Antihistamines for Morning Sickness

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Antihistamines for Morning Sickness

Topic Overview

Certain antihistamines such as doxylamine or dimenhydrinate, taken as your doctor advises, may relieve morning sickness.1 Doxylamine is a non-prescription medicine that is sold as Unisom-2 Tablets. If one of these antihistamines alone does not relieve your morning sickness, you can try taking it with vitamin B6.2

A pill that contains vitamin B6 and doxylamine (Diclectin) is available by prescription.

Talk to your doctor about the right doxylamine dosage for you.

Note: Do not confuse Unisom-2 Tablets with Unisom SleepGels or Unisom, which contain a different medicine.

References

Citations

  1. Festin M (2007). Nausea and vomiting in early pregnancy, search date May 2008. Online version of BMJ Clinical Evidence: http://www.clinicalevidence.com.
  2. Kelly TF, Savides TJ. (2009). Gastrointestinal disease in pregnancy. In RK Creasy et al., eds., Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice, 6th ed., pp. 1041–1057. Philadelphia: Saunders Elsevier.

Credits

By Healthwise Staff
Primary Medical Reviewer Sarah Marshall, MD - Family Medicine
Primary Medical Reviewer Brian D. O'Brien, MD - Internal Medicine
Specialist Medical Reviewer Kirtly Jones, MD, MD - Obstetrics and Gynecology
Last Revised January 27, 2011

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