HMN 2025: What is the Support for continued use of nasogastric tube after esophageal cancer surgical procedure

Support for continued use of nasogastric tube after oesophageal cancer surgery
How the research was completed. Credit: Jakob Hedberg

In the most important Nordic study so far regarding esophageal cancer surgical procedure, the researchers discovered clear proof that decompression with a nasogastric tube is related to much less critical problems. Their outcomes problem a development of declining use of the nasogastric tube after main surgical procedures.

The study was led by Uppsala University and has been published in Lancet Regional Health Europe.

Numerous small research had beforehand steered that it’s secure to desert the custom of leaving in a decompressing—however for a lot of sufferers disagreeable—nasogastric tube after surgical procedure to take away .

The tube is plastic and runs from the nostril all the way down to the abdomen, and its use on this explicit context is to alleviate and cut back stress on this newly operated space.

When the query was mentioned in a Nordic analysis collaboration, it was concluded that these smaller research lacked enough statistical energy to justify a change in care.

Subsequently, a was carried out at 12 college hospitals throughout Sweden, Norway, Denmark and Finland, where sufferers have been randomized to have or not have a decompressing nasogastric tube of their esophagus following this kind of surgical procedure.

Patients with out the tube skilled leakage

To the researchers’ shock, it was not with out threat to omit the tube after this surgical procedure, as extra sufferers with out the tube skilled leakage within the anastomosis created through the operation. Leakage have to be handled instantly, typically with interventions underneath , leading to struggling for the affected person and an extended size of hospital keep.

Although no variations in or different problems have been discovered, this new data could aid to cut back struggling for sufferers sooner or later.

“Esophageal cancer is an unusual type of cancer, with solely about 200 operations of this sort being carried out per 12 months in Sweden,” says Jakob Hedberg, surgical oncologist, affiliate professor at Uppsala University and advisor surgeon at Uppsala University Hospital who can be principal investigator for the research.

“National and worldwide cooperation is due to this fact completely crucial with a purpose to conduct sufficiently massive trials to reply the analysis questions we’ve got. The incontrovertible fact that in simply over two years, virtually 450 sufferers have been recruited for the trial surpassed our expectations and represents a fantastic success for this community.”

“Strong curiosity has been proven at worldwide conferences where our preliminary outcomes have been introduced, and the precept of constructing surgical care on stable proof has allowed us to supply the perfect care to our sufferers. Another essential impact of this profitable collaboration is that we are able to construct extra medical trials inside the Nordic community which has now been consolidated. In truth, the subsequent medical trial is already underneath growth,” says Hedberg.

More data:
Jakob Hedberg et al, Nasogastric tube after oesophagectomy and threat of anastomotic leak: a Nordic, multicentre, open-label, randomised, managed, non-inferiority trial, The Lancet Regional Health – Europe (2025). DOI: 10.1016/j.lanepe.2025.101411

Provided by
Uppsala University


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