Day April 8, 2026

MF-8 is able to induce CCKBR internalization at a low concentration. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-65962-y Scientists at City University of Hong Kong (CityUHK) have made progress in recent months with the discovery of a novel compound, named MF-8.…

In the first head-to-head comparison of two devices intended to protect against stroke in patients undergoing transcatheter aortic valve replacement (TAVR), the investigational Emboliner device performed comparably to the Sentinel device, which is approved by the U.S. Food and Drug…

A study published in Contemporary Economic Policy investigated the extent to which a company’s political investments influence their success in the competition for federal contracts. The study, which analyzed information on S&P 1500 firms from 1999 to 2019 available from…

Pie chart showing the number of individuals with unsolved NDD in 100kGP explained by pathogenic variants in the recently described ‘RNU-opathy’ genes. Credit: Nature Genetics (2026). DOI: 10.1038/s41588-026-02551-9 A 6-year-old girl is one of more than 80 people worldwide who…

Breathing in common disinfectant chemicals known as quaternary ammonium compounds, or QACs, may be far more harmful than swallowing them, according to a mouse study led by researchers at the University of California, Davis. The study found significant lung injury…

For the first time, people who want to stop using crystal methamphetamine may be able to treat their addiction with a cheap and readily available medication, say researchers at the National Drug and Alcohol Research Center (NDARC), UNSW Sydney. Results…

The brain? It has a flexible social perception. In interactions with people from different ethnic groups, it tends to respond more inclusively when a shared national identity is made salient. A study, by the University of Trento, Italy, and Nanyang…

Credit: Daly Selva Lira from Pexels The two of us can often be found in a patch of scrubby bushland, phone in hand, slowly scanning for plants. Or crouched behind a tree trunk with binoculars, pausing mid-breath to find the…

A prototype wafer shows various configurations that the Stahl lab tested before settling on their current design. Credit: UC Berkeley photo by Mathew Burciaga Over one billion people worldwide are over 60, and the population is projected to more than…

Lots of children and teenagers are open to a vegetarian or vegan diet and cut out meat but then struggle to keep it up, according to a new study from the University of Exeter. The study, published in Psychology of…

A new study published in Otolaryngology?Head and Neck Surgery, finds that children with tympanostomy tubes who swim in treated pools are not at increased risk of ear drainage, while those exposed to untreated or natural bodies of water face significantly…

Credit: Chemical Research in Toxicology (2026). DOI:10.1021 Researchers have long associated per- and polyfluoroalkyl substances (PFAS), commonly known as “forever chemicals,” with certain severe birth defects, but exactly how these pollutants harm a developing fetus has remained mostly a mystery.…

Researchers at WashU Medicine have shown that a novel compound they developed can clear a harmful protein from human neurons modeling frontotemporal dementia (shown) and prevent those neurons from dying. Credit: Farzané Mirfakhar New research from Washington University School of…

Signalling pathway regulating food intake in the model organism Caenorhabditis elegans. Credit: Hannah Lentschat/Leipzig University An international team, including scientists from Leipzig University, has gained important new insights into the regulation of food intake in mammals. The study, recently published…

Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals…

Experimental design and computational workflow. Credit: Genome Biology (2026). DOI: 10.1186/s13059-026-04002-4 Researchers at the Josep Carreras Leukaemia Research Institute have demonstrated that combining data from different origins enables a more precise characterization of cell type’s diversity into tissues and organs.…

Representative histological images of jejunal tissue after six weeks of recovery by diet. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-70644-4 Many people with celiac disease are advised to eat more fiber to support digestion and manage symptoms, either through diet or…

An acute pulmonary embolism occurs when a blood clot blocks one or more vessels in the lung. In patients at moderate or high risk, the blockage can impair the heart’s ability to pump blood through the lungs to such an…

Subcortical differences from adjusted analysis between people who use cannabis or tobacco and people who do not. Credit: Addiction (2026). DOI: 10.1111 Cannabis and tobacco—whether used on their own or together—can affect the brain’s structure. A recent study involving systematic…

When patients start getting treated for conditions like psoriatic arthritis, or connective tissue diseases like lupus and systemic sclerosis, their heightened risk of cancer gradually decreases, according to a new five-year study tracking people with immune-mediated inflammatory diseases (IMID). Scientists…

