Von Willebrand Disease

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Von Willebrand Disease

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Von Willebrand Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • vWD

Disorder Subdivisions

  • Angiohemophilia
  • Constitutional Thrombopathy
  • Minot-Von Willebrand Disease
  • Pseudohemophilia
  • Vascular Hemophilia
  • Willebrand-Juergens Disease
  • Von Willebrand disease type I
  • Von Willebrand disease type II
  • Von Willebrand disease type III

General Discussion

Von Willebrand disease (vWD) is an inherited bleeding disorder resulting in prolonged bleeding. Certain specialized proteins called clotting factors aid the blood to clot. Individuals with von Willebrand disease have a defect in or deficiency of one of these proteins known as von Willebrand factor. They may also have low levels of an additional factor known as factor VIII.

Deficient or defective von Willebrand factor results in improper functioning of platelets, specialized red blood cells that mass together to form clots to stop bleeding. In individuals with von Willebrand disease, platelets do not stick to holes in blood vessels and bleeding is prolonged.

Von Willebrand disease is inherited as an autosomal dominant or recessive trait.

Resources

National Hemophilia Foundation
116 West 32nd Street, 11th Floor
New York, NY 10001
USA
Tel: (212)328-3700
Fax: (212)328-3777
Tel: (800)424-2634
Email: handi@hemophilia.org
Internet: http://www.hemophilia.org

Canadian Hemophilia Society
400-1255 University Street
Montreal
Quebec, H3B 3B6
Canada
Tel: 514-848-0503
Fax: 514-848-9661
Tel: 800-668-2686
Email: chs@hemophilia.ca
Internet: http://www.hemophilia.ca

NIH/National Heart, Lung and Blood Institute
P.O. Box 30105
Bethesda, MD 20892-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov
Internet: http://www.nhlbi.nih.gov/

World Federation of Hemophilia
1425 René Lévesque Blvd. W. Suite 1010
Montreal
Quebec, Intl H3G 1T7
Canada
Tel: +1 (514) 875-7944
Fax: +1 (514) 875-8916
Email: wfh@wfh.org
Internet: http://www.wfh.org/index.asp?lang=EN

Hemophilia Federation of America
210 7th St. SE
Suite 200B
Washington, DC 20003
USA
Tel: (202)675-6984
Fax: (202)675-6983
Tel: (800)230-9797
Email: info@hemophiliafed.org
Internet: http://www.hemophiliafed.org

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx
Internet: http://rarediseases.info.nih.gov/GARD

Madisons Foundation
PO Box 241956
Los Angeles, CA 90024
Tel: (310)264-0826
Fax: (310)264-4766
Email: getinfo@madisonsfoundation.org
Internet: http://www.madisonsfoundation.org

Irish Haemophilia Society
First Floor
Cathedral Court
New Street
Dublin, 7
Ireland
Tel: +353 (0)1 657 99 00
Fax: +353 (0)1 657 99 01
Email: info@haemophilia.ie
Internet: http://www.haemophilia.ie/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  7/23/2007
Copyright  1987, 1988, 1990, 1991, 1992, 1994, 1996, 1998, 1999, 2006, 2007 National Organization for Rare Disorders, Inc.

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