{"id":201298,"date":"2017-09-21T23:37:39","date_gmt":"2017-09-21T23:37:39","guid":{"rendered":"http:\/\/healthmedicinet.com\/i\/asthma-medication-cause-nightmares-and-depression\/"},"modified":"2017-09-21T23:37:39","modified_gmt":"2017-09-21T23:37:39","slug":"asthma-medication-cause-nightmares-and-depression","status":"publish","type":"post","link":"http:\/\/healthmedicinet.com\/i\/asthma-medication-cause-nightmares-and-depression\/","title":{"rendered":"Asthma medication cause nightmares and depression"},"content":{"rendered":"<ul class=\"mol-bullets-with-font\">\n<li class=\"\"><strong>Montelukast, sold in the US as Singulair, is a drug that helps manage asthma symptoms<\/strong><\/li>\n<li class=\"\"><strong>Researchers from the University of Groningen, Netherlands, analyzed the adverse reactions people experience from the drug\u00a0<\/strong><\/li>\n<li class=\"\"><strong>Patients have reported an increase in depression and nightmares\u00a0<\/strong><\/li>\n<li class=\"\"><strong>They say doctors should be more clear about the risks when prescribing it to patients \u00a0<\/strong><\/li>\n<\/ul>\n<p class=\"author-section byline-plain\">By<\/p>\n<p>Danielle Zoellner For Dailymail.com<\/a><\/p>\n<p class=\"byline-section\"><span class=\"article-timestamp article-timestamp-published\"><br \/>\n  <span class=\"article-timestamp-label\">Published:<\/span><br \/>\n  18:10 EDT, 21 September 2017<br \/>\n<\/span><br \/>\n | <span class=\"article-timestamp article-timestamp-updated\"><br \/>\n  <span class=\"article-timestamp-label\">Updated:<\/span><br \/>\n  18:12 EDT, 21 September 2017<br \/>\n<\/span>\n<\/p>\n<\/p>\n<ul>\n<li class=\"share-facebook\"><\/li>\n<li class=\"share-twitter\"><\/li>\n<li class=\"share-pinterest\"><\/li>\n<li class=\"share-gplus\">\n      <span class=\"g-interactivepost\"><br \/>\n        <a><\/a><br \/>\n      <\/span>\n        <\/li>\n<li class=\"share-email\">\n<p>                <span class=\"wai\">e-mail<\/span><br \/>\n            <\/a>\n        <\/li>\n<li class=\"share-icons\" id=\"shareLinkTop\">\n            <\/a>\n            <\/li>\n<\/ul>\n<p> <span><\/span><\/p>\n<p class=\"count-number\">           4<\/p>\n<p class=\"count-text\">View <br \/> comments<\/p>\n<p>    <\/a><\/p>\n<p class=\"mol-para-with-font\">A children&#8217;s asthma medication may cause nightmares and other mental health issues, a study claims.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Montelukast, sold in the US as Singulair, is a commonly prescribed asthma medication and one of the 18 best-selling drugs of the 21st century, according to Forbes.<\/p>\n<p class=\"mol-para-with-font\">The medication is controversial amid claims that it lacks effectiveness and causes adverse drug reactions, which forced the Food and Drug administration to require for a better label in 2014 that stated the risks.\u00a0\u00a0<\/p>\n<p class=\"mol-para-with-font\">Experts analyzed the medication and what prevalent symptoms it caused for the user.\u00a0<\/p>\n<p class=\"mol-para-with-font\">They found that montelukast caused an increase in nightmares and mental health issues for children, which they said should be warned by doctors when the medication is prescribed. \u00a0<\/p>\n<p>        <img loading=\"lazy\" decoding=\"async\" id=\"i-19e2305a8f4b4f28\" src=\"image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" height=\"452\" width=\"634\" alt=\"Montelukast is a drug used to help with asthma. It has caused problems for patients because of adverse drug reactions people experience. Researchers analyzed the drug and found it was more likely to increase nightmares and depression in children and adults (file photo)\" class=\"blkBorder img-share\" \/><\/p>\n<p>    <img loading=\"lazy\" decoding=\"async\" id=\"i-19e2305a8f4b4f28\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/09\/21\/16\/448E817200000578-0-image-a-1_1506009533608.jpg\" height=\"452\" width=\"634\" alt=\"Montelukast is a drug used to help with asthma. It has caused problems for patients because of adverse drug reactions people experience. Researchers analyzed the drug and found it was more likely to increase nightmares and depression in children and adults (file photo)\" class=\"blkBorder img-share\" \/><\/p>\n<p class=\"imageCaption\">Montelukast is a drug used to help with asthma. It has caused problems for patients because of adverse drug reactions people experience. Researchers analyzed the drug and found it was more likely to increase nightmares and depression in children and adults (file photo)<\/p>\n<p class=\"mol-para-with-font\">Researchers from the University of Groningen, Netherlands, analyzed the adverse drug reactions of montelukast on adults and children.<\/p>\n<p class=\"mol-para-with-font\">This drug is considered a &#8216;blockbuster&#8217; medication because it has sold more than $5 billion in medication worldwide every year.\u00a0<\/p>\n<p class=\"mol-para-with-font\">And about nine million people in the United States used the drug from 2012 to 2014.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Reactions towards montelukast were reported to the Netherlands Pharmacovigilance Center Lareb and the World Health Organization&#8217;s (WHO) Global database.<\/p>\n<ul class=\"rotator-panels link-bogr1 linkro-ccox\">\n<li>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/09\/20\/16\/44848EB500000578-0-image-m-31_1505922948547.jpg\" width=\"62\" height=\"60\" \/><span>Exposing your child to pets and germs at an early age&#8230;<\/span><br \/>\n<\/a><\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/09\/19\/22\/447D7DFC00000578-0-image-a-25_1505855143074.jpg\" width=\"62\" height=\"60\" \/><span>&#8216;I&#8217;m ALLERGIC to exercise&#8217;: Mother-of-two describes how just&#8230;<\/span><br \/>\n<\/a><\/p>\n<\/li>\n<\/ul>\n<p class=\"mol-para-with-font\">The researchers found a high amount of patients in the database who reported having allergic granulomatous angiitis, an extremely rare autoimmune disease.