Vaping is now more common than cigarette smoking among young people, according to a new report coordinated by the University of Glasgow and commissioned by the World Health Organization. This echoes research that has found the popularity of vaping among young people in the UK has surged in recent years. The number of children experimenting […]
U.S. recalls of foods for salmonella, foreign objects or undeclared allergens are rampant nowadays and the highest they’ve been since 2020, a watchdog group warns. “Everyone needs to do better: food producers, regulators and lawmakers,” said Teresa Murray, consumer watchdog at U.S. Public Interest Research Group (PIRG). “We shouldn’t have to worry that everything from […]
Until three years ago nobody had developed a vaccine against any parasitic disease. Now there are two against malaria: the RTS,S and the R21 vaccines. Adrian Hill, director of the Jenner Institute at the University of Oxford and chief investigator for the R21 vaccine, tells Nadine Dreyer why he thinks this is a great era […]
For patients with relapsed or refractory CD7-positive leukemia or lymphoma, sequential CD7 chimeric antigen receptor (CAR) T-cell therapy followed by haploidentical hematopoietic stem-cell transplantation (HSCT) is safe and effective, with remission seen for most patients, according to a study published in the New England Journal of Medicine. Yongxian Hu, M.D., Ph.D., from the Zhejiang University […]
This image shows the effect of protein-like polymers (red) in the brain cells of a mouse model. The nanoscale polymers are designed to alter the interaction between two proteins to combat oxidative stress in the cells. Credit: Johnson Lab/UW–Madison A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for […]
TRMT10C protein and mRNA levels are increased in AD cell and animal models and cortex samples of AD patients. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02421-y A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer’s patients resulting in a reduction of the supply of energy […]
The risk for postoperative respiratory complications is similar among patients undergoing emergency surgery regardless of preoperative glucagon-like peptide 1 receptor agonist (GLP-1 RA) use, according to a research letter published online April 22 in the Journal of the American Medical Association. Anjali A. Dixit, M.D., M.P.H., from Stanford University in California, and colleagues used a […]
Genome-wide CRISPR dropout screen identifies PRMT5 as an essential gene for survival of ER?+?/RB1-deficient breast cancer cells. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-46495-2 Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center […]
A nationwide survey of people who were pregnant or trying to become pregnant has found that overall, 54% expressed interest in the RSV vaccine during pregnancy. Perceiving RSV as a serious illness in infants was the strongest predictor of likely vaccination during pregnancy. Likelihood to receive the RSV vaccine during pregnancy was also higher among […]
Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related. For example, people with depression run a greater risk of CVD, while effective early treatment for depression […]
British pharmaceutical giant AstraZeneca on Thursday said net profit jumped 21 percent in the first three months of the year thanks to strong growth in sales of cancer drugs. Profit after tax climbed more than one fifth compared with the first quarter last year to $2.18 billion, AstraZeneca said in a results statement. “AstraZeneca had […]
The widespread use of alcohol and e-cigarettes among adolescents is “alarming”, according to a report released on Thursday by the World Health Organization’s (WHO) European branch, which recommended measures to limit access. Based on survey data from 280,000 young people aged 11, 13 and 15 in Europe, Central Asia and Canada, the WHO said it […]
Colorized transmission electron micrograph of Avian influenza A H5N1 viruses. Credit: Public Domain The discovery of traces of the bird flu virus in pasteurized cow milk in the United States sparked questions over whether the disease could spread to humans, but experts say there is little risk from food contamination. US authorities on Tuesday said […]
A pregnant woman stands for a portrait in Dallas, Thursday, May 18, 2023. According to provisional statistics for 2023 released by the Centers for Disease Control and Prevention on Thursday, April 25, 2024, U.S. births fell last year, in a substantial drop marking an apparent end to pandemic-related fluctuations and a return to a long-standing […]
Funmilayo Kotun, 66-years-old, a malaria patient is photographed in her one room in Makoko neighbourhood of Lagos, Nigeria, Saturday, April 20, 2024. When cases of locally transmitted malaria were found in the United States last year, it was a reminder that climate change is reviving the threat, or broadening the range, of some diseases. But […]
