{"id":3636,"date":"2024-07-12T15:28:04","date_gmt":"2024-07-12T15:28:04","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/new-discovery-suggests-opportunity-to-improve-effectiveness-of-kras-inhibitors-against-pancreatic-cancer\/"},"modified":"2024-07-12T15:28:04","modified_gmt":"2024-07-12T15:28:04","slug":"new-discovery-suggests-opportunity-to-improve-effectiveness-of-kras-inhibitors-against-pancreatic-cancer","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/new-discovery-suggests-opportunity-to-improve-effectiveness-of-kras-inhibitors-against-pancreatic-cancer\/","title":{"rendered":"New discovery suggests opportunity to improve effectiveness of KRAS inhibitors against pancreatic cancer"},"content":{"rendered":"<p>Pancreas cancer harbors cells in different states, with classical cells (red) and basal cells (turquoise) co-existing within individual tumors. Basal cells, which typically are associated with aggressive disease, show increased sensitivity to KRAS inhibitors, a promising new drug class for pancreatic cancer. Credit: Memorial Sloan Kettering Cancer Center Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment. Now, researchers at Memorial Sloan <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/new-discovery-suggests-opportunity-to-improve-effectiveness-of-kras-inhibitors-against-pancreatic-cancer\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pancreas cancer harbors cells in different states, with classical cells (red) and basal cells (turquoise) co-existing within individual tumors. Basal cells, which typically are associated with aggressive disease, show increased sensitivity to KRAS inhibitors, a promising new drug class for pancreatic cancer. Credit: Memorial Sloan Kettering Cancer Center Mutations in the KRAS gene are the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3636","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=3636"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3636\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=3636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=3636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=3636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}