Your doctor has prescribed letrozole for you. Letrozole comes as a tablet to take by mouth.
treat breast cancer that has spread within the breast or to other areas of the body.
treat early breast cancer in women who have already been treated with surgery, radiation and/or chemotherapy. Letrozole is sometimes used right after these treatments and sometimes after 5 years of treatment with a medication called tamoxifen (Nolvadex). Letrozole is used to stop any cancer cells that remain after these treatments from spreading.
Letrozole is in a class of medications known as nonsteroidal aromatase inhibitors. It decreases the amount of estrogen produced by the body. This can slow or stop the growth of some breast tumors that need estrogen to grow.
Letrozole is usually taken once a day, with or without food. Try to take letrozole at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain anything you do not understand. Take letrozole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You may need to take letrozole for several years or longer. Continue to take letrozole even if you feel well. Do not stop taking letrozole without talking to your doctor.
If you forget to take a dose of letrozole, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose and do not take more than one dose of letrozole in one day.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
hot flushes
night sweats
nausea
vomiting
muscle, joint, or bone pain
excessive tiredness
headache
dizziness
muscle weakness
swelling of the hands, feet, ankles, or lower legs
loss of appetite
constipation
diarrhea
stomach pain
difficulty falling asleep or staying asleep
vaginal bleeding or irritation
breast pain
flu-like symptoms
difficulty urinating
pain on urination
cough
rash
chest pain
difficulty breathing
Letrozole may cause or worsen osteoporosis. Talk to your doctor about the risk of taking this medication and to find out what you can do to decrease this risk.
Letrozole may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
Keep letrozole in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist if you have any questions about refilling your prescription.
Last Reviewed - 04/01/2012
AHFS® Consumer Medication Information. © Copyright, 2012. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.