
Men with excessive ranges of stomach fats are at elevated threat of dementia, in accordance with a brand new study by Monash University researchers of greater than 17,000 people aged 65 to 98 years within the ASPREE Study.
Importantly, the research additionally discovered that the chance for dementia is as much as 38% decrease in these with larger lean physique mass and, maybe surprisingly, extra fats physique mass.
The study, published in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, discovered that dementia threat was 15% to 38% decrease for people in larger quartiles of lean or fats physique mass.
Professor Joanne Ryan, who heads the Biological Neuropsychiatry and Dementia analysis unit within the School of Public Health and Preventive Medicine at Monash, was a senior creator on the research.
“Higher lean physique mass and fats physique mass in later life could also be related to higher cognition, whereas belly fats might be a threat issue, notably in males,” the research stated.
Excess physique weight, particularly in midlife, is taken into account a threat issue for quite a few well being situations, together with diabetes and heart problems, which in flip are threat elements for dementia and cancer.
“Our findings counsel that elevated physique weight in older age might confer protecting results on mind growing older, no matter physique composition. However, belly adiposity should be a threat issue for cognitive impairment in older people, notably in males,” Professor Ryan stated.
“These findings counsel that avoiding extra fats accumulation within the belly space and sustaining a stability between lean and fats mass could also be helpful to cognitive operate in older age. Lifestyle methods, corresponding to a nutritious diet and common train, probably play a task in defending mind well being for older people.”
More data:
Zimu Wu et al, Associations of belly adiposity, lean physique mass, and fats physique mass with dementia and cognitive change in older age, Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring (2025). DOI: 10.1002/dad2.70135
Citation:
Dementia safety linked to where the physique lies—stomach fats a threat issue ( 8)
10 July 2025
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