{"id":2919,"date":"2024-07-08T17:48:07","date_gmt":"2024-07-08T17:48:07","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/scientists-create-first-mouse-model-with-complete-functional-human-immune-system\/"},"modified":"2024-07-08T17:48:07","modified_gmt":"2024-07-08T17:48:07","slug":"scientists-create-first-mouse-model-with-complete-functional-human-immune-system","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/scientists-create-first-mouse-model-with-complete-functional-human-immune-system\/","title":{"rendered":"Scientists create first mouse model with complete, functional human immune system"},"content":{"rendered":"<p>Left, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale bar, 20??m) and kidney immunopathology (H&#038;E and anti-huIgG immunofluorescence; scale bar, 100??m) in Lupus THX and THX mice (12 weeks after pristane or PBS injection). Credit: Nature Immunology (2024). DOI: 10.1038\/s41590-024-01880-3 A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created a humanized mouse model with a human immune system and a human-like <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/scientists-create-first-mouse-model-with-complete-functional-human-immune-system\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Left, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale bar, 20??m) and kidney immunopathology (H&#038;E and anti-huIgG immunofluorescence; scale bar, 100??m) in Lupus THX and THX mice (12 weeks after pristane or PBS injection). Credit: Nature Immunology (2024). DOI: 10.1038\/s41590-024-01880-3 A breakthrough for biomedical research [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2919","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/2919","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=2919"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/2919\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=2919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=2919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=2919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}