{"id":205400,"date":"2017-10-19T14:07:25","date_gmt":"2017-10-19T14:07:25","guid":{"rendered":"http:\/\/healthmedicinet.com\/i\/injection-may-help-people-lose-10-of-their-weight\/"},"modified":"2017-10-19T14:07:25","modified_gmt":"2017-10-19T14:07:25","slug":"injection-may-help-people-lose-10-of-their-weight","status":"publish","type":"post","link":"http:\/\/healthmedicinet.com\/i\/injection-may-help-people-lose-10-of-their-weight\/","title":{"rendered":"Injection may help people lose 10% of their weight"},"content":{"rendered":"<ul class=\"mol-bullets-with-font\">\n<li class=\"\"><strong>Infection could prevent type 2 diabetes by improving blood glucose levels<\/strong><\/li>\n<li class=\"\"><strong>Past research reveals a protein in the jab releases appetite-suppressant signals<\/strong><\/li>\n<li class=\"\"><strong>Obesity medications cause a maximum body weight loss of 12% after one year<\/strong><\/li>\n<li class=\"\"><strong>Bariatric surgery makes people lose up to 30% of their body weight but is risky<\/strong><\/li>\n<li class=\"\"><strong>The injection has no side effects in monkeys but needs replicating in humans \u00a0<\/strong><\/li>\n<\/ul>\n<p class=\"author-section byline-plain\">By<\/p>\n<p>Alexandra Thompson Health Reporter For Mailonline<\/a><\/p>\n<p class=\"byline-section\"><span class=\"article-timestamp article-timestamp-published\"><br \/>\n  <span class=\"article-timestamp-label\">Published:<\/span><br \/>\n  09:44 EDT, 19 October 2017<br \/>\n<\/span><br \/>\n | <span class=\"article-timestamp article-timestamp-updated\"><br \/>\n  <span class=\"article-timestamp-label\">Updated:<\/span><br \/>\n  09:44 EDT, 19 October 2017<br \/>\n<\/span>\n<\/p>\n<\/p>\n<ul>\n<li class=\"share-facebook\"><\/li>\n<li class=\"share-twitter\"><\/li>\n<li class=\"share-pinterest\"><\/li>\n<li class=\"share-gplus\">\n      <span class=\"g-interactivepost\"><br \/>\n        <a><\/a><br \/>\n      <\/span>\n        <\/li>\n<li class=\"share-email\">\n<p>                <span class=\"wai\">e-mail<\/span><br \/>\n            <\/a>\n        <\/li>\n<li class=\"share-icons\" id=\"shareLinkTop\">\n            <\/a>\n            <\/li>\n<\/ul>\n<p> <span><\/span><\/p>\n<p class=\"count-number\">           1<\/p>\n<p class=\"count-text\">View <br \/> comments<\/p>\n<p>    <\/a><\/p>\n<p class=\"mol-para-with-font\">A hunger-blocking jab could help people lose 10 percent of their body weight in six weeks, new research reveals.\u00a0<\/p>\n<p class=\"mol-para-with-font\">When injected with a specific protein, known as GDF15, obese monkeys lose this amount of weight in just\u00a0six weeks, as well as their appetite being suppressed by 40 percent, a US study found.<\/p>\n<p class=\"mol-para-with-font\">The animals&#8217; glucose levels also improve after jab administration, which lowers their risk of developing type 2 diabetes, the research adds.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Although research has only been conducted in animals to date, the findings raise hope of one combating obesity in humans. \u00a0<\/p>\n<p class=\"mol-para-with-font\">Previous studies reveal GDF15 binds to molecules in the stomach and intestines, which causes signals to be sent to the brain that reduce appetite without causing side effects.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Obesity is an epidemic in the western world, affecting up to one-third of the population of the US and UK.<\/p>\n<p class=\"mol-para-with-font\">Weight-loss medications generally cause people to lose between seven and 12 percent of their body weight after a year, while bariatric surgery peaks at 30 percent weight loss but is expensive and can result in hernias, bowel obstruction and malnutrition.<\/p>\n<p>        <img loading=\"lazy\" decoding=\"async\" id=\"i-2a005a77dc57bfa8\" src=\"image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" height=\"420\" width=\"634\" alt=\"A hunger-blocking injection could help people lose 10 percent of their body weight in weeks\" class=\"blkBorder img-share\" \/><\/p>\n<p>    <img loading=\"lazy\" decoding=\"async\" id=\"i-2a005a77dc57bfa8\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/10\/19\/13\/457DFF7500000578-4996652-image-a-1_1508414614280.jpg\" height=\"420\" width=\"634\" alt=\"A hunger-blocking injection could help people lose 10 percent of their body weight in weeks\" class=\"blkBorder img-share\" \/><\/p>\n<p class=\"imageCaption\">A hunger-blocking injection could help people lose 10 percent of their body weight in weeks<\/p>\n<ul class=\"rotator-panels link-bogr1 linkro-ccox\">\n<li>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/10\/19\/10\/457C292A00000578-0-image-m-19_1508405410454.jpg\" width=\"62\" height=\"60\" \/><span>The girl who can SMELL colours: 11-year-old possesses the&#8230;<\/span><br \/>\n<\/a><\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/10\/19\/10\/457BFE8500000578-0-image-a-33_1508405355847.jpg\" width=\"62\" height=\"60\" \/><span>The two-year-old girl paralysed by painful arthritis: Mother&#8230;<\/span><br \/>\n<\/a><\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/10\/19\/00\/183C18E100000514-0-image-a-15_1508368026996.jpg\" width=\"62\" height=\"60\" \/><span>Hundreds of women are dying needlessly each year because the&#8230;<\/span><br \/>\n<\/a><\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2017\/10\/19\/09\/457C327500000578-0-image-a-6_1508402581927.jpg\" width=\"62\" height=\"60\" \/><span>Rise of the randy pensioners: One in five OAPS believe they&#8230;<\/span><br \/>\n<\/a><\/p>\n<\/li>\n<\/ul>\n<h3 class=\"mol-factbox-title\">INTERMITTENT FASTING CAN CAUSE WEIGHT LOSS IN WEEKS BY STIMULATING CELLS TO BURN FAT\u00a0<\/h3>\n<p class=\"mol-para-with-font\">Intermittent fasting can cause substantial weight loss in just weeks, research revealed earlier this month.