HMN 2025: What are the Odds of cardiovascular occasions up for RSV hospitalization versus COVID-19 hospitalization

Patients with respiratory syncytial virus (RSV) hospitalization have elevated odds of any acute cardiovascular occasion in contrast with COVID-19 hospitalizations, in response to a review printed on-line May 22 in JAMA Network Open.

Liang En Wee, M.P.H., from the National Centre for Infectious Diseases in Singapore, and colleagues in contrast the danger for acute cardiovascular problems in adults hospitalized for RSV versus COVID-19 or influenza in a cross-sectional study performed earlier than RSV vaccination rollout in Singapore. The study included 32,960 respiratory viral infections (RVIs; 2,148 for RSV; 14,389 for influenza; 16,423 for COVID-19).

Overall, 10.9 p.c of the two,148 sufferers hospitalized for RSV had an acute cardiovascular occasion. The researchers discovered that the percentages of any acute cardiovascular occasion have been larger in RSV hospitalizations versus boosted COVID-19 hospitalizations (not less than three vaccine doses; adjusted odds ratio, 1.31); the identical was seen for different particular person cardiac occasions (adjusted odds ratios, 1.52 and 1.75 for dysrhythmia and coronary heart failure, respectively). Patients hospitalized for RSV had larger odds of any acute cardiovascular occasion (adjusted odds ratio, 1.58) in addition to dysrhythmias or coronary heart failure in contrast with unboosted COVID-19 hospitalizations (not more than three vaccine doses). There was no vital distinction seen within the odds of a cardiovascular occasion in RSV versus influenza, other than contemporaneous hospitalizations after the pandemic (2023 to 2024), with considerably larger odds of coronary heart failure in RSV hospitalizations versus vaccine-breakthrough influenza hospitalizations (adjusted odds ratio, 2.09).

“Evaluating vaccination’s position in attenuating threat of cardiovascular occasions related to vaccine-preventable RVIs stays necessary given the supply of RSV vaccines for older adults,” the authors write. “Individuals with a preexisting cardiac historical past stay at larger threat of acute cardiac occasions throughout RSV hospitalization and needs to be prioritized for vaccination.”