Day February 6, 2026

HMN 2026: How genetic interactions are linked to heart disease

Single-cell image analysis of epistatic gene-silencing effects on cardiomyocyte hypertrophy. Credit: Nature Cardiovascular Research (2025). DOI: 10.1038/s44161-025-00656-8 Euan Ashley’s lab explores the intricate interactions of gene variants. Tiny “typos,” or genetic mutations, can sneak into segments of DNA. Many of…

HMN 2026: What are the drug combinations that protect stem cell heart grafts from rejection

Optimized immunosuppressive regimens support the survival of transplanted iPSC-CMs without immune rejection, advancing safer regenerative therapies for severe heart failure. Credit: Thomas van de Vosse from Openverse https://openverse.org/image/dd495ba1-0b32-44c7-9255-3f68cb040ced?q=pills+and+tablets&p=60 While current clinical trials for cardiac regeneration using induced pluripotent stem cell-derived…