{"id":5276,"date":"2024-10-30T20:31:30","date_gmt":"2024-12-10T03:46:29","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/?p=5276"},"modified":"2024-12-10T03:46:29","modified_gmt":"2024-12-10T03:46:29","slug":"hmn-phendimetrazine-vs-phentermine-differences-similarities-and-which-is-better-for-you-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-phendimetrazine-vs-phentermine-differences-similarities-and-which-is-better-for-you-in-2025\/","title":{"rendered":"HMN: Phendimetrazine vs. phentermine: Differences, similarities, and which is better for you in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Phendimetrazine vs. phentermine: Differences, similarities, and which is better for you in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p>Phendimetrazine and phentermine are prescription weight-loss medications that work as appetite suppressants and are used to treat obesity, but they differ in dosage forms, age restrictions, and controlled substance classifications.<\/p>\n<\/li>\n<li>\n<p>Both medications are recommended for short-term use in conjunction with a reduced-calorie diet and exercise program, and their effectiveness tends to decrease over time.<\/p>\n<\/li>\n<li>\n<p>Common side effects include high blood pressure, palpitations, and insomnia, and they share similar drug interactions and contraindications, including risks when combined with MAOIs or alcohol.<\/p>\n<\/li>\n<li>\n<p>They are not typically covered by insurance or Medicare, and costs can vary, but discount programs like  may help lower the expense.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p><a href=\"#main-differences\">Main differences<\/a> | <a href=\"#conditions-treated\">Conditions treated<\/a> | <a href=\"#efficacy\">Efficacy<\/a> | <a href=\"#coverage-and-cost-comparison\">Coverage and cost comparison<\/a> | <a href=\"#side-effects\">Side effects<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#faqs\">FAQs<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are prescription weight-loss medications that work in similar ways. They are generally prescribed to individuals <\/span><span style=\"font-weight: 400;\">who are obese<\/span><span style=\"font-weight: 400;\"> or overweight with certain risk factors, such as high blood pressure, diabetes, or high cholesterol.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both phendimetrazine and phentermine are generic medications that are only available with a prescription. They are mainly classified as anorectics or appetite suppressants, sympathomimetic amines, and <\/span><span style=\"font-weight: 400;\">stimulants<\/span><span style=\"font-weight: 400;\">. Both phendimetrazine and phentermine are only recommended for a short duration with an appropriate diet and exercise plan. Because they are chemically similar to amphetamines, phendimetrazine and phentermine are controlled substances that carry a risk of abuse.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Continue reading to learn about the similarities and differences between phendimetrazine and phentermine, including their effectiveness, safety, and costs.<\/span><\/p>\n<h2 id=\"main-differences\"><span style=\"font-weight: 400;\">What are the main differences between phendimetrazine and phentermine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The main differences between <\/span><span style=\"font-weight: 400;\">phendimetrazine<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">phentermine<\/span><span style=\"font-weight: 400;\"> are in their available forms, dosages, and restrictions.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Dosages\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine, also known as phendimetrazine tartrate, is available as a 35 mg tablet and <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/018074s034lbl.pdf\"><span style=\"font-weight: 400;\">105 mg extended-release capsule<\/span><\/a><span style=\"font-weight: 400;\">. The usual dosage of phendimetrazine is a 35 mg tablet two to three times daily one hour before meals or a 105 mg extended-release capsule once in the morning 30 minutes to an hour before breakfast.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Phentermine is available as a regular oral tablet, capsule, extended-release capsule, and orally disintegrating tablet. Phentermine is available in strengths ranging from 15 to 37.5 mg, depending on the dosage form. There are also 8 mg tablets available under the brand name Lomaira, which can be taken up to three times daily 30 minutes before meals. The usual phentermine dosage is a 37.5 mg tablet one to two hours before breakfast.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Controlled substance schedules<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Another key difference between phendimetrazine and phentermine is their classification as <\/span><span style=\"font-weight: 400;\">controlled substances<\/span><span style=\"font-weight: 400;\">. Phendimetrazine is classified as a Schedule III controlled substance, while phentermine is classified as a Schedule IV controlled substance. This means that phendimetrazine has a higher potential for abuse and dependence than phentermine.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Age limits<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There are slight differences in the age limits for each drug. Both drugs may be prescribed for people with obesity with a body mass index (BMI) of 30 or higher and people who are overweight with a BMI of 27 or higher with weight-related medical conditions. However, phendimetrazine is FDA approved for adults and children 17 years or older, while phentermine is FDA approved for adults and children 16 years or older.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Anorectic<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sympathomimetic<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Stimulant<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Anorectic<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sympathomimetic<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Stimulant<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Generic version available<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic available<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the brand name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Bontril, Bontril PDM, Melfiat, Prelu-2, and others<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adipex-P, Lomaira, and others<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet, oral capsule, extended-release capsule<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet, oral capsule, extended-release capsule, orally disintegrating tablet<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">35 mg 2 to 3 times daily 1 hour before meals or 105 mg once every morning before breakfast<\/span><\/td>\n<td><span style=\"font-weight: 400;\">15 to 37.5 mg by mouth every morning before breakfast<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Short-term use, not more than a few weeks at a time, according to clinical studies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Short-term use, up to 12 weeks at a time, according to clinical studies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children 17 years of age and older with a BMI of 30 or higher or a BMI of 27 or higher with weight-related medical conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children 16 years of age and older with a BMI of 30 or higher or a BMI of 27 or higher with weight-related medical conditions<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated\"><span style=\"font-weight: 400;\">Conditions treated by phendimetrazine and phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are used to treat obesity, which is defined as a BMI of 30 or higher. These drugs may also be prescribed for individuals who are overweight that have a BMI of 27 or higher and weight-related medical conditions, such as high blood pressure, diabetes, and high cholesterol. Phendimetrazine and phentermine are not intended for use in people who only need to lose a few pounds.