{"id":44329,"date":"2016-07-20T15:00:53","date_gmt":"2016-07-20T15:00:53","guid":{"rendered":"http:\/\/healthmedicinet.com\/news\/cant-stop-scratching-breakthrough-makes-drug-to-stop-all-types-of-itch-from-skin-conditions-to-insect-bites\/"},"modified":"2016-07-20T15:00:53","modified_gmt":"2016-07-20T15:00:53","slug":"cant-stop-scratching-breakthrough-makes-drug-to-stop-all-types-of-itch-from-skin-conditions-to-insect-bites","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/news\/cant-stop-scratching-breakthrough-makes-drug-to-stop-all-types-of-itch-from-skin-conditions-to-insect-bites\/","title":{"rendered":"Can\u2019t stop scratching? Breakthrough makes drug to stop ALL types of itch \u2013 from skin conditions to insect bites"},"content":{"rendered":"<ul class=\"mol-bullets-with-font\">\n<li class=\"\"><strong>Scientists find protein that tells brain something has irritated our skin<\/strong><\/li>\n<li class=\"\"><strong>And, in turn, it is time to start scratching to try and ease the irritation<\/strong><\/li>\n<li class=\"\"><strong>Protein is called TRPV4. It is involved in processing the type of itch produced by insect bites and that provoked by allergy to a medicine<\/strong><\/li>\n<\/ul>\n<p class=\"author-section byline-plain\">By<\/p>\n<p>Fiona Macrae Science Editor For The Daily Mail<\/p>\n<p class=\"byline-section\"><span class=\"article-timestamp article-timestamp-published\"><br \/><span class=\"article-timestamp-label\">Published:<\/span><br \/>\n  08:36 EST, 20 July 2016<br \/><\/span><br \/>\n | <span class=\"article-timestamp article-timestamp-updated\"><br \/><span class=\"article-timestamp-label\">Updated:<\/span><br \/>\n  08:36 EST, 20 July 2016<br \/><\/span>\n<\/p>\n<ul>\n<li class=\"share-facebook\"><\/li>\n<li class=\"share-twitter\"><\/li>\n<li class=\"share-pinterest\"><\/li>\n<li class=\"share-gplus\">\n      <span class=\"g-interactivepost\"><br \/><a><\/a><br \/><\/span>\n    <\/li>\n<li class=\"share-email\">\n<\/li>\n<\/ul>\n<p> <span><\/span><\/p>\n<p class=\"count-number\">           1<\/p>\n<p class=\"count-text\">View <br \/> comments<\/p>\n<\/p>\n<p class=\"mol-para-with-font\">\n<p>      <img loading=\"lazy\" decoding=\"async\" id=\"i-8375689108b6737e\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/20\/14\/3671370100000578-3699396-Scientists_have_identified_a_protein_that_tells_the_brain_someth-a-7_1469021367414.jpg\" height=\"330\" width=\"306\" alt=\"Scientists have identified a protein that tells the brain something has irritated our skin and it is time to start scratching\" class=\"blkBorder img-share\" \/><\/p>\n<p class=\"imageCaption\">Scientists have identified a protein that tells the brain something has irritated our skin and it is time to start scratching<\/p>\n<p class=\"mol-para-with-font\">Scientists may have put their finger on how to stop an itch.<\/p>\n<p class=\"mol-para-with-font\">They have identified a protein that tells the brain something has irritated our skin and it is time to start scratching.<\/p>\n<p class=\"mol-para-with-font\">Excitingly, the compound may be key to multiple types of itch \u2013 meaning a drug that stops it from working could make life more pleasant for millions.<\/p>\n<p class=\"mol-para-with-font\">While insect bites and washing powder allergies can be maddening while they last, itching is also part and parcel of illnesses from eczema to diabetes and kidney disease.<\/p>\n<p class=\"mol-para-with-font\">And some cancer patients find their painkillers irritate their skin so much that they have no option but to cut back on them.<\/p>\n<p class=\"mol-para-with-font\">The breakthrough, from Washington University, Missouri, centres on a cluster of cells that help transmit itch signals from the skin to the brain.<\/p>\n<p class=\"mol-para-with-font\">The researchers identified a protein in the cells which is called TRPV4 and is involved in processing the type of itch produced by insect bites and the type of itch provoked by an allergy to a medicine.<\/p>\n<p class=\"mol-para-with-font\">This is important because it had been thought that different types of itch were processed separately and so required different types of drug.<\/p>\n<p class=\"mol-para-with-font\">The researchers think the protein might also be involved in other types of itch \u2013 meaning a drug that stops it from working could help everyone from holidaymakers peppered with mosquito bites to cancer patients.<\/p>\n<p class=\"mol-para-with-font\">Writing in the journal Science Signalling, researcher Zhou-Feng Chen said: \u2018It gives us new therapeutic targets.<\/p>\n<p class=\"mol-para-with-font\">\u2018We may be able to inhibit multiple types of itching.