<\/p>\n<p class=\"mol-para-with-font\">This disease causes inflammation in the small and medium-sized blood vessels in the respiratory system.\u00a0<\/p>\n<p class=\"mol-para-with-font\">It can cause heart disease and kidney damage in its most severe stage.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Eight patients in the Netherlands hospital and 563 people in the WHO database reported having allergic granulomatous angiitis to the drug.<\/p>\n<h3 class=\"mol-factbox-title\">Montelukast and the debate on its risks<\/h3>\n<p class=\"mol-para-with-font\">Almost nine million people used montelukast, which is sold in the US as Singulair, from 2012 to 2014 in the United States.<\/p>\n<p class=\"mol-para-with-font\">This popular drug has generated more than $5 billion in sales since its inception in 1998.<\/p>\n<p class=\"mol-para-with-font\">It is used to help treat asthma symptoms for children and adults.\u00a0<\/p>\n<p class=\"mol-para-with-font\">But it has had some issues with the Food and Drug Administration after four deaths were linked to the drug.\u00a0<\/p>\n<p class=\"mol-para-with-font\">In 2014, the FDA presented concerns about the safety of the drug and its psychological changes on people who take it.<\/p>\n<p class=\"mol-para-with-font\">In the drug&#8217;s clinical trials, some people left because they felt a worsening of their asthma and breathing problems.\u00a0<\/p>\n<p class=\"mol-para-with-font\">But the drug was still approved by the FDA.\u00a0<\/p>\n<p class=\"mol-para-with-font\">The organization now requires for the drug to make it more clear on the label that there are potential neurological risks when taking it.<\/p>\n<p class=\"mol-para-with-font\">But critics say these risks are still not apparent to those who use the drug.\u00a0<\/p>\n<p class=\"mol-para-with-font\">The connection between allergic granulomatous angiitis and montelukast was not clear before this study.\u00a0<\/p>\n<p class=\"mol-para-with-font\">But the researchers said that most people didn&#8217;t have any symptoms of the rare autoimmune disease until they started taking the medication.\u00a0<\/p>\n<p class=\"mol-para-with-font\">This leads them to believe the drug is a trigger for the autoimmune disease. \u00a0<\/p>\n<p class=\"mol-para-with-font\">Also, the researchers found people were more susceptible to neurological health problems such as depression and nightmares.<\/p>\n<p class=\"mol-para-with-font\">In a recent study, 24 people who took the drug (17 children and seven adults) experienced nightmares.\u00a0<\/p>\n<p class=\"mol-para-with-font\">They nightmares ceased for 21 of the people once they stopped taking montelukast.\u00a0<\/p>\n<p class=\"mol-para-with-font\">These results were replicated after the researchers analyzed both the WHO database and patients who reported back to the\u00a0Netherlands Pharmacovigilance Center Lareb.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Nightmares became more prevalent for both children and adults until they stopped taking the drug.\u00a0<\/p>\n<p class=\"mol-para-with-font\">It has been established that asthma symptoms are associated with depression and a lower quality of life.\u00a0<\/p>\n<p class=\"mol-para-with-font\">This means that in some cases, the\u00a0adverse effect is not a result of the drug but merely a result of unresolved asthma.<\/p>\n<p class=\"mol-para-with-font\">\n<p class=\"mol-para-with-font\">But the increase in symptoms of depression is something that researchers say needs to be analyzed more to see if the drug is a contributor.\u00a0<\/p>\n<p class=\"mol-para-with-font\">They recommend for doctors to pay attention to the potential risks of montelukast and to make their patients aware of them before prescribing the medication. \u00a0<\/p>\n<p class=\"mol-para-with-font\">&#8216;Because of the high incidence of neuropsychiatric symptoms &#8211; especially nightmares &#8211; after using montelukast in both children and adults, the clinician should discuss the possibility of these adverse events with the patient and parents,&#8217; said Meindina Haarman, lead author of the study.\u00a0<\/p>\n<p>            <!-- ad: 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Your details from Facebook will be used to provide you with tailored content, marketing and ads in line with our Privacy Policy<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Montelukast, sold in the US as Singulair, is a drug that helps manage asthma symptoms Researchers from the University of Groningen, Netherlands, analyzed the adverse reactions people experience from the drug\u00a0 Patients have reported an increase in depression and nightmares\u00a0 They say doctors should be more clear about the risks when prescribing it to patients <a class=\"read-more-link\" href=\"http:\/\/healthmedicinet.com\/i\/asthma-medication-cause-nightmares-and-depression\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-201298","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/201298","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/comments?post=201298"}],"version-history":[{"count":0,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/201298\/revisions"}],"wp:attachment":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/media?parent=201298"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/categories?post=201298"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/tags?post=201298"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}