Day April 27, 2026

Our brains anticipate sensory signals—such as sight, sound, smell, or touch—by relying on past experiences. When we bite into an apple, for example, we expect a sweet crunch because of all the other times we have eaten one. Some neuroscientists…

Clinical responses and survival outcomes. Credit: Nature Medicine (2026). DOI: 10.1038/s41591-025-04175-8 Multiple myeloma is the second most common blood cancer in adults. It starts in the white blood cells that are responsible for creating antibodies that help the body fight…

WashU Medicine researchers have described how mRNA cancer vaccines engage the immune system, through an unconventional pathway involving two subsets of immune cells called dendritic cells. Credit: Sara Moser/WashU Medicine The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed…

Credit: Roberto Hund from Pexels Depression is among the most widespread mental health disorders worldwide, affecting an estimated 1 in 20 people. It is characterized by persistent sadness, hopelessness, disrupted sleep patterns, changes in appetite and a loss of interest…

Social media videos are claiming that mouthwash can raise the risk of blood pressure—and potentially damage heart health. According to some of these videos, this is caused by mouthwash wiping out “good” oral bacteria that are important for the cardiovascular…

Credit: UMG/Swen Pförtner An international research team with the participation of researchers from the University Medical Center Göttingen (UMG), Germany, has developed a mouse model that offers new insights into the development of a rare but serious muscle disease. The…

Illustration of the dedifferentiation-associated mechanistic pathway before and after BRAF inhibition. Credit: bioRxiv DOI: 10.1101/724740 Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction…

Estrobolome-facilitated reabsorption of estrogens. Credit: Proceedings of the National Academy of Sciences (2026). DOI: 10.1073 Our industrialized, modern lifestyles may be increasing how much estrogen (the female sex hormone) gets recycled in our bodies, according to a study published in…

Active mitochondria are needed for optimal anti-tumor immunotherapy with cDC1s. While control cDC1 vaccine is effective in reducing the metastasis of intravenously injected B16-OVA tumors, the cDC1s with impaired mitochondria show less effective cancer immunotherapy. Credit: CNIC Researchers at the…

Extracellular donor mitochondria are delivered specifically to neurons via bispecific protein binders. Credit: IOB, 2026 Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have developed MitoCatch, a system that enables targeted delivery of…

Reversing hallmarks of rapid aging by silencing a cellular alarm system: single-molecule fluorescent in-situ hybridization (smFISH) in killifish female ovaries, visualizing immature oocytes (ddx4) in red, and for granulosa cells (lhr) in green. Nuclei are visible in blue. Credit: Eitan…

Fluorescent image of a brain organoid showing a neuroepithelial structure. Neurons are labeled in green (TUJ1 staining), while cell nuclei are shown in blue (DAPI). Scale bar: 50 ?m. Credit: Machairaki lab Scientists from Johns Hopkins Medicine report new evidence…

A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in…

Image: Prof Jacob (R) and his team of MAP researchers (L to R) Muliyana Arifudin, Gopika Kaimal and Dr Saeed Moarrefi, in front of their pyrolysis equipment.  Credit: James Cook University Research published in the Journal of Analytical and Applied…

Hydrodynamic model of swimming E. coli passing through a channel. Credit: Nature Physics (2026). DOI: 10.1038/s41567-026-03189-4 At the Institute of Science and Technology Austria (ISTA), Jérémie Palacci’s research group is venturing into metallurgy—albeit with a twist. Instead of traditional tools,…

Researchers at Cincinnati Children’s, working with collaborators at University College London and Oak Ridge National Laboratory, have identified a practical, data-centered strategy to reduce bias in artificial intelligence (AI) systems used in children’s mental health care. The findings, published in…

Past exposure to metabolic stress can be “tattooed” on CD8+ T cells, inducing a lasting vulnerability to an iron-dependent form of cell death known as ferroptosis, particularly in the tumor context. Metabolic tattooing of CD8+ T cells can potentially be…

A student views her cell phone at Ronald McNair Sr. High School, Aug. 7, 2025, in Atlanta. Credit: AP Photo/Mike Stewart, File Experts wish more people spotted the signs earlier: feeling overwhelmed, not feeling “like yourself,” shifts in sleep, behavior…

Temporal clustering of circulating proteins across the menstrual cycle. Credit: Nature Medicine (2026). DOI: 10.1038/s41591-026-04326-5 It is a process as old as humanity itself, yet there is still much we do not know about women’s menstrual cycle and the impact…

