Older adults’ driving habits reveal clues about their brain health and may provide early warning signs of cognitive decline or dementia, according to a preliminary study presented at the American Stroke Association’s International Stroke Conference 2026, held in New Orleans, Feb. 4–6, 2026.
“Driving habits in older adults can reveal early changes in brain health. How often people drive, where they go, and how much they vary their routes may signal underlying damage to the brain’s white matter, which is linked to cognitive decline and dementia,” said study author Chia-Ling Phuah, M.D., M.M.Sc., an associate professor of neurocritical care and co-director of the Neuro Analytics Center at Barrow Neurological Institute in Phoenix.
“These findings suggest that even small shifts in daily driving patterns can offer important clues about brain changes—sometimes before traditional memory and thinking symptoms are noticeable.”
According to the American Heart Association 2026 Heart and Stroke Statistics, about 6.9 million (10.9%)—or one in nine—adults 65 years or older in the United States were living with Alzheimer’s disease in 2024.
Researchers reviewed driving habits for 220 adult volunteers, ages 65 and older, living independently in St. Louis, Missouri. Detailed cognitive assessments indicated participants were free of dementia at the start of the study.
Car sensors were used to track participants’ driving behavior (including speeding, collisions, hard braking or hard cornering) for more than five years. They conducted additional brain imaging studies within the first year of the study to measure changes in the brain’s white matter, specifically white matter hyperintensities—areas of white matter damage caused by reduced blood flow to brain tissue.
The analysis found:
- Older adults who had more white matter hyperintensities tended to drive less and show sharper declines in their willingness or ability to change driving routes and habits.
- Over more than five years of follow-up, 17% of participants developed cognitive impairment and most of these individuals were later diagnosed with Alzheimer’s disease.
- Among the 17% of participants who developed cognitive impairment, higher white matter hyperintensity burden on brain imaging was linked to a greater likelihood of unsafe driving practices, such as hard braking, and to more crashes.
- “Participants with white matter hyperintensities located in the back of the brain—a region responsible for processing what people see and how they move—were at even higher risk of crashes than those with changes in other brain areas, making them more likely to experience unsafe driving episodes and car accidents over time,” Phuah explained.
- Participants taking medications to manage high blood pressure, especially angiotensin-converting enzyme (ACE) inhibitors, were less likely to exhibit risky driving when compared with those who were not taking any blood pressure medication.
Overall, the study’s findings suggest that monitoring driving behavior with commercial in-vehicle data loggers may help identify older adults at higher risk for unsafe driving, loss of independence and subtle cognitive problems, Phuah noted.
“One especially promising finding was that people taking blood pressure medications, particularly ACE inhibitors, tended to maintain safer driving habits even when their brain scans revealed more damage. This effect was observed regardless of whether their blood pressure levels were at target levels,” Phuah said. “This suggests that these medications may help support brain health as we age.”
Nada El Husseini, M.D., M.H.Sc., FAHA, chair of the American Heart Association’s 2023 scientific statement, Cognitive Impairment After Ischemic and Hemorrhagic Stroke said, “What’s surprising about these findings is that people taking ACE inhibitors were less likely to have impairment in their driving despite the extent of white matter disease. The impact of ACE inhibitors on cognitive function and driving safety in people with white matter disease requires further investigation. Also, these results suggest cognitive screening and brain imaging might be considered for people with driving difficulties.”
El Husseini is an associate professor of neurology at Duke University Medical Center in Durham, North Carolina and was not involved in this study.
Normal blood pressure is less than 120/80, and treatment is recommended for people with blood pressure levels of 140/90 mm Hg or higher (stage 2 hypertension). Recent research confirms that blood pressure affects brain health, including cognitive function and dementia, so early treatment is recommended for people diagnosed with high blood pressure to maintain brain health and cognition, according to the 2025 American Heart Association High Blood Pressure Guideline.
Key limitations include a small study size, most participants were white, college-educated adults, so results may not generalize to people from more diverse backgrounds, and medication use was self-reported, which could introduce errors.
The next step will be larger studies that include more diverse participants to confirm and extend these findings.
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