Researchers explore the role of of transposable elements in myocarditis

by KeAi Communications Co. This schematic illustrates the observation of extensive activation of immune genes and transposable elements (TEs) in mice with EAM. Credit: Sixing Chen Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation. Mammalian genomes contain a vast number of TEs. The diversity and abundance of these elements impact the structure, function and evolution of the genome. They influence gene regulatory networks by altering transcription factor binding sites and creating new enhancer activities. Read More