Funmilayo Kotun, 66-years-old, a malaria patient is photographed in her one room in Makoko neighbourhood of Lagos, Nigeria, Saturday, April 20, 2024. When cases of locally transmitted malaria were found in the United States last year, it was a reminder that climate change is reviving the threat, or broadening the range, of some diseases. But […]
A nurse administers an injection to a malaria patient in a ward at Nightingale Medical Centre, in Kisumu, Kenya Tuesday, April. 16, 2024. Even after parts of Kenya participated in an important pilot of the world’s first malaria vaccine, with a reported drop in deaths for children under 5, the disease is still a significant […]
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson’s disease. While decades of research have linked pesticide exposure and Parkinson’s disease risk, researchers have sought to explain why some individuals with high exposure develop the disease while others do not. […]
Genomic surveillance can help control infectious diseases and antimicrobial resistance. Credit: Struelens et al/Frontiers The COVID-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism. This powerful technology tracked the spread […]
Women with heart disease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024, a scientific congress of the European Society of Cardiology (ESC). “Cholesterol-lowering drugs save lives and prevent heart attacks, and should be prescribed to all patients with coronary artery disease,” said study author […]
Patients’ shadows are cast on a wall at a Doctors Without Borders medical clinic in Putucual, Venezuela, Wednesday, Jan. 10, 2024. A group of women and teenage girls visited the medical clinic in eastern Venezuela for free contraceptives where a community health worker taught them how to use an IUD, condoms and birth control pills […]
Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially causative variants for Mendelian disorders. The study is published in NEJM AI. […]
A collaboration between the University of Oxford and University of Leeds, it shows that the tests currently used by doctors can be unreliable. Using data on 27,000 babies, their research, published in JAMA, found the best tests miss over half of abnormal hips—and indicates that for every 1,000 hips screened, four dislocations will be identified, […]
A research team from the School of Nursing, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), found positive effects of tai chi and aerobic exercise on sleep quality, psychological well-being, physical function, and circadian rhythm in patients with advanced lung cancer. The study, conducted over a four-year period, discovered additional advantages in […]
Credit: National Institutes of Health In a landmark study, an international consortium led by researchers at Children’s Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs). […]
TM4SF19 mechanism regulating inflammatory response within adipose tissue. Credit: POSTECH A South Korean team has spearheaded a research endeavor that successfully uncovered the mechanisms governing inflammation and metabolic dysfunction in tissues associated with obesity. Their findings were published in Nature Communications. According to the World Health Organization (WHO), approximately 16% of the global population is […]
A case of active serpiginous choroiditis on color fundus photography (CFP), short-wavelength blue-light autofluorescence (swBAF, 450 nm), long-wavelength blue-light autofluorescence (lwBAF, 488 nm), green-light autofluorescence (GAF, 518 nm), and infrared-light autofluorescence (IRAF, 787 nm). Inactive lesions are completely hypoautofluorescent on FAF modalities, while active lesion borders depict a speckled pattern of hyper- and hypoautofluorescence. Credit: […]
Credit: Scientific Reports (2024). DOI:10.1038/s41598-024-52588-1 University of Waterloo researchers have invented a digital medical imaging system that significantly improves the cancer detection process to deliver immediate results and enable swift, effective treatment for all types of cancer. The Photon Absorption Remote Sensing (PARS) system, an innovative, built-from-scratch technology, is faster than traditional cancer-detection methods and […]
The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with non-Hispanic white individuals, mirroring changes in population growth rates. Survival after both autologous hematopoietic cell transplant (autoHCT) and allogeneic hematopoietic transplant (alloHCT) improved over time across racial/ethnic groups, though non-Hispanic African Americans still have […]
Credit: Markus Winkler from Pexels Semaglutide (sold as Ozempic, Wegovy and Rybelsus) was initially developed to treat diabetes. It works by stimulating the production of insulin to keep blood sugar levels in check. This type of drug is increasingly being prescribed for weight loss, despite the fact it was initially approved for another purpose. Recently, […]
