{"id":5433,"date":"2024-12-08T05:15:55","date_gmt":"2024-12-08T05:15:55","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/?p=5433"},"modified":"2024-12-08T05:15:55","modified_gmt":"2024-12-08T05:15:55","slug":"hmn-foods-to-avoid-when-taking-lamotrigine-in-2024","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-foods-to-avoid-when-taking-lamotrigine-in-2024\/","title":{"rendered":"HMN: Foods to avoid when taking lamotrigine in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Foods to avoid when taking lamotrigine in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">There are no known drug-food interactions with lamotrigine.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">It\u2019s a good idea to avoid sugary foods, aspartame, caffeine, and alcohol while on lamotrigine because these foods may exacerbate symptoms of epilepsy or bipolar disorder.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Many providers also suggest avoiding grapefruit and grapefruit juice while taking prescription medications because this fruit can impact metabolism and influence the drug levels in your body.\u00a0<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">While on lamotrigine, focus on eating a low-sugar, nutrient-dense, healthy diet. A healthy diet is beneficial for overall health.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Lamotrigine is a prescription drug used to <\/span><span style=\"font-weight: 400;\">treat epilepsy<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><span style=\"font-weight: 400;\">. Some providers also prescribe this drug <\/span><span style=\"font-weight: 400;\">off-label<\/span><span style=\"font-weight: 400;\"> for migraine prevention. Lamotrigine is the generic form of brand-name drugs <\/span><span style=\"font-weight: 400;\">Lamictal<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Lamictal XR<\/span><span style=\"font-weight: 400;\"> (an extended-release form of lamotrigine) by pharmaceutical manufacturer GlaxoSmithKline (GSK).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like most drugs, <\/span><span style=\"font-weight: 400;\">lamotrigine<\/span><span style=\"font-weight: 400;\"> has risks and side effects. There are no specific drug-food interactions with lamotrigine, but you may want to avoid foods that could trigger seizures, impede drug absorption, or exacerbate side effects. Consider limiting or avoiding grapefruit, sugary foods, aspartame, caffeine, and alcohol.<\/span><\/p>\n<h2 id=\"how-lamotrigine-works\"><span style=\"font-weight: 400;\">How lamotrigine works<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201c[Lamotrigine] lessens the release of glutamate, the substance that stimulates brain activity,\u201d explains <\/span><a href=\"https:\/\/www.digestivereset.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Inna Melamed<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., a functional medicine practitioner and author of <\/span><a href=\"https:\/\/www.amazon.com\/Digestive-Reset-Digestion-Balancing-Microbiome\/dp\/1690800739\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Digestive Reset<\/span><\/i><\/a><span style=\"font-weight: 400;\">. In other words, lamotrigine works by slowing down nerve activity, which can control seizures and act as a <\/span><span style=\"font-weight: 400;\">mood stabilizer<\/span><span style=\"font-weight: 400;\">. According to Dr. Melamed, when you first start the medication, it may take about six weeks to get the full therapeutic effects.<\/span><\/p>\n<h2 id=\"5-foods-to-avoid-with-lamotrigine\"><span style=\"font-weight: 400;\">5 foods to avoid with lamotrigine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cThere are no known interactions with food and lamotrigine,\u201d says <\/span><a href=\"http:\/\/thepublichealthpharmacist.com\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Christina Madison, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, founder of The Public Health Pharmacist. However, certain foods may still affect your successful treatment with lamotrigine. If you\u2019re on lamotrigine, it\u2019s a good idea to avoid foods that may trigger seizures, worsen side effects, or impede the absorption of your medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The list below outlines the foods to avoid or limit while taking anticonvulsants such as lamotrigine.<\/span><\/p>\n<h3 id=\"1-grapefruit-juice\"><span style=\"font-weight: 400;\">1. Grapefruit juice<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Experts agree: Grapefruit and grapefruit juice are among the <\/span><span style=\"font-weight: 400;\">foods you shouldn\u2019t mix with medicine<\/span><span style=\"font-weight: 400;\">. According to the <\/span><a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/grapefruit-juice-and-some-drugs-dont-mix\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">U.S. Food &amp; Drug Administration (FDA)<\/span><\/a><span style=\"font-weight: 400;\">, this citrus fruit can affect how the body metabolizes drugs resulting in unsafe levels of the drug in your body.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cEven though no direct interaction has been noted between grapefruit and lamotrigine, it\u2019s best to be cautious,\u201d says Dr. Melamed. \u201cGrapefruit is known to interact with other medications used for epilepsy or bipolar disorders.