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">These medications are believed to work by decreasing appetite. They may also affect certain transmitters or chemicals in the central nervous system (CNS), such as dopamine and norepinephrine.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Weight reduction for people with obesity (BMI of 30 kg\/m2 or higher)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Weight reduction for people who are overweight (BMI of 27 kg\/m2 or higher) with weight-related conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"efficacy\"><span style=\"font-weight: 400;\">Is phendimetrazine or phentermine more effective?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are both effective options for <\/span><span style=\"font-weight: 400;\">short-term weight loss<\/span><span style=\"font-weight: 400;\"> when used along with a reduced-calorie diet and exercise program. There have been no head-to-head clinical studies that compare the effectiveness of phendimetrazine and phentermine. However, according to their prescription labels, phendimetrazine and phentermine are effective when compared to a placebo. The degree of weight loss is greatest in the first few weeks of treatment and may decrease over time.\u00a0\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.ajmc.com\/view\/review-of-current-guidelines-for-the-treatment-of-obesity\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Obesity treatment guidelines<\/span><\/a><span style=\"font-weight: 400;\"> recommend starting with lifestyle changes, such as an appropriate exercise regimen, healthy meal plan, and behavioral therapy. Prescription drugs may be considered if lifestyle changes aren\u2019t enough to reduce body weight.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consult a healthcare provider to determine the most effective treatment option. The best option will depend on your overall medical condition and other medications you may be taking, including prescription drugs, over-the-counter medicines, and herbal supplements. In some cases, a healthcare provider may recommend an <\/span><span style=\"font-weight: 400;\">alternative to phentermine<\/span><span style=\"font-weight: 400;\"> or phendimetrazine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<\/p>\n<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span><\/p><\/div>\n<p>\t<\/span><\/p>\n<h2 id=\"coverage-and-cost-comparison\"><span style=\"font-weight: 400;\">Coverage and cost comparison of phendimetrazine vs. phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are generic prescription drugs that may not be covered by most insurance and Medicare plans. The cost of these medications with insurance or Medicare will vary by plan.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Without insurance, these medications can be expensive. However, the retail cost will depend on the pharmacy and the quantity prescribed. A  <\/span><span style=\"font-weight: 400;\">phendimetrazine coupon<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">phentermine coupon<\/span><span style=\"font-weight: 400;\"> may help lower the retail price of these medications.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">90, 35 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">30, 37.5 mg tablets<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typical Medicare copay<\/b><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<\/tr>\n<tr>\n<td><b> cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$3<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$6<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"side-effects\"><span style=\"font-weight: 400;\">Common side effects of phendimetrazine vs. phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine share many of the same <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\">. As stimulant medications, they can cause high blood pressure, palpitations (pounding heart), and an increased heart rate. Both drugs can also cause headaches, insomnia (trouble sleeping), dizziness, and gastrointestinal side effects, such as <\/span><span style=\"font-weight: 400;\">diarrhea<\/span><span style=\"font-weight: 400;\"> and constipation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both medications may cause serious side effects, including chest pain, swelling of the legs or ankles, irregular heartbeat, and mental or mood changes. Signs or symptoms of an allergic reaction may include hives, rash, swelling of the throat, or difficulty breathing. Individuals who experience any of these symptoms should seek medical attention immediately.<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><b>Side Effect<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">High blood pressure<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Palpitations<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Increased heart rate<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Restlessness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dizziness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Headache<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Insomnia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dry mouth<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Diarrhea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Constipation<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Changes in libido<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><i><span style=\"font-weight: 400;\">This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more.<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">Source: DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4a64fde2-1db7-5878-e054-00144ff8d46c\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Phendimetrazine<\/span><\/a><span style=\"font-weight: 400;\">), DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/lookup.cfm?setid=3b44d104-a7d0-4366-9d42-63f784f3cb22\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Phentermine<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/p>\n<h2 id=\"interactions\"><span style=\"font-weight: 400;\">Drug interactions of phendimetrazine vs. phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine have identical drug interactions. They can both interact with <\/span><span style=\"font-weight: 400;\">monoamine oxidase inhibitors<\/span><span style=\"font-weight: 400;\"> (MAOIs), alcohol, antidiabetic medications, and adrenergic neuron blockers. Phendimetrazine or phentermine should not be used while taking or within 14 days of taking a MAOI due to the risk of hypertensive crisis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because of their effects on blood pressure, phendimetrazine and phentermine may alter the blood pressure-lowering effects of adrenergic neuron blockers. In addition, people with diabetes may need to reduce their dosage of insulin or other antidiabetic medications while taking phendimetrazine or phentermine.