HMN 2025: How to Identify young people at risk of cardiac arrest

Chance to identify young people at risk of cardiac arrest
Distribution of symptoms in total(blue) and The American Journal of Cardiology (2025). DOI: 10.1016/j.amjcard.2025.09.062

Many young people who suffered sudden cardiac death had recently sought medical care. More frequent use of electrocardiograms (EKG) could help prevent such cases, according to researchers at the University of Gothenburg.

Sudden cardiac death without visible heart disease—known as sudden arrhythmic death– can strike even young, seemingly healthy individuals. It is, however, very rare: about 15 cases occur each year in Sweden.

In this Swedish nationwide study, researchers examined all cases of sudden arrhythmic death among individuals aged 1 to 35 who died in Sweden between 2000 and 2010. Many of those who died had shown signs of heart problems before their deaths. The findings are published in The American Journal of Cardiology.

One in three had sought medical care

The study identified 149 deaths over the 10-year period in which autopsies found no structural damage to the heart—indicating an electrical disturbance in the heart rhythm. Using Sweden’s national health and population registers along with , the researchers analyzed symptoms, EKG results, and health care visits prior to death. Each case was compared with 10 randomly selected individuals from the Swedish population, matched by age, sex, and county of residence.

Key findings

  • Most of the victims were young men in their early 20s.
  • Half had shown early warning signs such as fainting or palpitations.
  • One in three had sought within six months of death. Among these, visits for fainting were 20 times more common and visits for seizures 10 times more common than among controls.
  • Nearly one in five had a previously abnormal EKG.

EKG changes

The study was conducted by Matilda Frisk Torell, a researcher affiliated with the Sahlgrenska Academy at the University of Gothenburg and a cardiologist at Sahlgrenska University Hospital.

“It’s striking that so many had seen a doctor shortly before the event. It shows that we have an opportunity to identify those at risk before something happens,” says Frisk Torell.

The results indicate that fainting, seizures, and abnormal EKG findings in should be taken more seriously.

“The more we understand the symptoms and EKG changes that may come before a sudden arrhythmic death, the better we can identify those at risk,” says Mats Börjesson, cardiologist and professor of sports physiology at the Sahlgrenska Academy, University of Gothenburg.

More information:
Matilda Frisk Torell et al, Sudden Arrhythmic Death Syndrome in the Young: Risk Factors are Identifiable Prior to Sudden Cardiac Arrest, The American Journal of Cardiology (2025). DOI: 10.1016/j.amjcard.2025.09.062


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