{"id":60278,"date":"2016-12-22T00:59:58","date_gmt":"2016-12-22T00:59:58","guid":{"rendered":"http:\/\/healthmedicinet.com\/news\/for-young-kids-ear-infections-longer-antibiotic-treatment-works-better\/"},"modified":"2016-12-22T00:59:58","modified_gmt":"2016-12-22T00:59:58","slug":"for-young-kids-ear-infections-longer-antibiotic-treatment-works-better","status":"publish","type":"post","link":"http:\/\/healthmedicinet.com\/news\/for-young-kids-ear-infections-longer-antibiotic-treatment-works-better\/","title":{"rendered":"For Young Kids\u2019 Ear Infections, Longer Antibiotic Treatment Works Better"},"content":{"rendered":"<p>    <img decoding=\"async\" src=\"https:\/\/media.npr.org\/assets\/img\/2016\/12\/20\/gettyimages-184860935-93b37b4143548775e3d0e823c418c0ccf212d11d-s1100-c15.jpg\" class=\"img lazyOnLoad\" alt=\"Ear infections are common in young children, and often treated with antibiotics.\" \/><\/p>\n<p>        <img alt=\"Ear infections are common in young children, and often treated with antibiotics.\" \/><\/p>\n<p>Researchers looking into whether a shorter course of antibiotics would treat young children\u2019s ear infections as well as a longer course, found that not only was the shorter treatment less effective, it didn\u2019t reduce antibiotic resistance or side effects.<\/p>\n<p>The study, published Wednesday in the <em>New England Journal of Medicine<\/em>, comes as physicians and researchers are trying to come up with ways to curb the unnecessary use of antibiotics, including the possibility of using them for a shorter time against some common infections. The goal is to prevent bacteria from developing resistance to antibiotics. While that strategy didn\u2019t pan out in this particular study, shorter antibiotic courses are still being used and studied in other contexts.<\/p>\n<p>                  <img decoding=\"async\" src=\"https:\/\/media.npr.org\/assets\/img\/2013\/02\/22\/ap061120047677_sq-ae00c34bc89f659bc456aba07dbb0fe509a46fa5-s100-c15.jpg\" class=\"img lazyOnLoad\" alt=\"Pediatricians Urged To Treat Ear Infections More Cautiously\" \/><\/p>\n<p><!-- END CLASS=\"BUCKETBLOCK\" --><\/p>\n<p><!-- END CLASS=\"BUCKET IMG\" --><\/p>\n<p><!-- END ID=\"RES506444023\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The study included 520 children between 6 and 23 months old who were diagnosed with an acute middle ear infection, a very common childhood illness. Half of the children were randomly assigned to receive 10 days of the antibiotic amoxicillin-clavulanate, while the other half received 5 days of the drug plus another five days of a placebo. If the children experienced another ear infection during the period they were in the study, they received the same treatment. Parents, researchers and clinicians didn\u2019t know what treatment a child was getting.<\/p>\n<p>The kids were tracked for the severity of their symptoms and had regular office visits to check their health, plus additional visits if they were ill. The researchers also checked to see if their throats had been colonized by bacteria that were resistant to the antibiotic.<\/p>\n<p>The researchers found that initial treatment failed in 34 percent of the children treated with the five days of antibiotics, compared to 16 percent of children who had the longer treatment. Symptoms were also worse in the group that received the shorter treatment regimen. And there was no difference between the groups in the rate of colonization with antibiotic-resistant bacteria.<\/p>\n<aside id=\"ad-backstage-wrap\"><\/aside>\n<aside id=\"ad-mobilebackfill-wrap\"><\/aside>\n<p>The results were a surprise, says Dr. Alejandro Hoberman, chief of the division of general academic pediatrics at Children\u2019s Hospital of Pittsburgh and an author of the study. \u201cI also expected that if you used an antibiotic for a shorter period of time, there would be fewer adverse events,\u201d he says. But that didn\u2019t happen; rates of diarrhea and diaper rash, both of which are side effects of antibiotics, were similar in both groups.<\/p>\n<p>The authors said the findings can\u2019t be generalized to children who are older than two years, or to adults.<\/p>\n<p>A 2010 Cochrane Review of research found that using antibiotics for less than seven days increased the likelihood of treatment failure. But Hoberman says many of the previous trials had some flaws, including less strict diagnostic criteria. This study was designed to address those gaps.<\/p>\n<p>\u201cThis study really shows the importance of doing clinical trials,\u201d says Dr. Helen Boucher, an infectious disease specialist at Tufts Medical Center and a member of the board of the Infectious Diseases Society of America (IDSA.) There\u2019s a push to see if the optimal dose of antibiotics could be shortened in some contexts, but that has to be studied with specific combinations of infections, antibiotics and patient populations, she says. \u201cThe whole notion of really figuring out the optimal duration of therapy is one we\u2019ve been advocating heavily for.\u201d<\/p>\n<p>For example, a study of a shorter course of antibiotics against urinary tract infections in children is ongoing. And based on the existing research, the IDSA and the American Thoracic Society recommended earlier this year that most patients who develop pneumonia in the hospital receive a short course of antibiotics.<\/p>\n<p>Another prong of the strategy is to limit the use of antibiotics to bacterial infections, says Dr. Pranita Tamma, a pediatrician and director of the pediatric antimicrobial stewardship program at the Johns Hopkins University School of Medicine. Parents often come to the doctor when their kids have upper respiratory infections, but most of those are colds caused by a virus and can\u2019t be helped by antibiotics. A 2014 study found that displaying posters in exam stating the clinicians\u2019 commitment to avoid unnecessary antibiotic prescriptions for upper respiratory infections lowered the rate of inappropriate prescriptions.<\/p>\n<p>\u201cAntibiotics can be life-saving when used properly,\u201d says Tamma. \u201cBut every day that an antibiotic is used, whether it\u2019s indicated or not, can put you at additional risk.\u201d<\/p>\n<p><em>Katherine Hobson is a freelance health and science writer based in Brooklyn, N.Y. She\u2019s on Twitter: <\/em><em>@katherinehobson<\/em><em>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers looking into whether a shorter course of antibiotics would treat young children\u2019s ear infections as well as a longer course, found that not only was the shorter treatment less effective, it didn\u2019t reduce antibiotic resistance or side effects. The study, published Wednesday in the New England Journal of Medicine, comes as physicians and researchers [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-60278","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts\/60278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/comments?post=60278"}],"version-history":[{"count":0,"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts\/60278\/revisions"}],"wp:attachment":[{"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/media?parent=60278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/categories?post=60278"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/tags?post=60278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}