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Vitamin C could diminution post-operative AF in cardiac medicine patients


AF is a common cardiac cadence reeling that can lead to serious consequences such as cadence and heart failure. AF can be triggered by several stressful conditions and about 30% of patients undergoing cardiac operations humour from post-operative AF.

Harri Hemilä from a University of Helsinki, Finland, and Timo Suonsyrjä from a Helsinki University Central Hospital, Finland, carried out a systematic examination of vitamin C for preventing AF in high risk patients. They identified 14 randomized trials totaling 2006 patients who had undergone cardiac surgery, and one hearing with 44 patients that had investigated a regularity of AF after a successful cardioversion.

There was estimable heterogeneity between a 14 cardiac medicine trials, though a heterogeneity was explained by a multiplication of them between 5 trials carried out in a USA and 9 trials conducted outward of a USA. The 5 cardiac medicine trials carried out in a USA regularly found no outcome of vitamin C opposite post-operative AF. In contrast, a 9 cardiac medicine trials conducted outward of a USA found a meant rebate of 44% in a occurrence of post-operative AF and there was no heterogeneity between these 9 trials. Five of a latter trials were carried out in Iran, dual in Greece, one in Slovenia and one in Russia.

The singular investigate on a regularity of AF after a successful cardioversion, that was carried out in Greece, found that vitamin C decreased a risk of AF regularity by 87%.

In a non-US cardiac medicine trials, vitamin C decreased a length of sanatorium stay by 12.6% and complete caring section stay by 8.0%.

Some of a medicine patients in a non-US studies were administered vitamin C orally, since in others vitamin C was administered intravenously. The latter track leads to almost aloft levels of vitamin C in a blood, so a effects of a dual administration methods competence differ.

Oral administration of vitamin C decreased a occurrence of post-operative AF by 73%, since intravenous administration decreased it by 36%. On a other hand, verbal administration condensed a length of sanatorium stay by usually 7% (0.4 days), since intravenous administration decreased it by 16% (1.5 days). Thus, a outcome of intravenous vitamin C administration was larger for a length of sanatorium stay, though reduction for a occurrence of post-operative AF.

According to Drs. Hemilä and Suonsyrjä, “Vitamin C is a protected low-cost essential nutrient. Given a unchanging justification from a reduction rich countries, vitamin C competence be administered to cardiac medicine patients, nonetheless serve studies are indispensable to find out optimal protocols for a administration. However, there seems to be no motive for serve investigate of unselected patients in rich countries, though a effects of vitamin C for patients who have a quite low documented turn of vitamin C competence still be worthwhile.”

University of Helsinki