Primary human hepatocytes display a circadian rhythm in culture. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9281 Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT. Using tiny, engineered livers derived from cells from human donors, the researchers found that many genes […]
There’s been an increase in content posted on TikTok and Instagram recently discussing the alleged dangers of birth control. Content creators have shared concerns about the pill’s side-effects ranging from weight gain to low libido and fluctuating moods. Other claims are misleading because they exaggerate the risks associated with contraception, cancer and infertility. Many of […]
Colorized SEM (scanning electron micrograph) of the foodborne pathogen Salmonella enteritidis. Blue is growth medium. Picture is colored in false colors to illustrate difference. Photo by Jean Guard, ARS. Credit: U.S. Department of Agriculture/public domain Climate change is multiplying the threat caused by antimicrobial resistance (AMR), amplifying its growing risk through increasing global temperatures, greenhouse […]
Fluorescence image of sensory axons, in red, connecting with visceral white fat tissue seven days after a spinal cord injury in an adult mouse. Credit: Andrea Tedeschi Conditions such as diabetes, heart attack, and vascular diseases commonly diagnosed in people with spinal cord injuries can be traced to abnormal post-injury neuronal activity that causes abdominal […]
In today’s digital age, social media platforms like TikTok have become integral parts of our lives, offering not just entertainment and catchy dances but also a wealth of information on topics ranging from home improvement to world news. According to some reports, many young people even prefer to use social media in place of traditional […]
Researchers from Aston University have found that people following healthy eating accounts on social media for as little as two weeks ate more fruit and vegetables and less junk food. The work is published in the journal DIGITAL HEALTH. Previous research has shown that positive social norms about fruit and vegetables increases individuals’ consumption. The […]
Anopheles gambiae mosquito, feeding on blood. Credit: James Gathany, Centers for Disease Control and Prevention The geographical range of vector-borne diseases, especially diseases such as malaria and dengue, that are transmitted by mosquitoes, has expanded rapidly over the last 80 years, with over half the world’s population now at risk. Spurred on by global warming […]
In terms of men’s health issues, prostate cancer features high on the agenda. It’s the second most diagnosed cancer in men globally—closely followed by lung cancer. And it’s the most common cancer in men in the UK. As the prostate is a reproductive organ with its main job being to help make semen—the fluid that […]
Each LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San Diego Researchers have created a thin film that combines an electrode grid and LEDs that can both track and produce a visual representation of the brain’s activity in real-time during surgery—a huge improvement over the current state […]
Survivors of childhood cancer are at increased risk for cardiovascular disease, for which a risk factor is their greater prevalence of type 2 diabetes, with a disproportionate impact on those of non-European heritage. St. Jude Children’s Research Hospital scientists have identified four previously unknown genetic variants associated with diabetes risk in all survivors. Published in […]
Schematic to show the direct (T1R3-dependent) and indirect (bacteria-dependent) impact of the artificial sweetener neotame on the intestinal epithelial cell. Credit: Frontiers in Nutrition (2024). DOI: 10.3389/fnut.2024.1366409 New research has discovered that neotame, one of the new generation of artificial sweeteners, is capable of damaging the human intestine and causing illness. The study is the […]
Experts are working on a new type of ultraviolet light called far-UVC that could be highly effective for reducing airborne transmission of diseases such as COVID-19 and influenza–as well as surface contamination in hospitals–with hopes that it could even reduce the risk of the next pandemic. In a new research review presented at this year’s […]
Dermatologists advise their patients to avoid harmful ultraviolet light, which can cause skin damage, photo-aging and skin cancer. But they also may prescribe light therapy to treat certain skin conditions. Light therapy is a treatment that uses different wavelengths of light to treat various skin conditions. In this Mayo Clinic Minute, Dr. Dawn Davis, a […]
As patients with congenital heart diseases live longer, researchers are attempting to understand some of the other complications they may face as they age. A team from Children’s Hospital of Philadelphia (CHOP) used state-of-the-art technologies to understand the underlying biology of Fontan-associated liver disease (FALD). The findings, published in Science Translational Medicine, reveal unprecedented insights […]
