1. (Page 8: End of “Validation and diagnostic accuracy of miR-203 and miR-205 expression
in FNA samplesâ€)
Please replace
All in all, the sensitivity rate for both markers was 92.9 % (39/42, CI 95 %, 80.5–98.4),
with a specificity level of 100 % (71/71, CI 95 %, 94.9–100) (Table 2; Figure 6B).
Table 2. Sensitivity and specificity values of microRNAs evaluated in discriminating metastatic
and non-metastatic lymph nodes in FFPE and FNA biopsies from lymph node samples
With the amended text
All in all, the sensitivity rate for both markers was 93.3 % (42/45, CI 95 %, 81.7–98.6),
with a specificity level of 100 % (68/68, CI 95 %, 94.7–100) (Table 2; Figure 6B).
Table 2. Sensitivity and specificity values of microRNAs evaluated in discriminating metastatic
and non-metastatic lymph nodes in FFPE and FNA biopsies from lymph node samples
2. (Page 8: End of “Validation and diagnostic accuracy of miR-203 and miR-205 expression
in FNA samplesâ€)
Please replace
Moreover, negative predictive values were of 95.9 % (95 % CI, 88.6–99.1 %) and positive
predictive values of 100 % (95 % CI, 90.9–100 %) for both microRNAs (Table 3).
Table 3. Accuracy characteristics of microRNAs in discriminating metastatic and non-metastatic
lymph nodes in FFPE and FNA biopsies from lymph node samples
With the amended text
Moreover, negative predictive values were of 95.9 % (95 % CI, 88.6–99.1 %) and positive
predictive values of 100% (95 % CI, 91.5–100 %) for both microRNAs (Table 3).
Table 3. Accuracy characteristics of microRNAs in discriminating metastatic and non-metastatic
lymph nodes in FFPE and FNA biopsies from lymph node samples