{"id":3640,"date":"2024-07-12T15:17:54","date_gmt":"2024-07-12T15:17:54","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/researchers-pave-way-to-target-an-autoimmune-disease-associated-gene-variant\/"},"modified":"2024-07-12T15:17:54","modified_gmt":"2024-07-12T15:17:54","slug":"researchers-pave-way-to-target-an-autoimmune-disease-associated-gene-variant","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/researchers-pave-way-to-target-an-autoimmune-disease-associated-gene-variant\/","title":{"rendered":"Researchers pave way to target an autoimmune disease-associated gene variant"},"content":{"rendered":"<p>Superimposed structures of the SRA domain bound to DNA double helix (orange) from the 3CLZ.pdb, modeled CMFT bound SRA (yellow) and methylated cytosine (green). Credit: Journal of Biological Chemistry (2024). DOI: 10.1016\/j.jbc.2024.107443 In a new study, Yale researchers identified a molecule that binds to a disease-associated macrophage migration inhibitory factor (MIF) gene variant. The discovery, they say, could lead to the development of a new generation of precision medicine-based therapies that address diverse autoimmune and inflammatory conditions. The findings were published in the Journal of Biological Chemistry. Many autoimmune and <a class=\"read-more-link\" href=\"https:\/\/healthmedicinet.com\/researchers-pave-way-to-target-an-autoimmune-disease-associated-gene-variant\/\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Superimposed structures of the SRA domain bound to DNA double helix (orange) from the 3CLZ.pdb, modeled CMFT bound SRA (yellow) and methylated cytosine (green). Credit: Journal of Biological Chemistry (2024). DOI: 10.1016\/j.jbc.2024.107443 In a new study, Yale researchers identified a molecule that binds to a disease-associated macrophage migration inhibitory factor (MIF) gene variant. The discovery, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3640","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=3640"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/3640\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=3640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=3640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=3640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}