New research has found a significant association between participating in low to moderate intensity exercise and reduced rates of depression. Researchers from Anglia Ruskin University (ARU) carried out an umbrella review of studies carried out across the world to examine the potential of physical activity as a mental health intervention. The analysis, published in the […]
Nearly 40% of Americans live where the air is polluted enough to harm them, a new report warns. In the American Lung Association’s “State of the Air” report, released Wednesday, the number of people living with levels of air pollution that could jeopardize their health climbed from about 119 million in 2023 to 131 million […]
The U.S. Centers for Disease Control and Prevention has launched a new online heat forecaster to help communities better prepare for summer’s scorching temperatures. The HeatRisk Forecast Tool is a joint effort between the CDC and the National Oceanic and Atmospheric Administration National Weather Service to give Americans a week-long heads-up that broiling temperatures are […]
Credit: Karolina Grabowska from Pexels An Australian researcher says we should consider cholesterol screening earlier in life, with his team’s latest research showing that interventions to prevent and reduce “bad” cholesterol in childhood and young adulthood may help prevent premature heart disease later in life. Publishing in JAMA, researchers from the Baker Heart and Diabetes […]
A new study by investigators from Mass General Brigham demonstrates that large language models (LLMs), a type of generative AI, may help reduce physician workload and improve patient education when used to draft replies to patient messages. The study also found limitations to LLMs that may affect patient safety, suggesting that vigilant oversight of LLM-generated […]
Gene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Nodes are grouped by their module membership. Module genes that are enriched for at least one GO process are colored to represent their enrichment category. Node size reflects its number of connections. Credit: GEN Biotechnology (2024). DOI: […]
Mara Rue, Ph.D., co-lead author and scientist at the Allen Institute for Brain Science. Credit: Peter Kim/Allen Institute Scientists have long known that our brains are organized into specialized areas, each responsible for distinct tasks. The visual cortex processes what we see, for instance, while the motor cortex governs movement. But how these regions form—and […]
Evolution of annual per capita fish consumption over the past 50 years. A range of economic, nutritional, religious and ideological factors influence our diets. The key, however, lies in finding a balance that cares for both our health and that of the planet. The traditional Mediterranean and Atlantic diets are two options that meet these […]
U.S. health officials issued a warning Tuesday about counterfeit Botox injections that have sickened 22 people. Half of the individuals have ended up in the hospital, according to the Centers for Disease Control and Prevention. The agency issued an alert to doctors on Tuesday. The cases started in early November and have been reported in […]
Public health experts are calling for a ban on alcohol industry funded education programs in UK universities and schools, which they say normalize drinking and downplay the long term health risks of alcohol. They include an industry-backed “freshers’ week survival guide” for university students and a theater based educational program in schools funded by Diageo, […]
The majority of children and teens with chronic skin diseases such as acne, eczema, psoriasis, alopecia areata (hair loss) and vitiligo (pigment loss) feel stigmatized by peers for their condition and are sometimes bullied, reports a new Northwestern Medicine study. As a result, these children have a poor quality of life that includes suffering from […]
Credit: L. Francisco Lorenzo-Martín (EPFL) In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease. As our battle against cancer rages on, the quest for more sophisticated and realistic models […]
Proportion of persons with an improvement in HbA1c of 0.5% (5.5 mmol/mol) and 1% (11 mmol/mol) and time in range of 5% and 10%. Credit: Journal of Diabetes Science and Technology (2024). DOI: 10.1177/19322968241242386 Blood sugar levels improve when adults with type 1 diabetes use modern insulin pumps. These are the findings of a study […]
Opioid use during pregnancy is not associated with a substantial increase in the risk of neuropsychiatric disorders such as ADHD in children, finds a large study from South Korea published by The BMJ today. A slightly increased risk of neuropsychiatric disorders was found, but the researchers say this should not be considered clinically meaningful because […]