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Of course, grapefruit is not the only food that doesn\u2019t mix well with drugs. Other commonly suggested foods to avoid mixing with medications include dairy (cheese and milk), bananas, and black licorice. However, <\/span><i><span style=\"font-weight: 400;\">none<\/span><\/i><span style=\"font-weight: 400;\"> of these drugs are contraindicated with lamotrigine. You may limit them out of an abundance of caution, or you can talk to your doctor about dietary restrictions specific to your medications and conditions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<\/p>\n<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span><\/p><\/div>\n<p>\t<\/span><\/p>\n<h3 id=\"2-sugary-foods-and-drinks\"><span style=\"font-weight: 400;\">2. Sugary foods and drinks<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some healthcare providers advise patients with epilepsy to avoid or limit high-sugar foods and beverages. That\u2019s because <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC387262\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">high blood sugar levels have been associated with an increased risk of seizures<\/span><\/a><span style=\"font-weight: 400;\"> in at least one form of epilepsy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">From the low glycemic index diet to the ketogenic diet, mainstream <\/span><a href=\"https:\/\/nyulangone.org\/conditions\/epilepsy-seizure-disorders\/treatments\/dietary-therapies-for-epilepsy-seizure-disorders\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">dietary therapies for epilepsy<\/span><\/a><span style=\"font-weight: 400;\"> often involve decreasing sugar consumption. The exact reason why is not fully understood, but foods that quickly raise blood sugar, causing energy spikes followed by slumps, can be problematic for people with epilepsy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While some people with epilepsy find that low-sugar diets like keto or a modified Atkins help reduce symptoms, it\u2019s a good idea to consult your healthcare provider before going on a specialized diet.<\/span><\/p>\n<h3 id=\"3-aspartame\"><span style=\"font-weight: 400;\">3. Aspartame<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aspartame is an artificial sweetener found in diet sodas, sugar-free gum, and \u201cmany other \u2018low-calorie\u2019 foods,\u201d says Dr. Melamed. Due to potential neurophysiological effects, she advises limiting aspartame if you\u2019re taking lamotrigine for seizures.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Indeed, <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28198207\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">aspartame has been linked to seizures<\/span><\/a><span style=\"font-weight: 400;\">, though more research is needed to understand the connection entirely. A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10459792\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">recent report in the scientific journal <\/span><i><span style=\"font-weight: 400;\">Nutrients<\/span><\/i><\/a> <span style=\"font-weight: 400;\">stated that the research suggests that aspartame \u201cmay pose some dangers\u201d in patients with seizures or other neurological diseases.<\/span><\/p>\n<h3 id=\"4-caffeine\"><span style=\"font-weight: 400;\">4. Caffeine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Caffeine does not interact with lamotrigine, but it may exacerbate bipolar disorder symptoms such as agitation, irritability, restlessness, and trouble sleeping. In large amounts, <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29414557\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">caffeine may also increase seizure susceptibility<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People with bipolar disorder are usually advised to avoid this stimulant. Still, a scientific review of 17 studies found that the effects of <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32949106\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">caffeine<\/span><\/a><span style=\"font-weight: 400;\"> in patients with bipolar disorder are still not fully understood. Caffeine may trigger manic symptoms in some patients, but it could also be that manic symptoms like impulsivity lead to an increase in caffeine intake.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ultimately, it\u2019s a good idea to get medical advice from a healthcare professional before consuming caffeine with your dose of lamotrigine. Please be aware that caffeine doesn\u2019t only come from coffee. Drinks and foods high in caffeine include chocolate, kola nut, tea, and yerba mate.<\/span><\/p>\n<h3 id=\"5-alcohol\"><span style=\"font-weight: 400;\">5. Alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There are no known interactions between alcohol and lamotrigine, but drinking alcohol can exacerbate the nervous system side effects of this medication, says Dr. Melamed. Specifically, alcohol may worsen dizziness, drowsiness, and difficulty concentrating. Blurred vision and lack of coordination are also common <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of lamotrigine. These are also consequences of drinking alcohol, so mixing the two substances may increase the speed and severity of these side effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Overall, it\u2019s best to avoid, or at least limit, alcohol use with lamotrigine.