<\/p>\n<p class=\"mol-para-with-font\">Mice who are fed a normal diet for two days followed by 24 hours without food shed pounds after just six weeks, a study found.<\/p>\n<p class=\"mol-para-with-font\">Researchers believe fasting triggers a protein that causes white blood cells to stimulate fat cells to burn lipids.<\/p>\n<p class=\"mol-para-with-font\">Study author Professor Kyoung-Han Kim from The Hospital for Sick Children in Ontario, said: &#8216;Intermittent fasting without a reduction in calorie intake can be a preventative and therapeutic approach against obesity and metabolic disorders.&#8217;<\/p>\n<p class=\"mol-para-with-font\">Previous research reveals fasting reduces abdominal fat, which is linked to an increased risk of type 2 diabetes, heart disease and certain cancers.<\/p>\n<p class=\"mol-para-with-font\">As well as weight loss, extreme calorie restriction has also been associated with improved blood pressure, gut health and brain function.\u00a0<\/p>\n<p class=\"mol-para-with-font\">\n<p class=\"mol-para-with-font\"><span class=\"mol-style-medium health-ccox mol-style-bold\">Reduces body weight by 10% in six weeks\u00a0<\/span><\/p>\n<p class=\"mol-para-with-font\">Researchers based in Amgen&#8217;s LA office injected obese monkeys with GDF15, as well as an antibody to make the protein circulate longer in the body.<\/p>\n<p class=\"mol-para-with-font\">Results reveal the monkeys lost 10 percent of their body weight  and ate around 40 per cent less after six weeks.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Their blood glucose levels also improved, which reduces the risk of developing type 2 diabetes.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Previous research in mice shows GDF15 binds to molecules in the stomach and intestines, which causes signals to be sent to the brain that reduces appetite.<\/p>\n<p class=\"mol-para-with-font\"><span class=\"mol-style-medium health-ccox mol-style-bold\">More effective than approved medications \u00a0<\/span><\/p>\n<p class=\"mol-para-with-font\">Obesity is a troubling epidemic in the western world, affecting up to one-third of the adult population of the US and UK.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Carrying too much weight puts people at risk of heart disease, stroke and certain cancers. \u00a0<\/p>\n<p class=\"mol-para-with-font\">FDA-approved obesity medications tend to cause people to lose between seven and 12 percent of their body weight after a year&#8217;s administration.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Yet drugs such as Roche&#8217;s Xenical have been linked to incontinence, diarrhoea and flatulence. \u00a0<\/p>\n<p class=\"mol-para-with-font\">Although  bariatric surgery is the gold-standard weight-loss treatment as it causes between 20 and 30 per cent body weight loss, it is expensive and can cause complications including bowel obstruction, hernias and malnutrition.<\/p>\n<p class=\"mol-para-with-font\">According to the study&#8217;s lead author Murielle V\u00e9niant, the injection caused no side effects in monkeys but needs replicating in humans.<\/p>\n<p class=\"mol-para-with-font\">The findings were published in the journal Science Translational Medicine.\u00a0<\/p>\n<p>            <!-- ad: http:\/\/mads.dailymail.co.uk\/v3\/us\/health\/none\/article\/other\/inread_player.html --><\/p>\n<h3 class=\"social-links-title\">Share or comment on this article<\/h3>\n<ul class=\"bigLinks sc-icns cleared\">\n<li class=\"share-facebook\">\n<p>                                    <span class=\"wai\">e-mail<\/span><br \/>\n                                <\/a>\n                            <\/li>\n<li class=\"share-icons\" id=\"shareLinkBottom\">\n<p>                                <\/a>\n                            <\/li>\n<li id=\"addCommentButton\" class=\"add-comment\">\n<p>                            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Your details from Facebook will be used to provide you with tailored content, marketing and ads in line with our Privacy Policy<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Infection could prevent type 2 diabetes by improving blood glucose levels Past research reveals a protein in the jab releases appetite-suppressant signals Obesity medications cause a maximum body weight loss of 12% after one year Bariatric surgery makes people lose up to 30% of their body weight but is risky The injection has no side <a class=\"read-more-link\" href=\"http:\/\/healthmedicinet.com\/i\/injection-may-help-people-lose-10-of-their-weight\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-205400","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/205400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/comments?post=205400"}],"version-history":[{"count":0,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/205400\/revisions"}],"wp:attachment":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/media?parent=205400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/categories?post=205400"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/tags?post=205400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}