Survivors of breast cancer are at significantly higher risk of developing second cancers, including endometrial and ovarian cancer for women and prostate cancer for men, according to new research studying data from almost 600,000 patients in England. For the first time, the research has shown that this risk is higher in people living in areas […]
Schematic evolutionary simulation and tested optimization approaches. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2303165121 Cleveland Clinic researchers developed an artificial intelligence (AI) model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain […]
It can be difficult to understand how busy parents often feel lonely. But a new survey by The Ohio State University Wexner Medical Center finds it is a widespread issue that most parents experience. Credit: The Ohio State Wexner Medical Center A new national survey conducted by The Ohio State University Wexner Medical Center finds […]
If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet. A number of factors can influence whether and how they survive the trauma in the subsequent recovery phase. The administration of the anesthetic midazolam has a positive effect, as shown by a multicenter study […]
Overview of the study, highlighting the device fabrication, reprogramming of somatic cells into iPSCs, and neural induction of iPSCs using dual-SMAD inhibition protocol to yield neural stem cells. a) Process flow for fabrication of the microfluidic device with 0.4 and 0.6 mm high channels used for somatic cell reprogramming (R) and neural induction (N), respectively, […]
A university professor has found a way to help students—and himself—power through long lecture classes: exercise breaks. In a new study, a professor at The Ohio State University showed that five-minute exercise sessions during lectures were feasible and that students reported positive impacts on their attention and motivation, engagement with their peers and course enjoyment. […]
Dr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Hawkins/UNLV The world of Alzheimer’s treatments is at an inflection point as more potential drugs make their way out of clinical trials. On the heels of newly FDA-approved drugs Aduhelm (aducanumab) in 2021 and Leqembi (lecanemab) in 2023, a […]
Social isolation has been linked to faster cognitive decline and an increased risk of developing dementia, although the biological mechanisms of this association are not well understood. Now a new clinical trial by a team including investigators from Massachusetts General Hospital indicates that conversational interactions—a core component of human connections—can stimulate different brain functions among […]
Diagram showing history of sounds over time and asking whether sound 1 or 2 is louder? Credit: Sainsbury Wellcome Centre Neuroscientists have revealed that recency bias in working memory naturally leads to central tendency bias, the phenomenon where people’s (and animals’) judgements are biased towards the average of previous observations. Their findings may hint at […]
Schematic diagram of the study. (A) Schematic for the EEG analysis in this study. wPLI matrix and median frequency of alpha band were calculated from 31 channel EEG. FDA, one of the ES conditions, was obtained from wPLI network and median alpha frequency. (B) An example of synchronization characteristics of ES and non-ES network. The […]
A new study co-authored by a Yale economist provides evidence that insufficient antitrust enforcement in the U.S. hospital sector is contributing to reduced competition and higher prices for hospital care. The study, conducted in collaboration with researchers at Harvard, the University of Chicago, and the University of Wisconsin-Madison, found that of 1,164 mergers among the […]
A team of researchers from The University of Manchester has spent the last 18 months examining how faith spaces in Greater Manchester support different groups of older people within their communities. Greater Manchester has a growing older population which is becoming increasingly culturally diverse. The city region also faces high levels of inequality around health, […]
Self-administered acupressure (SAA) is an efficacious and cost-effective approach to relieve knee pain in middle-aged and older adults with probable knee osteoarthritis (OA), according to a study published online April 19 in JAMA Network Open. Wing-Fai Yeung, Ph.D., from the Hong Kong Polytechnic University, and colleagues evaluated the effectiveness of SAA taught via a short […]
Immigrants to Canada who have spent a greater proportion of their lives in Canada have a greater risk of developing multiple sclerosis (MS) than people who have spent a smaller proportion of their lives there, according to a study published in the April 24, 2024, online issue of Neurology. The study does not prove that […]
People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, […]
