{"id":1693,"date":"2024-06-17T17:03:18","date_gmt":"2024-06-17T17:03:18","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/mouse-study-suggests-cancer-drug-could-be-used-to-target-protein-connection-that-spurs-parkinsons-disease\/"},"modified":"2024-06-17T17:03:18","modified_gmt":"2024-06-17T17:03:18","slug":"mouse-study-suggests-cancer-drug-could-be-used-to-target-protein-connection-that-spurs-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/mouse-study-suggests-cancer-drug-could-be-used-to-target-protein-connection-that-spurs-parkinsons-disease\/","title":{"rendered":"Mouse study suggests cancer drug could be used to target protein connection that spurs Parkinson\u2019s disease"},"content":{"rendered":"<p>Neurons express Aplp1 (in white), a key protein that allows brain cells to absorb Parkinson&#8217;s-disease causing alpha-synuclein. Credit: Yasuyoshi Kimura, Ph.D. In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson&#8217;s disease-causing alpha-synuclein. The findings, published May 31 in Nature Communications, reveal how Aplp1 connects with Lag3, another cell surface receptor, in a key part of a process that helps spread harmful alpha-synuclein proteins to brain cells. Those protein <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/mouse-study-suggests-cancer-drug-could-be-used-to-target-protein-connection-that-spurs-parkinsons-disease\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neurons express Aplp1 (in white), a key protein that allows brain cells to absorb Parkinson&#8217;s-disease causing alpha-synuclein. Credit: Yasuyoshi Kimura, Ph.D. In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson&#8217;s disease-causing alpha-synuclein. The [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1693","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/1693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=1693"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/1693\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=1693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=1693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=1693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}