as affordable and non-invasive biomarkers; however, additional research and replication of past research is required…

A new study by researchers at Baylor College of Medicine brings hope for a more personalized approach to treating estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer. The team identified a biomarker in preclinical ER+ breast…

Credit: Biomaterials (2025). DOI: 10.1016 Researchers at National Taiwan University developed a biodegradable, electroconductive self-healing hydrogel combined with acupuncture that restores motor function and protects brain neurons in Parkinson’s disease models. Parkinson’s disease is a progressive brain disorder that causes…

Credit: Cyborg and Bionic Systems (2025). DOI: 10.34133 Conventional wearable sweat sensors utilize hydrophobic ion-selective membranes (ISMs) and require tight contact and adhesives to achieve signal stability. However, this can lead to user discomfort and skin-related diseases, necessitating the development…

For patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs), long-term routine laboratory toxicity monitoring (lt-RLTM) indicates that most very abnormal laboratory results are already known or suspected, according to a study published online Aug. 26 in the Annals…

As much as 80% of young people from the lowest social levels drop out of sports during adolescence. “Two-thirds from the highest socio-economic class drop out, three-quarters from the middle class, while from the lowest class, 4 out of 5…

The backpack is as much a part of school life as homework, pencils and recess. Kids use backpacks to carry everything they need during the day and make a fashion statement. Unfortunately, the excess weight of supplies stuffed into an…

The backpack, known as the Gyropack, uses gyroscopic technology similar to that used in space stations or large satellites to maintain orientation in space. Credit: Delft University of Technology A newly designed backpack, incorporating aerospace technology, shows promise as a…

For some people, sleep brings a peculiar kind of wakefulness. Not a dream, but a quiet awareness with no content. This lesser-known state of consciousness may hold clues to one of science’s biggest mysteries: what it means to be conscious.…

Credit: Ivan Samkov from Pexels Autistic children with mild to moderate developmental delay will no longer be eligible for the National Disability Insurance Scheme (NDIS) from mid-2027. Instead, they will be directed to a new support system called Thriving Kids.…

QUT researchers have created a powerful new tool that could predict when an athlete is at risk of suffering another injury when returning to play from a previous injury. It uses data from wearable sensors capturing how the athlete moves…

For patients with nonambulatory type 2 or type 3 spinal muscular atrophy, apitegromab, a monoclonal antibody that inhibits myostatin activation, improves motor function versus placebo, according to a study published online Aug. 13 in the Lancet Neurology. Thomas O. Crawford,…

In 2023, more than 2.4 million cases of syphilis, gonorrhea, and chlamydia were diagnosed in the U.S. Though that number is high, it’s actually an improvement, according to the Centers for Disease Control and Prevention: The number of sexually transmitted…

Pediatricians should screen children annually for mental or developmental issues, the American Academy of Pediatrics (AAP) recommends in a new clinical report. The recommendation comes in response to a mental, emotional and behavioral health crisis that’s been brewing among America’s…

Overview—therapies in alleviating cancer-induced GI symptoms. Credit: Advances in Nutrition (2025). DOI: 10.1016 Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients’ quality of life or…

When asked to choose between bad outcomes from lockdowns, most Americans said they’d rather risk more COVID deaths than allow more child abuse, domestic violence or deaths caused by economic hardship. A new University of Michigan study, published in the…

Microbiota changes during withdrawal therapy. Credit: Alcohol, Clinical and Experimental Research (2025). DOI: 10.1111 Alcohol withdrawal is associated with positive changes in the composition and function of the gut microbiome, improving our understanding of the gut’s influence on physiological and…

Changes in unhealthy alcohol use over time can be measured by a simple questionnaire at annual primary care visits. A study published in Alcohol, Clinical and Experimental Research found that in a primary care population that is regularly screened for…

This micrograph shows a small intestine organoid, a miniature model of mouse intestinal tissue. Experiments in these organoids helped UC San Diego researchers reveal a new underlying mechanism driving alcoholic liver disease. Credit: UC San Diego Health Sciences Alcohol-associated liver…

In recent years, binge drinking and alcohol use disorder (AUD) rates during pregnancy have increased significantly in the United States, eclipsing even opioids. Evidence-based treatments for AUD include medications and counseling. Still, these are underused, including during pregnancy when both…

Graphical Abstract. Credit: European Heart Journal – Digital Health (2025). DOI: 10.1093/ehjdh/ztaf064 An AI tool could help cardiologists identify and target cells that trigger arrhythmia in patients with ventricular tachycardia, a serious heart condition. A new study published in European…

VaxSeer features a two-track model for predicting the coverage score. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03917-y Every year, global health experts are faced with a high-stakes decision: Which influenza strains should go into the next seasonal vaccine? The choice must…

Credit: Genomics, Proteomics & Bioinformatics (2025). DOI: 10.1093/gpbjnl/qzaf040 Deep inside the body, a slow-growing cluster of mutated blood cells can form. This cluster, found in 1 in 5 older adults, can raise the risk of leukemia and heart disease, often…

Study design overview. Credit: Nature Methods (2025). DOI: 10.1038/s41592-025-02797-x Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and published in Nature…

Image processing and extraction of individual sperm heads from Diff-Quik stained images. Credit: Human Reproduction Open (2025). DOI: 10.1093/hropen/hoaf024 A research team from the Department of Obstetrics and Gynecology at the University of Hong Kong’s LKS Faculty of Medicine (HKUMed)…

When genetic testing reveals a rare DNA mutation, doctors and patients are frequently left in the dark about what it actually means. Now, researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful new way to…