\u2019<\/p>\n<ul class=\"rotator-panels link-bogr1 linkro-ccox\">\n<li>\n<p>          <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/20\/09\/366FA5C400000578-0-image-a-10_1469003644920.jpg\" alt=\"\" width=\"62\" height=\"60\" \/><span>Are YOU fed up with sweating? Well it\u2019s actually the reason\u2026<\/span><\/p>\n<p>          <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/19\/20\/366C003F00000578-0-image-a-12_1468955947699.jpg\" alt=\"\" width=\"62\" height=\"60\" \/><span>Desperate to lose weight? Cut calories by ordering your food\u2026<\/span><\/p>\n<p>          <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/19\/08\/3667AB2000000578-0-image-a-6_1468911998425.jpg\" alt=\"\" width=\"62\" height=\"60\" \/><span>The girl who sneezes 8,000 times a day \u2013 but doctors have no\u2026<\/span><\/p>\n<p>          <img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/20\/10\/36701C1E00000578-0-image-a-9_1469007621539.jpg\" alt=\"\" width=\"62\" height=\"60\" \/><span>How much marijuana IS there in the average joint? Less than\u2026<\/span><\/p>\n<\/li>\n<\/ul>\n<p>      <img loading=\"lazy\" decoding=\"async\" id=\"i-741d8e41efa8b0e8\" src=\"http:\/\/i.dailymail.co.uk\/i\/pix\/2016\/07\/20\/14\/3671391C00000578-3699396-image-m-5_1469021202729.jpg\" height=\"613\" width=\"634\" alt=\"While insect bites and washing powder allergies can be maddening while they last, itching is also part and parcel of illnesses from eczema to diabetes and kidney disease\" class=\"blkBorder img-share\" \/><\/p>\n<p class=\"imageCaption\">While insect bites and washing powder allergies can be maddening while they last, itching is also part and parcel of illnesses from eczema to diabetes and kidney disease<\/p>\n<p class=\"mol-para-with-font\">Dr Chen, who rather appropriately runs his university\u2019s Centre for the Study of the Itch, has previously proved that mother was right when she said that scratching makes an itch worse.<\/p>\n<p class=\"mol-para-with-font\">He showed that while scratching provides temporary relief, it quickly triggers the production of a brain chemical that makes the itch even more annoying.<\/p>\n<p class=\"mol-para-with-font\">It appears that scratching initially helps by creating pain.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Nerve cells in the spinal cord are kept busy transmitting pain signals to the brain, leaving fewer to tell the brain about the itch.<\/p>\n<p class=\"mol-para-with-font\">But when the brain registers the soreness caused by our fingernails scraping across our skin, it releases the chemical serotonin.<\/p>\n<p class=\"mol-para-with-font\">This is meant to dull the pain but also intensifies the itch, leading to a vicious circle of more scratching, more serotonin being released \u2013 and more itching.\u00a0<\/p>\n<p class=\"mol-para-with-font\">\n<h3 class=\"social-links-title\">Share or comment on this article<\/h3>\n<ul class=\"bigLinks sc-icns cleared\">\n<li class=\"facebook\">\n<\/li>\n<li id=\"addCommentButton\" 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Sickening video shows\u2026<\/span><\/p>\n<\/li>\n<\/ul>\n<p>                                <img decoding=\"async\" src=\"http:\/\/f.dailymail.co.uk\/i\/furniture\/comments\/articles\/btn_add-your-comment.png\" \/><\/p>\n<p>                            <img decoding=\"async\" src=\"http:\/\/f.dailymail.co.uk\/i\/furniture\/comments\/articles\/icon_comments_74.png\" \/><\/p>\n<h3>Comments (<span class=\"readerCommentsCount\">1<\/span>)<\/h3>\n<p>\n                                \tShare what you think\n                                <\/p>\n<ul id=\"rc-tabs\" class=\"js-links dm-tabs cnr5 cleared\">\n<li class=\"dm-tab dm-tab-on bdrgr5 cnr-bdr wogr5 link-wox js-active\">\n                            <span class=\"xogr5 tl\"><\/span><br \/><span class=\"xogr5 tr\"><\/span><br \/>\n                            Newest\n                        <\/li>\n<li class=\"dm-tab bdrgr5 ow-igr2-bx cnr-bdr xogr2 link-gr5ox\">\n                            <span class=\"xogr5 tl\"><\/span><br \/><span class=\"xogr5 tr\"><\/span><br \/>\n                            Oldest\n                        <\/li>\n<li class=\"dm-tab bdrgr5 ow-igr2-bx cnr-bdr xogr2 link-gr5ox\">\n                            <span class=\"xogr5 tl\"><\/span><br \/><span class=\"xogr5 tr\"><\/span><br \/>\n                            Best rated\n                        <\/li>\n<li class=\"dm-tab bdrgr5 ow-igr2-bx cnr-bdr xogr2 link-gr5ox last\">\n                            <span class=\"xogr5 tl\"><\/span><br \/><span class=\"xogr5 tr\"><\/span><br \/>\n                            Worst rated\n                        <\/li>\n<\/ul>\n<p>The comments below have not been moderated.<\/p>\n<p class=\"bold pad5 wogr5 rc-info\">\n                        The views expressed in the contents above are those of our users and do not necessarily reflect the views of MailOnline.\n                    <\/p>\n<\/p>\n<p>                    Find out now<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists find protein that tells brain something has irritated our skin And, in turn, it is time to start scratching to try and ease the irritation Protein is called TRPV4. It is involved in processing the type of itch produced by insect bites and that provoked by allergy to a medicine By Fiona Macrae Science [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-44329","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts\/44329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/comments?post=44329"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/posts\/44329\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/media?parent=44329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/categories?post=44329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/news\/wp-json\/wp\/v2\/tags?post=44329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}