
In a synopsis of a clinical practice guideline issued by the U.S. Department of Veterans Affairs and U.S. Department of Defense and published online Feb. 17 in the Annals of Internal Medicine, updated recommendations are presented for the primary care management of asthma in veterans and military members.
Amir Sharafkhaneh, M.D., Ph.D., from the Michael E. DeBakey VA Medical Center in Houston, and colleagues present updated recommendations regarding evaluation and management of veterans and military members with asthma. Twelve key questions were developed, and 21 evidence-based recommendations were advanced following evaluation of the evidence.
The authors note that inhaled corticosteroids are strongly recommended; management of asthma is streamlined with recommendations of a combination of inhaled corticosteroids and rapid-onset long-acting ?-agonists as both reliever and controller agents, as well as step-up therapy by increasing inhaled corticosteroids and/or the addition of long-acting anticholinergic agents. Management of symptomatic gastroesophageal reflux disease and obesity are also supported for better control of asthma. Use of indoor air filtration devices is not suggested. Decision points are outlined for referral to a subspecialist.
“Asthma management within primary care is pivotal for enhancing patient outcomes and reducing health care burdens,” the authors write.
Publication details
Amir Sharafkhaneh et al, A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for the Primary Care Management of Asthma, Annals of Internal Medicine (2026). DOI: 10.7326/annals-25-03080
James G. Krings, A New Approach to Reliever Therapy in Asthma: Implications of the U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline, Annals of Internal Medicine (2026). DOI: 10.7326/annals-25-05637
Journal information:
Annals of Internal Medicine
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