Breast cancer incidence developments differ by age, even amongst older ladies, notably by race and ethnicity and stage at prognosis, in response to a review printed on-line June 24 in JAMA Network Open.
Erica J. Lee Argov, M.P.H., from the Mailman School of Public Health at Columbia University in New York City, and colleagues carried out a cross-sectional study wherein they disaggregated U.S. breast cancer incidence developments amongst older ladies (aged 65 to 74, 75 to 84, and 85 years and older) in response to stage at prognosis, race and ethnicity, hormone receptor subtype, and geography. The evaluation included knowledge from roughly 2.3 million ladies identified with breast cancer from 2001 by way of 2019.
The researchers discovered that age-adjusted breast cancer incidence charges had been 530.4, 515.3, and 376.8 per 100,000 individuals for ages 65 to 74 years, 75 to 84 years, and 85 years and older, respectively. Incidence charges elevated in ladies aged 65 to 74 years (common annual % modifications [AAPC], 0.4%), remained steady in ladies aged 75 to 84 years, and decreased in ladies aged 85 years or older (AAPC, ?1.1%). The AAPC was seven to 11 instances increased in Hispanic, non-Hispanic American Indian or Alaska Native, non-Hispanic Asian or Pacific Islander, and non-Hispanic Black ladies aged 65 to 74 years versus non-Hispanic White ladies. Regional-stage diagnoses decreased throughout all age teams (ages 65 years and older: AAPC, ?0.8%), whereas distant-stage diagnoses elevated (ages 65 years and older: AAPC, 1.3%). There was variance by age for developments for in situ and localized diagnoses. Non-Hispanic Black ladies had the best proportion of hormone receptor and ERBB2-unfavourable cancers throughout all age teams.
“The findings of this study recommend that breast cancer incidence developments amongst older ladies ought to be disaggregated by age teams to account for age-related variations in screening and different danger elements,” the authors write.
More data:
Erica J. Lee Argov et al, Breast Cancer Incidence Trends in Older US Women by Race, Ethnicity, Geography, and Stage, JAMA Network Open (2025). DOI: 10.1001/jamanetworkopen.2025.16947
Citation:
Breast cancer incidence developments differ by age ( 1)
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