Credit: Tima Miroshnichenko from Pexels Family physicians who report feeling burned out are nearly 1.5 times more likely to change practices or stop practicing medicine entirely than their peers who don’t report burnout, a study by Weill Cornell Medicine researchers…

An image of the model axons covered in oligodendrocytes, specialized cells of the brain that produce myelin. The model axons and oligodendrocytes are too small to be photographed by normal cameras, so the image was taken with a scanning electron…

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated networks. But scientists have had limited tools for selectively turning these specific connections “on”…

Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression and mechanisms that regulate gene function—or epigenetics. Egervari said, “We recently uncovered that metabolites from…

Multimodal imaging protocol for simultaneous measurement of brain water content, electrophysiological, and hemodynamic processes. Credit: Proceedings of the National Academy of Sciences (2026). DOI: 10.1073 Sleep helps the brain to cleanse itself—and now this process can be measured in humans…

A major drawback of ketamine when used as an antidepressant is that depressive symptoms often reappear within a few weeks. In this study, researchers found that NOX-1 inhibition could extend the antidepressant effects of ketamine. Moreover, a newly developed compound,…

Complement pathway proteins are involved in immunoglobulin A-containing immune complex (IgA-IC) formation and deposition in the kidneys. Elevated complement factor H-related protein 1 (CFHR1) may be a biomarker for susceptibility to IgA nephropathy. Immunosuppressive treatment reduces IgA-IC formation and increases…

A feedback loop linking healthy aging to NAD metabolism, gut microbiome activity, renal function, and oxidative stress. Markers of increased NAD synthesis and/or reduced inflammation (tryptophan/kynurenine), a healthy gut bacterial metabolism (aspartate/quinolinate, ergothioneine/TMAO), and reduced oxidative stress (methionine/methionine sulfoxide) are…

Among stable, relatively low-risk patients who had previously suffered a heart attack, discontinuing beta-blockers after at least one year was found to be non-inferior, or comparable, to continuing beta-blockers in terms of death, another heart attack or hospitalization for heart…

Among middle-aged and older men, a higher percentage of total food weight from ultraprocessed food (UPF) is associated with a higher risk for incident benign prostatic hyperplasia (BPH), according to a study published online March 14 in the Nutrition Journal.…

Imagine being asked to sit alone in a quiet room for 15 minutes with nothing to do—no phone, no music, no external distraction. In a well-known 2014 study, many participants found that task so challenging that they chose to press…

The first randomized trial to test whether adding a small, temporary pump to allow the heart to rest and intentionally delaying percutaneous coronary intervention (PCI), also known as coronary angioplasty, for 30 minutes to reduce heart damage compared with standard…

A new study from the University of Chicago shows how an ingredient from lithium batteries could form the foundation of treatments for pain relief or other disorders. Above, a tiny, flexible patch that can be interfaced with neural tissue to…

A Stanford study shows that jail-based hepatitis C programs could cut new infections by nearly half among people who inject drugs, potentially providing a major boost to lagging U.S. efforts to meet national hepatitis C elimination goals. The study, published…

Most vaccines are designed to stimulate antibodies that block infection. Researchers at UW–Madison are working on a way to harness T cells in a way that could extend immunity, meaning fewer vaccine boosters for patients. Credit: Jeff Miller / UW–Madison…

Model of the NleD-PPM1A complex. Credit: Advanced Science (2026). DOI: 10.1002 Researchers have uncovered how a disease-causing bacterium uses a single protein to interfere with the body’s defenses in more than one way, offering a clearer picture of how infections…

A summary of pPDT and pPDXT generation, amplification and biobanking and their use in drug screening and other applications. Credit: Nature Protocols (2026). DOI: 10.1038/s41596-026-01347-9 Biopsy-derived organoids, accurate models of disease, are used to search for new drugs. Now, results…

Map of GALA collection sites across the Americas. Credit: Marina Natividad Avila, MSc A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with…

Asthma in older age is associated with other comorbidities, according to a study published in the Journal of Asthma and Allergy. Martyna Miodo?ska, from the Medical University of Silesia in Katowice, Poland, and colleagues conducted a multicenter cross-sectional study of…

Researchers from Stellenbosch University collect water samples at a wastewater treatment facility in an urban center in South Africa to investigate how antimicrobial resistance genes move through water systems. Credit: JP Makumbi In South Africa, wastewater treatment plants (WWTPs) and…