Antifibrinolytic agents may be used in
specific situations or in combination with clotting factor replacement to treat
hemophilia. Antifibrinolytic agents prevent the
breakdown of blood clots by neutralizing chemicals in the
mucous membranes of the mouth, nose, and urinary tract
that break down clots.
Why It Is Used
Antifibrinolytic agents are used to
treat nosebleeds (epistaxis) and to help prevent bleeding in the mouth before
How Well It Works
Antifibrinolytic agents effectively
prevent bleeding of the mouth when they are combined with a preventive dose of
Possible side effects of
antifibrinolytic agents include:
blood pressure (hypotension).
See Drug Reference for a full list of side effects. (Drug
Reference is not available in all systems.)
What To Think About
Clotting factors are more
effective than antifibrinolytic agents. However, antifibrinolytic medicines may
be given instead of or along with clotting factors in certain situations. For
example, antifibrinolytic agents may be used to:
Help prevent bleeding in the mouth, nose, or
urinary tract only.
Help prevent bleeding after dental surgery
instead of clotting factor replacement.
Also, unlike clotting factors, antifibrinolytic medication
can be taken in pill or liquid form and do not have to be injected.