{"id":96935,"date":"2016-07-22T12:53:32","date_gmt":"2016-07-22T12:53:32","guid":{"rendered":"http:\/\/healthmedicinet.com\/i\/antibiotics-could-tackle-alzheimers\/"},"modified":"2016-07-22T12:53:32","modified_gmt":"2016-07-22T12:53:32","slug":"antibiotics-could-tackle-alzheimers","status":"publish","type":"post","link":"http:\/\/healthmedicinet.com\/i\/antibiotics-could-tackle-alzheimers\/","title":{"rendered":"Antibiotics could tackle Alzheimer&#8217;s"},"content":{"rendered":"<ul class=\"mol-bullets-with-font\">\n<li class=\"\"><strong>When US scientists gave some mice a cocktail of common antibiotics, levels of a brain protein that is a hallmark of Alzheimer\u2019s began to plummet<\/strong><\/li>\n<li class=\"\"><strong>Antibiotics fought the disease by killing some bugs in the animals\u2019 guts\u00a0<\/strong><\/li>\n<li class=\"\"><strong>This had a knock-on effect on the immune system, giving it a big boost<\/strong><strong>\u00a0<\/strong><\/li>\n<\/ul>\n<p class=\"author-section byline-plain\">By<\/p>\n<p>Fiona Macrae Science Correspondent For The Daily Mail<\/a><\/p>\n<p class=\"byline-section\"><span class=\"article-timestamp article-timestamp-published\"><br \/>\n  <span class=\"article-timestamp-label\">Published:<\/span><br \/>\n  18:56 EST, 21 July 2016<br \/>\n<\/span><br \/>\n | <span class=\"article-timestamp article-timestamp-updated\"><br \/>\n  <span class=\"article-timestamp-label\">Updated:<\/span><br \/>\n  01:54 EST, 22 July 2016<br \/>\n<\/span>\n<\/p>\n<\/p>\n<ul>\n<li class=\"share-facebook\"><\/li>\n<li class=\"share-twitter\"><\/li>\n<li class=\"share-pinterest\"><\/li>\n<li class=\"share-gplus\">\n      <span class=\"g-interactivepost\"><br \/>\n        <a><\/a><br \/>\n      <\/span>\n    <\/li>\n<li class=\"share-email\">\n    <\/a>\n      <\/li>\n<\/ul>\n<p>   <span><\/span><\/p>\n<p class=\"count-number\">          33<\/p>\n<p class=\"count-text\">View <br \/> comments<\/p>\n<p>  <\/a><\/p>\n<p class=\"mol-para-with-font\">Antibiotics could hold the key to beating Alzheimer\u2019s disease.<\/p>\n<p class=\"mol-para-with-font\">When scientists gave mice a cocktail of common antibiotics, levels of a brain protein that is a hallmark of Alzheimer\u2019s plummeted.<\/p>\n<p class=\"mol-para-with-font\">It is thought that antibiotics fought the disease by killing some bugs in the animals\u2019 guts, allowing others to thrive.<\/p>\n<p class=\"mol-para-with-font\">This had a knock-on effect on the immune system, giving it the boost it needed to protect the brain.<\/p>\n<p class=\"mol-para-with-font\"><span class=\"mol-style-bold\">Scroll down for video\u00a0<\/span><\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" id=\"i-87c9e99989f2670b\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/22\/00\/03541E17000003E8-0-image-a-40_1469145167072.jpg\" height=\"421\" width=\"634\" alt=\"When scientists gave mice a cocktail of common antibiotics, levels of a brain protein that is a hallmark of Alzheimer\u2019s plummeted\" class=\"blkBorder img-share\" \/>    <\/p>\n<p class=\"imageCaption\">When scientists gave mice a cocktail of common antibiotics, levels of a brain protein that is a hallmark of Alzheimer\u2019s plummeted<\/p>\n<p class=\"mol-para-with-font\">While the idea that tummy bugs affect the brain might seem bizarre, the trillions of bacteria that naturally live in the gut are beginning to be linked to conditions from autism to multiple sclerosis.<\/p>\n<p class=\"mol-para-with-font\">US researcher Sangram Sisodia, said: \u2018We are exploring very new territory in how the gut influences brain health.<\/p>\n<p class=\"mol-para-with-font\">\u2018This is an area that people who work with neurodegenerative diseases are going to be increasingly interested in, because it could have an influence down the road on treatments.\u2019<\/p>\n<p class=\"mol-para-with-font\">Dr Sisodia, of the University of Chicago, began by comparing the guts of mice given antibiotics for six months with that of untreated creatures.