Flow chart of the study design. Credit: Aging (2024). DOI: 10.18632/aging.205711 A new research paper titled “Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study” has been published in Aging. The COVID-19 pandemic poses a heavy burden on public health and accounts for substantial mortality […]
The World Health Organization (WHO) called Wednesday for a strengthening of global detection networks for the H5N1 bird flu virus which infected a large number of animal species. Earlier this month, the H5N1 virus was detected in very high concentrations in raw, or unpasteurised, milk from infected cows—a surprising development for experts because they were […]
Personal mask-wearing rates (from February to October 2023). Credit: 2024 Asako Miura Historically, we have tried to learn from our responses to large-scale health emergencies to prevent future health crises, but the factors influencing public health behavior are deeply complex. In a study recently published in Japanese Psychological Research, researchers from Osaka University examined how […]
Recent studies have shown that an abnormally high expression of MALAT1 in blood cancer cells could aid the chemotherapeutic resistance development through multiple intermolecular interactions. Although researchers first identified the role of MALAT1 in patients with non-small-cell lung cancer, it has recently garnered interest in blood cancer owing to a large body of evidence implicating […]
Credit: Tara Winstead from Pexels Around 1 in 20 people has attention-deficit hyperactivity disorder (ADHD). It’s one of the most common neurodevelopmental disorders in childhood and often continues into adulthood. ADHD is diagnosed when people experience problems with inattention and/or hyperactivity and impulsivity that negatively impacts them at school or work, in social settings and […]
Graphical abstract summarizes the workflow and major findings of the study. Credit: Science China Press In a recent study published in the Science Bulletin, researchers comprehensively examined the composition and phenotypic features of myeloid cells in human failing hearts at a single-cell level, offering valuable insights into potential targets for monitoring and treating cardiac inflammation […]
The suicide rate for men is about four times higher than for women. While men make up 50% of the population, they account for 80% of the suicides. Yet, suicide risk in men often goes unnoticed. Now new research may offer hope. A UCLA-led study of public health records has identified a vocabulary associated with […]
EPOC X Electrode Montage (adapted from Williams et al., 2023). Credit: Frontiers in Neuroergonomics (2024). DOI: 10.3389/fnrgo.2024.1340732 As people age, their brains do, too. But if a brain ages prematurely, there is potential for age-related diseases such as mild cognitive impairment, dementia, or Parkinson’s disease. If “brain age” could be easily calculated, then premature brain […]
Left anterior descending coronary artery with atherosclerotic lesion immunofluorescently stained for alpha-smooth muscle cell (green), collagen-I (red) and nuclei (blue) in an animal model. Credit: Dr. Onorina Manzo Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting […]
This study analyzed 1,937 infertile and 640 fertile men, validating disease-causing variants in RASopathy-linked genes. Credit: Andero Kalju. A surprisingly high fraction of infertile men presenting congenital testicular maldescent, cryptorchidism were revealed as undiagnosed cases of congenital RASopathy syndromes, as stated in a recent publication in Frontiers in Endocrinology by researchers from the University of […]
For years, even as opioid overdose deaths dramatically increased, doctors and other prescribers in the United States needed special permission from the federal government if they wanted to prescribe buprenorphine, a medication that helps patients overcome opioid addiction and prevents fatal overdoses. That requirement, called an “X waiver,” was eliminated on January 12, 2023, due […]
To make chemotherapy dosing more accurate, MIT engineers have come up with a way to continuously measure how much drug is in the patient’s system during the hours-long infusion. This could help compensate for differences caused by body composition, genetics, drug toxicity, and circadian fluctuations. Credit: Courtesy of the researchers When cancer patients undergo chemotherapy, […]
NECTIN4 amplification predicts EV response in mUC. Credit: Journal of Clinical Oncology (2024). DOI: 10.1200/JCO.23.01983 An interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin. The study, published in the Journal of Clinical Oncology, […]
There are many factors which affect how successfully a vaccine is rolled out. One of these is the public health communication strategy. Surprisingly, a key factor in determining the success of these strategies is religion. While some religious groups were keen to be vaccinated against COVID-19, others were much more hesitant. During the height of […]
