Scaffolding sensors detect early evidence of organ transplant rejections in mice

A petri dish holding microporous scaffold implants. Credit: Michele Santillan A new microporous scaffold functions as a minimally-invasive surveillance method to identify rejection prior to graft injury in a mouse model, according to a study published in Science Advances. These sensors are a first step towards developing a tool which could provide physicians with vital early information about the possibility of organ rejection in transplant patients. Solid organ transplantation is associated with aggressive immunosuppression to prevent graft rejection. However, over suppression can increase the risk of neoplasia and opportunistic infections, Read More