<\/span><\/p>\n<h2 id=\"herbs-and-supplements-to-avoid-with-lamotrigine\"><span style=\"font-weight: 400;\">Herbs and supplements to avoid with lamotrigine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cThere are no specific interactions with herbal products or supplements and lamotrigine,\u201d says Dr. Madison. \u201cHowever, if someone is taking multiple vitamins or supplements, they could possibly interact with each other.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though lamotrigine has no known negative interactions with herbs or supplements, there are potentially dangerous drug-drug interactions. Combining lamotrigine with amifampridine, <\/span><span style=\"font-weight: 400;\">dalfampridine<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">Wellbutrin<\/span><span style=\"font-weight: 400;\"> (bupropion), or <\/span><span style=\"font-weight: 400;\">metoclopramide <\/span><span style=\"font-weight: 400;\">can increase the risk of seizures. Other drugs may be combined with lamotrigine, but only at certain doses and under close supervision by a healthcare provider. These include certain birth control pills, anticonvulsants (such as <\/span><span style=\"font-weight: 400;\">carbamazepine<\/span><span style=\"font-weight: 400;\">), antidepressants, antipsychotics, sedatives, muscle relaxants, and other central nervous system depressants.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bottom line: Speak with your healthcare provider about any dietary supplements or over-the-counter or prescription meds you\u2019re taking. That way, they can make you aware of any potential interactions when prescribing lamotrigine or other medications.<\/span><\/p>\n<h2 id=\"what-should-you-eat-while-taking-lamotrigine\"><span style=\"font-weight: 400;\">What should you eat while taking lamotrigine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are no specific foods that will boost lamotrigine\u2019s efficacy, but what you eat while taking lamotrigine still matters. In many ways, it\u2019s more important to focus on what you <\/span><i><span style=\"font-weight: 400;\">should<\/span><\/i><span style=\"font-weight: 400;\"> eat rather than what you should avoid. And what you should eat is a healthy diet.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to filling your plate with <\/span><span style=\"font-weight: 400;\">foods that support mental health<\/span><span style=\"font-weight: 400;\">, like lean meats, fresh produce, and whole grains, you can prioritize foods that won\u2019t spike your blood sugar. These foods\u2014known as <\/span><span style=\"font-weight: 400;\">low glycemic index foods<\/span><span style=\"font-weight: 400;\">\u2014include eggs, apples, bananas, and Greek yogurt.<\/span><\/p>\n<h2 id=\"gastrointestinal-side-effects-of-lamotrigine\"><span style=\"font-weight: 400;\">Gastrointestinal side effects of lamotrigine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common gastrointestinal adverse effects of lamotrigine include nausea, vomiting, sore throat, and dry mouth. A few of these common side effects may be exacerbated by the foods mentioned above, which is another reason to consider monitoring your diet. For instance, acidic or carbonated drinks (such as grapefruit juice or sugary soda) may worsen a sore throat or nausea from heartburn.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s not always possible to avoid <\/span><span style=\"font-weight: 400;\">lamotrigine side effects<\/span><span style=\"font-weight: 400;\">. However, you may be able to reduce side effects by working with your provider to adjust your dosage. You can also reduce your risk of serious side effects by talking to your prescriber about your medical history, allergic reactions to previous medications, serious side effects (including suicidal thoughts) from previous medicines, pregnancy or plans to become pregnant, and breastfeeding or plans to breastfeed.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, always take lamotrigine as directed by your prescriber. 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It\u2019s a good idea to avoid sugary foods, aspartame, caffeine, and alcohol while on lamotrigine because these foods may exacerbate symptoms of epilepsy or bipolar disorder. Many providers also suggest avoiding grapefruit and grapefruit [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5433","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=5433"}],"version-history":[{"count":1,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5433\/revisions"}],"predecessor-version":[{"id":5468,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/5433\/revisions\/5468"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=5433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=5433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=5433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}