In a proof-of-concept study, researchers demonstrated the effectiveness of a potential new therapy for Timothy syndrome, an often life-threatening and rare genetic disorder that affects a wide range of bodily systems, leading to severe cardiac, neurological, and psychiatric symptoms as well as physical differences such as webbed fingers and toes. The treatment restored typical cellular […]
Credit: Tima Miroshnichenko from Pexels The Professional Women’s Hockey League (PWHL) has gained immense popularity since its inception in 2023. It has boasted a number of sold out games and has set audience attendance records in Toronto, Ottawa, Montréal, Detroit and Minnesota. Despite this, the league is still lacking in safety measures. Currently, the PWHL […]
Pathological assessments of brains from individuals with Pick’s disease. Credit: The Lancet Neurology (2024). DOI: 10.1016/S1474-4422(24)00083-8 Pick’s disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65. The condition causes changes in personality, behavior and sometimes language impairment. In patients with the […]
Overall procedure of wheeze counting algorithm development and applications. Credit: PLOS ONE (2023). DOI: 10.1371/journal.pone.0294447 A University of Texas at Dallas researcher and his international colleagues have developed an algorithm that might one day provide early medical alerts about the onset of asthma attacks or other respiratory problems. The algorithm, described in a study published […]
The unique circumstances arising from the COVID-19 pandemic altered a long-held convention that doctors provide care regardless of personal risk. In a study assessing doctors’ tolerance for refusing care to COVID-19 patients, Duke Health researchers identified a growing acceptance to withhold care because of safety concerns. “All the papers throughout history have shown that physicians […]
Graphical abstract. Credit: iScience (2024). DOI: 10.1016/j.isci.2024.109288 A new paper describes the role of two RNA-binding proteins in the development of sarcoma and carcinoma cancers, highlighting the important and emerging role of RNA-binding proteins in cancer research and offering a new avenue for therapeutic targets. This research was a key component of the Ph.D. thesis […]
A team of MIT researchers found highly memorable images have stronger and sustained responses in ventro-occipital brain cortices, peaking at around 300ms. Conceptually similar but easily forgettable images quickly fade away. Credit: Alex Shipps/MIT CSAIL For nearly a decade, a team of MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers have been seeking to […]
Cedars-Sinai investigators can identify comprehensive cardiovascular risk from CT scans obtained without contrast dye, which some patients cannot tolerate, through the use of AI algorithms. Credit: Cedars-Sinai Medical Center A recent study designed and implemented by investigators at Cedars-Sinai found that artificial intelligence (AI) can accurately evaluate cardiovascular risk during a routine chest computed tomography […]
An artistic recreation of MRSA. Michigan State University researcher Xuefei Huang is developing new vaccine science in the fight against antibiotic resistance. Credit: Jennifer Oosthuizen, medical illustrator. Centers for Disease Control and Prevention Public Health Image Library. Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments. It’s estimated that […]
The majority of children and teens with chronic skin diseases such as acne, eczema, psoriasis, alopecia areata (hair loss) and vitiligo (pigment loss) feel stigmatized by peers for their condition and are sometimes bullied, reports a new Northwestern Medicine study. As a result, these children have a poor quality of life that includes suffering from […]
A new study published in JAMA led by John W. Ayers, Ph.D., from the Qualcomm Institute within UC San Diego, finds that X’s Community Notes, a crowdsourced approach to addressing misinformation, countered false health information in popular posts about COVID-19 vaccines with accurate, credible responses. Credit: Screenshot by Qualcomm Institute, UC San Diego As the […]
Nursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understaffed, according to a study published in JAMA Network Open. “The neighborhood in which a nursing home is located seems to influence how widely antipsychotics are used, even when they may not be indicated,” said Jasmine Travers, assistant […]
Multimodal analyses of cells from abnormal tunnels in Crohn’s disease converge to illuminate underlying pathomechanisms. Credit: Med/Cell Press (Elsevier) Mount Sinai researchers have published the first study to use single-cell analysis in identifying several pathophysiological mechanisms of abnormal passageways in the digestive system known as perianal fistulae, a common complication of Crohn’s disease. These findings […]