{"id":3576,"date":"2024-07-11T18:33:54","date_gmt":"2024-07-11T18:33:54","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/nasal-spray-found-to-clear-tau-proteins-from-alzheimers-mouse-model-brains\/"},"modified":"2024-07-11T18:33:54","modified_gmt":"2024-07-11T18:33:54","slug":"nasal-spray-found-to-clear-tau-proteins-from-alzheimers-mouse-model-brains","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/nasal-spray-found-to-clear-tau-proteins-from-alzheimers-mouse-model-brains\/","title":{"rendered":"Nasal spray found to clear tau proteins from Alzheimer\u2019s mouse model brains"},"content":{"rendered":"<p>Immunostaining images showing differential PK sensitivity of tau aggregates in brain homogenates from IgG-ms- and TTCM2-ms\u2013treated mice. Credit: Science Translational Medicine (2024). DOI: 10.1126\/scitranslmed.adj5958 A multi-institutional team of neuroscientists has developed a nasal therapy that cleared the brains of Alzheimer&#8217;s mouse models of toxic tau proteins. In their study, published in the journal Science Translational Medicine, the group found a certain conformation-specific antibody that would bind to tau proteins, placed it inside of a shell that allowed it to travel through the blood brain barrier, and then tested it with <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/nasal-spray-found-to-clear-tau-proteins-from-alzheimers-mouse-model-brains\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Immunostaining images showing differential PK sensitivity of tau aggregates in brain homogenates from IgG-ms- and TTCM2-ms\u2013treated mice. Credit: Science Translational Medicine (2024). DOI: 10.1126\/scitranslmed.adj5958 A multi-institutional team of neuroscientists has developed a nasal therapy that cleared the brains of Alzheimer&#8217;s mouse models of toxic tau proteins. In their study, published in the journal Science Translational [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3576","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3576","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=3576"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3576\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=3576"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=3576"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=3576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}