HMN 2025: How The danger of postoperative proliferative vitreoretinopathy is decrease with hashish use

Patients present process retinal detachment (RD) restore with concomitant hashish use have a decrease danger of subsequent proliferative vitreoretinopathy (PVR) and requiring subsequent advanced RD restore, in line with a review published on-line July 3 in JAMA Ophthalmology.

Ahmed M. Alshaikhsalama, M.D., from the UT Southwestern Medical Center in Dallas, and colleagues examined the chance of growing PVR amongst sufferers with concomitant hashish use who underwent RD restore in a retrospective cohort study.

Participants underwent preliminary RD restore with pars plana vitrectomy with or with out scleral buckle (SB), main SB, or pneumatic retinopexy. Patients identified with concomitant cannabis-related dysfunction along with confirmatory testing of hashish in urine or blood have been in comparison with a {control} group with out documented use. After propensity rating matching, every group had 1,193 sufferers.

The researchers discovered that in contrast with controls, sufferers with concomitant hashish use with RD repaired by any technique had a diminished danger for subsequent PVR (2.10 versus 4.36%; relative danger, 0.48) and requiring advanced RD restore (3.10 versus 5.03%; relative danger, 0.62) at six months. For each outcomes, outcomes have been comparable at one yr.

“While hashish use demonstrated a decrease relative danger for PVR, the small absolute discount (~2%) might not be clinically significant. Confounders might account for all of the noticed associations,” the authors write.

An Invited Commentary is published in the identical journal.

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