Study discovers connection between between heart and brain in KBG syndrome

Ankrd11 is expressed in cardiac neural crest cells and ablated in the Ankrd11ncko mouse model. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-48955-1 A new study sheds light on a medical question scientists have long wondered: why do 40% of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain. The research is published in the journal Nature Communications. KBG syndrome can cause unusual facial development, skeletal abnormalities, intellectual underdevelopment and heart defects. The syndrome is caused Read More

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