Intestinal Pseudoobstruction

Search Knowledgebase

Topic Contents

Intestinal Pseudoobstruction

National Organization for Rare Disorders, Inc.

It is possible that the main title of the report Intestinal Pseudoobstruction is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


  • Chronic Idiopathic Intestinal Pseudoobstruction
  • CIIP
  • Hypomotility Disorder
  • Pseudointestinal Obstruction Syndrome
  • Pseudoobstructive Syndrome

Disorder Subdivisions

  • None

General Discussion

Intestinal pseudoobstruction is a digestive disorder that may be present at birth. The intestinal walls are unable to contract normally (hypomotility) to generate wave-like (peristaltic) motion. This condition resembles a true obstruction, but no such blockage exists. Abdominal pain, vomiting, diarrhea, constipation, malabsorption of nutrients leading to weight loss and/or failure to thrive, are signal signs. Enlargement of various parts of the small intestine or bowel also occur.

There are two kinds of Intestinal pseudoobstruction, depending on the source of the failure of the gastrointestinal tract. If the problem is abnormal functioning of the nerves of the abdominal wall leading to non-synchronized contractions, then the episode is classified as neurogenic and the disorder is known as neuropathic pseudoobstruction. If the functional failure can be traced to weak or absent contractions of the muscle itself, then it is classified as myogenic and the disorder is known as myopathic pseudoobstruction.


Association of Gastrointestinal Motility Disorders, Inc.
12 Roberts Drive
Bedford, MA 01730
Tel: (781)275-1300
Fax: (781)275-1304

NIH/National Institute of Diabetes, Digestive & Kidney Diseases
Office of Communications & Public Liaison
Bldg 31, Rm 9A06
31 Center Drive, MSC 2560
Bethesda, MD 20892-2560
Tel: (301)496-3583

International Foundation for Functional Gastrointestinal Disorders
P.O. Box 17864
Milwaukee, WI 53217
Tel: (414)964-1799
Fax: (414)964-7176
Tel: (888)964-2001

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333

Bowel Group for Kids Inc.
PO Box 40
Oakdale, NSW, 2570
Tel: 02 4659 6067
Fax: 61 2 4659 6381

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223

3 St. Andrews Place
London, NW1 4LB
Tel: 020 7486 0341
Fax: 020 7224 2012

Gastroparesis & Dysmotilities Association
5520 Dalhart Hill N.W.
Calgary, AB, T3A 1S9
Tel: 403-247-3215

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site or email

Last Updated:  4/17/2008
Copyright  1987, 1988, 1989, 1994, 2003 National Organization for Rare Disorders, Inc.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information.