Dapsone

pronounced as(dap' sone)

Why is this medication prescribed?

Dapsone is used to treat leprosy and skin infections.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Dapsone comes as a tablet to take by mouth. Dapsone usually is taken either once a day or three times a week. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dapsone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

What special precautions should I follow?

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Before taking dapsone,

  • tell your doctor and pharmacist if you are allergic to dapsone, sulfa drugs, phenylhydrazine, naphthalene, niridazole, nitrofurantoin, primaquine, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aminobenzoate potassium (Potaba), aminobenzoic acid, clofazimine (Lamprene), didanosine (Videx), probenecid (Benemid), pyrimethamine (Daraprim), rifampin (Rifadin), trimethoprim (Bactrim, Cotrim, Septra), or vitamins.
  • tell your doctor if you have or have ever had anemia or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dapsone, call your doctor.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Dapsone may make your skin sensitive to sunlight.

What special dietary instructions should I follow?

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Dapsone may cause an upset stomach. Take dapsone with food or milk.

What should I do if I forget a dose?

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Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

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Dapsone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • upset stomach

  • vomiting

If you experience any of the following symptoms, call your doctor immediately:

  • sore throat

  • fever

  • rash

  • yellowing of the skin or eyes

  • unusual bruising

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

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Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

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In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

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Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to dapsone.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Other names

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  • DDS
  • diaminodiphenylsulfone

Last Reviewed - 04/01/2012

AHFS® Consumer Medication Information. © Copyright, 2012. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.