- People who had a good blood flow to smallest blood vessels lived longer
- Scientists uncovered the findings during research into Italian ‘Superagers’
- Genetics, reduced calories and exercise all play a role in keeping healthy
Rory Tingle For Mailonline
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Having a healthy blood circulation is the key to a longer life, according to new research.
Centenarians whose body could pump blood to the far reaches of muscles and organs had a circulation system as efficient as people 30 years younger.
Scientists uncovered the findings during research into Italian ‘Superagers’, who had an average age of 92.
Centenarians whose body could pump blood to the far reaches of muscles and organs had a circulation system as efficient as people 30 years younger
The body’s microcirculatory system delivers oxygen to cells while removing waste products.
This is in addition to controlling blood pressure and body temperature by constricting or dilating the capillaries that supply the muscles, skin and organs.
People who lived to one hundred showed similar levels of Bio-ADM, a chemical that boosts blood flow in the body’s capillarity networks, as people 30 years younger.
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Genetics, reduced calories, exercise and a Mediterranean diet all play a role in how long someone lives but scientists have been searching for biomarkers that may indicate longevity.
Professor Salvatore Di Somma, of La Sapienza University, said: ‘Very low concentrations of Bio-ADM indicate a well-functioning endothelial and microcirculatory system allowing good blood perfusion of organs and muscles.
‘A good microcirculation is what makes marathon runners perform better at the same heart rate than the average man or woman on the street.’
The Cilento Intitiative on Ageing Outcome pilot study looked at two groups that live in the Cilento region, located in the province of Salerno in southern Italy.
Scientists found ‘SuperAgers’ who had good blood flow to the smallest blood vessels within the body – capillaries – lived longer
Women living in the Cilento region live to an average of 92, eight years more than the Italian average, while men live to 85, six years more than the average.
The first group consisted of 29 ‘SuperAgers’ with a median age of 92.
The second was made up of 52 younger relatives with a median age of 60 living in the same household who are expected to live just as long because they have the same genetic background and same environmental and lifestyle factors.
Genetics, reduced calories, exercise and a Mediterranean diet all play a role in how long someone lives
Blood analyses measured levels of bio-ADM and two other biomarkers.
These were compared to a cohort of 194 healthy persons with a median age of 63.9 monitored over eight years in an earlier project.
In the group of SuperAgers, the bio-ADM values were as low as those in both reference groups.
Dr Andreas Bergmann, of the German diagnostic company sphingotec which carried out blood analyses, said: ‘We are excited about the connection between bio-ADM levels and a good microcirculation as an indicator for good quality of life.
‘If bio-ADM proves to be a reliable biomarker for longevity this will open up the avenue to a systematic analysis of the factors contributing to longevity.
‘We are excited to contribute to the identification of lifestyle factors ensuring a good microcirculation.’
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