Nearly 12,000 people in the U.K. who received a first dose of the MenB vaccine will now be offered a second shot starting next week, after a deadly meningitis outbreak linked to a university in Kent. The outbreak led to…

A research team led by Lea Lorenz of the RPTU University Kaiserslautern-Landau and Sven Kachel of the University of Kassel conducted a comprehensive meta-analysis that examined how men react to situations in which their masculinity is called into question. To…

As a researcher investigating how electric brain stimulation can improve people’s powers of recollection, I’m often asked how memory works—and what we can do to use it more effectively. Happily, decades of research have given us some clear answers to…

Credit: Current Biology (2026). DOI: 10.1016 Melatonin is a naturally produced molecule that has long been suspected to play a role in healthy sleep, but it has been unclear how it does so. Now, Caltech researchers have discovered a mechanism…

by Harvey L. Neiman Health Policy Institute New research from the Harvey L. Neiman Health Policy Institute found that most Merit-Based Incentive Payment System (MIPS) quality measures designated as “topped out” by the Centers for Medicare & Medicaid Services (CMS)…

A new survey from two food industry groups shows growing interest in meat as a “healthy” food choice, even as doctors warn that too much red meat can raise health risks. More than 75% of U.S. consumers now see meat…

Shot two hawks with one arrow: Above- and below-threshold breathing solitons, previously requiring separate theoretical descriptions, can now be reproduced accurately with a single unified framework—capturing all the key experimental behaviors in a single simulation. Credit: Aston University A team…

Respiratory syncytial virus (RSV) is a common virus that can cause severe respiratory illness in infants and young children, including lower respiratory tract infections (LRTIs) such as bronchiolitis and pneumonia. It is a leading cause of infant hospitalization worldwide, with…

Marriage, it turns out, may come with a side-effect no one puts in the vows: people who have been married seem less likely to develop cancer than those who have never married at all. That is the provocative finding from…

Attendees of the 2024 WomenLift Global Health Conference held in Tanzania gather for a mentorship breakfast. Credit: WomenLift Health Stanford researchers interviewed 21 global health leaders to identify specific strategies men can use to support women’s career advancement. Amanda Marr…

In many parts of East Africa, small pools of water that form after heavy rainfall are ideal breeding sites for the Anopheles mosquitoes that transmit malaria. Researchers at the Karlsruhe Institute of Technology (KIT) have analyzed how such environmental conditions…

Prenatal exposure to acetaminophen did not increase autism risk in children. Credit: Suzy Hazelwood for Pexels. Acetaminophen, which also goes by names like paracetamol or Tylenol, is a common over-the-counter pain reliever and fever reducer. It is often prescribed during…

Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated. In a new study published in Nature Communications, investigators found that EZH2—a…

Madagascar is home to seven species of baobab trees, of which six are found nowhere else on the planet. Many of the trees have been alive for well over 1,000 years. The ancient trees have become symbols of Madagascar itself.…

DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH A machine learning model analyzing CpG-based DNA methylation accurately predicted the origin of many different cancer types in patients with cancers of unknown primary (CUP),…

Chelsea Magin joined CU Denver|CU Anschutz in 2016 and holds appointments in Biomedical Engineering (primary), Pediatrics, and Medicine. She holds multiple degrees including a bachelor’s degree in material science and engineering and a doctorate in biomedical engineering from the University…

A recent study shows that sterically demanding diphenylanthracene-based artificial ?-luminophores can be programmed to self-fold and preorganize into highly ordered supramolecular nanotubes. This folding-mediated assembly guides directional ?–? stacking and cooperative interactions, enabling the formation of stable curved architectures. Notably,…

A widely used anxiety medication is being pulled from shelves due to “failed dissolution specifications,” the U.S. Food and Drug Administration (FDA) said. The agency’s enforcement report said that one lot of Xanax has been recalled nationwide by the company…

Scientists have discovered extensive, ancient and modern deep-sea coral reefs within the Galapagos Marine Reserve (GMR)—the first of their kind ever to be documented inside the marine protected area (MPA) since it was established in 1998. The first reef observed…

Credit: Gustavo Fring from Pexels Cognitive decline not only affects a woman’s quality of life but also her ability to lead an independent lifestyle later in life. A new large-scale study suggests that a longer reproductive lifespan, resulting in greater…

Taking part in activities can make you less lonely, because you meet people, and because social gatherings are a positive thing. But can the mere fact of being active, especially in natural surroundings, help prevent loneliness? “The conclusion is that…