{"id":1568,"date":"2024-06-14T16:06:47","date_gmt":"2024-06-14T16:06:47","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/study-reveals-fus-proteins-role-in-two-neurodegenerative-diseases\/"},"modified":"2024-06-14T16:06:47","modified_gmt":"2024-06-14T16:06:47","slug":"study-reveals-fus-proteins-role-in-two-neurodegenerative-diseases","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/study-reveals-fus-proteins-role-in-two-neurodegenerative-diseases\/","title":{"rendered":"Study reveals FUS protein\u2019s role in two neurodegenerative diseases"},"content":{"rendered":"<p>HA-FUSR495X fibrils induce human FUS mislocalization and aggregation in aged humanized mutantFUS (mFUSKO\/hFUSR521H) mice. Credit: Molecular Neurodegeneration (2024). DOI: 10.1186\/s13024-024-00737-5 Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role, but the exact mechanism remained a mystery. A new study by the lab of Prof. Sandrine Da Cruz published in Molecular Neurodegeneration reveals how the FUS protein behaves in these diseases, which is crucial for potential therapeutic interventions. Frontotemporal dementia (FTD) is a form of <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/study-reveals-fus-proteins-role-in-two-neurodegenerative-diseases\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>HA-FUSR495X fibrils induce human FUS mislocalization and aggregation in aged humanized mutantFUS (mFUSKO\/hFUSR521H) mice. Credit: Molecular Neurodegeneration (2024). DOI: 10.1186\/s13024-024-00737-5 Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role, but the exact mechanism remained a mystery. A new study [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1568","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/1568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=1568"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/1568\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=1568"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=1568"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=1568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}