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Isocarboxazid<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Phenelzine<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Selegiline<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tranylcypromine<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">MAOIs<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Alcohol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Alcohol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Insulin<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Glipizide<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Glyburide<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sitagliptin<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dapagliflozin<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antidiabetic medications<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Guanethidine<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bethanidine<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bretylium<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Adrenergic neuron blockers<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><i><span style=\"font-weight: 400;\">Consult a healthcare professional for other possible drug interactions<\/span><\/i><\/p>\n<h2 id=\"warnings\"><span style=\"font-weight: 400;\">Warnings of phendimetrazine and phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine have identical warnings and precautions. They also share similar contraindications. Neither drug should be used in people that have a medical history of the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treatment with an MAOI currently or within the past 14 days<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hyperthyroidism<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Substance use disorder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Currently pregnant or breastfeeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergies to the medication<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Pulmonary hypertension (high blood pressure in the lungs) and valvular heart disease have been reported in people taking phendimetrazine or phentermine. Risk factors for these health problems include long-term use of anorectics, taking higher than the recommended dosage, and combining more than one anorectic agent.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Taking phendimetrazine or phentermine may impair an individual\u2019s ability to drive or operate machinery. Both medications may also be habit-forming. Therefore, abruptly stopping phendimetrazine or phentermine may increase the risk of withdrawal symptoms, such as depression and fatigue.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consult a healthcare provider for other warnings and precautions before starting treatment with an anorectic.\u00a0<\/span><\/p>\n<h2 id=\"faqs\"><span style=\"font-weight: 400;\">Frequently asked questions about phendimetrazine vs. phentermine<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">What is phendimetrazine?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine is a prescription medication used for weight loss. It is an anorectic or appetite suppressant that helps decrease appetite. The recommended dosage is usually 35 mg before meals or 105 mg taken once per day. Brand names include Bontril and Bontril PDM.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">What is phentermine?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phentermine is a prescription medication used for weight loss. It is an anorectic or appetite suppressant that helps decrease appetite. The recommended dose is usually 15 to 37.5 mg taken before breakfast. Brand names include Adipex-P and Lomaira.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Are phendimetrazine and phentermine the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are both prescription medications that are part of the same drug class called anorectics. They can help manage weight in people who are obese or overweight. However, they are not the same drug. For example, they have different dosage forms and age restrictions.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is phendimetrazine or phentermine better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Both phendimetrazine and phentermine are FDA-approved medications used as appetite suppressants, and the amount of weight that can be lost varies from person to person. Seek professional medical advice when determining the best option for your condition. These medications are most effective when used along with a healthy diet and lifestyle changes.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use phendimetrazine or phentermine while pregnant?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine and phentermine are not recommended for use during pregnancy due to a risk of harm to an unborn baby. If you are pregnant or have concerns about becoming pregnant, you should consult your doctor for more information.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use phendimetrazine or phentermine with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drinking alcoholic beverages while taking phendimetrazine or phentermine can increase the risk of severe side effects, such as dizziness, drowsiness, and impaired judgment. It is important to avoid alcohol while taking these medications.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Does phendimetrazine give you energy?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine may increase energy levels as it stimulates the central nervous system. However, it is not intended to be used as an energy booster. Phendimetrazine should only be used as directed by a healthcare provider.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">How long can you stay on phendimetrazine?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phendimetrazine is only recommended for short-term use. It is not intended for long-term use due to potential health risks. 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                       <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do you know: Phendimetrazine vs. phentermine: Differences, similarities, and which is better for you in 2025 Key takeaways Phendimetrazine and phentermine are prescription weight-loss medications that work as appetite suppressants and are used to treat obesity, but they differ in dosage forms, age restrictions, and controlled substance classifications. Both medications are recommended for short-term use [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5276","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5276","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=5276"}],"version-history":[{"count":1,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5276\/revisions"}],"predecessor-version":[{"id":5812,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5276\/revisions\/5812"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=5276"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=5276"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=5276"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}