{"id":2918,"date":"2024-07-08T17:55:15","date_gmt":"2024-07-08T17:55:15","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/researchers-identify-molecule-as-potential-treatment-for-angelman-syndrome\/"},"modified":"2024-07-08T17:55:15","modified_gmt":"2024-07-08T17:55:15","slug":"researchers-identify-molecule-as-potential-treatment-for-angelman-syndrome","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/researchers-identify-molecule-as-potential-treatment-for-angelman-syndrome\/","title":{"rendered":"Researchers identify molecule as potential treatment for Angelman syndrome"},"content":{"rendered":"<p>Neurons with a fluorescent reporter for paternal UBE3A gene activity show only a background low fluorescent glow when treated with a vehicle control, but show a bright fluorescent glow when treated with (S)-PHA533533, indicating that the small molecule potently activated the dormant paternal allele of UBE3A. Credit: Vihma et. al 2024 Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities. Though there isn&#8217;t a cure for the condition, new research at the <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/researchers-identify-molecule-as-potential-treatment-for-angelman-syndrome\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neurons with a fluorescent reporter for paternal UBE3A gene activity show only a background low fluorescent glow when treated with a vehicle control, but show a bright fluorescent glow when treated with (S)-PHA533533, indicating that the small molecule potently activated the dormant paternal allele of UBE3A. Credit: Vihma et. al 2024 Angelman syndrome is a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2918","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/2918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=2918"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/2918\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=2918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=2918"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=2918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}