<\/p>\n<p class=\"mol-para-with-font\">Both groups had the same number of bacteria \u2013 but from vastly different strains.<\/p>\n<p class=\"mol-para-with-font\">He then looked at the animals\u2019 brains.<\/p>\n<p class=\"mol-para-with-font\">All of the mice were from a breed prone to Alzheimer\u2019s and should have had lots of the sticky protein plaques that clog up the brains of human patients.<\/p>\n<p class=\"mol-para-with-font\">But the mice given the antibiotics had half as much of the poisonous protein, suggesting the disease had developed more slowly.<\/p>\n<p class=\"mol-para-with-font\">It is thought that chemicals produced by the bugs in our guts affect the immune system.<\/p>\n<p class=\"mol-para-with-font\">By changing the bugs, the antibiotics changed the chemicals, making it easier for the immune clear away the poisonous Alzheimer\u2019s protein.<\/p>\n<p>  <img loading=\"lazy\" decoding=\"async\" id=\"i-6e00aea691810411\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/22\/00\/037B453F000003E8-0-image-a-41_1469145190593.jpg\" height=\"424\" width=\"634\" alt=\"While the idea that tummy bugs affect the brain might seem bizarre, the trillions of bacteria that naturally live in the gut are beginning to be linked to conditions from autism to multiple sclerosis\" class=\"blkBorder img-share\" \/>    <\/p>\n<p class=\"imageCaption\">While the idea that tummy bugs affect the brain might seem bizarre, the trillions of bacteria that naturally live in the gut are beginning to be linked to conditions from autism to multiple sclerosis<\/p>\n<p class=\"mol-para-with-font\">The find, detailed in the journal Scientific Reports, could lead to much-needed new treatments for Alzheimer\u2019s.<\/p>\n<p class=\"mol-para-with-font\">Researcher Myles Minter said: \u2018We don\u2019t propose that a long-term course of antibiotics is going to be a treatment \u2013 that\u2019s just absurd for a whole number of reasons.<\/p>\n<p class=\"mol-para-with-font\">\u2018But what this study does is allow us to explore further, now that we&#8217;re clearly changing the gut microbial population and have new bugs that are more prevalent in mice with altered amyloid deposition after antibiotics.\u2019<\/p>\n<p class=\"mol-para-with-font\">Possibilities include drugs based on the chemicals made by the bugs \u2013 or even possibly probiotics packed with brain-friendly bacteria.<\/p>\n<p class=\"mol-para-with-font\">Dr Sisodia said; \u2018I don\u2019t know about probiotics but if you could find the right types of bacteria that protect brain health, there may be something there.\u2019\u00a0<\/p>\n<p class=\"mol-para-with-font\">\n<h3 class=\"social-links-title\">Share or comment on this article<\/h3>\n<ul class=\"bigLinks sc-icns cleared\">\n<li class=\"facebook\">\n<p>              <\/a>\n            <\/li>\n<li class=\"social-stats social-stats-pipe\" id=\"shareCountBottom\">\n<\/li>\n<li 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of Alzheimer\u2019s began to plummet Antibiotics fought the disease by killing some bugs in the animals\u2019 guts\u00a0 This had a knock-on effect on the immune system, giving it a big boost\u00a0 By Fiona Macrae Science <a class=\"read-more-link\" href=\"http:\/\/healthmedicinet.com\/i\/antibiotics-could-tackle-alzheimers\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-96935","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/96935","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/comments?post=96935"}],"version-history":[{"count":0,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/posts\/96935\/revisions"}],"wp:attachment":[{"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/media?parent=96935"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/categories?post=96935"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/healthmedicinet.com\/i\/wp-json\/wp\/v2\/tags?post=96935"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}