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Higher pain countenance tied to pro-nociceptive state

 

(HealthDay)—Sensory over-responsiveness (SOR) in differently healthy subjects is compared with a pro-nociceptive state, according to a investigate published online Aug. 7 in PAIN Practice.

Irit Weissman-Fogel, Ph.D., from a University of Haifa in Israel, and colleagues conducted psychophysical contrast in 30 healthy subjects (14 SOR and 16 non-SOR participants, formed on a Sensory Responsiveness Questionnaire). Testing evaluated (1) hyperalgesic responses; (2) instrumentation and sensitization to 14 phasic feverishness stimuli; (3) habituation; (4) 6 mins after-sensation; and (5) conditioned pain modulation (i.e., phasic feverishness stimuli practical with and but palm soak in prohibited water).

The researchers found that, compared to non-SOR individuals, a SOR organisation had a steeper escalation in numerical pain scale ratings to heat boost (P = 0.003) indicating hyperalgesia, increasing sensitization (P ? 0.001), habituation responses (P

“This is a initial investigate to news a coupling between a ubiquitous SOR to daily harmless stimuli and extended pain facilitation rather than deficient inhibition,” a authors write.


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