Lupus and Antiphospholipid Antibody Syndrome

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Lupus and Antiphospholipid Antibody Syndrome

Topic Overview

About 1 in 3 people with lupus produce an antibody that attacks certain blood-clotting factors, which can cause the blood to clot easily.1 A person who has this antibody and has had blood clots is said to have antiphospholipid antibody syndrome. This can lead to mild or severe blood-clotting complications, including:

Antiphospholipid antibodies can be detected with a blood test. When diagnosed, the condition is usually treated with anticoagulants. Pregnant women with antiphospholipid antibody syndrome require close monitoring.

References

Citations

  1. Crow MK (2008). Systemic lupus erythematosus. In L Goldman, D Ausiello, eds., Cecil Textbook of Medicine, 23rd ed., pp. 2022–2032. Philadelphia: Saunders Elsevier.

Credits

By Healthwise Staff
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Primary Medical Reviewer Andrew Swan, MD, CCFP, FCFP - Family Medicine
Specialist Medical Reviewer Stanford M. Shoor, MD - Rheumatology
Last Revised July 8, 2010

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