{"id":6935,"date":"2025-02-03T11:34:40","date_gmt":"2025-02-03T11:34:40","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-differences-similarities-side-effects-in-2025-8\/"},"modified":"2025-02-03T11:45:55","modified_gmt":"2025-02-03T11:45:55","slug":"hmn-differences-similarities-side-effects-in-2025-8","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-differences-similarities-side-effects-in-2025-8\/","title":{"rendered":"HMN: Xolair and Dupixent Differences, similarities &#038; side effects in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Differences, similarities &#038; side effects in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Xolair and Dupixent are both brand-name prescription injectable medications used to treat moderate to severe asthma and chronic rhinosinusitis with nasal polyps.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Xolair is also FDA approved to treat chronic hives and food allergies.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Dupixent is also FDA approved to treat atopic dermatitis, eosinophilic esophagitis, and prurigo nodularis.\u00a0<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Both drugs are monoclonal antibodies that help decrease the body\u2019s inflammatory response.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Though both of these medications are effective, Xolair may have a higher risk for allergic reactions and, potentially, cancer. Dupixent has a higher risk of side effects that affect the eyes.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">No single asthma or rhinosinusitis drug is the best one. Seek medical advice from your healthcare provider or pharmacist to find the best treatment.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Xolair<\/span><span style=\"font-weight: 400;\"> (omalizumab) and <\/span><span style=\"font-weight: 400;\">Dupixent<\/span><span style=\"font-weight: 400;\"> (dupilumab) are two brand-name injectable medications indicated for treating asthma, among other inflammatory or autoimmune conditions. They are classified in a group of drugs called monoclonal antibodies, a type of biologic.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cBiologics are complex medications that are typically made from DNA technology. Overall, biologics are an innovative treatment option for many rare or complex disease states,\u201d said <\/span><a href=\"https:\/\/www.linkedin.com\/in\/christina-bookwalter\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Christina Bookwalter, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, a clinical pharmacist practitioner in Minneapolis, Minnesota.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the case of Xolair and Dupixent, the biologics are antibodies, or protective proteins. They work by binding to the part of the immune system that causes allergic inflammation, said Jason M. Bellak, MD, an allergy\/immunology physician and president of <\/span><a href=\"http:\/\/katzallergy.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Allergy &amp; Asthma Center<\/span><\/a><span style=\"font-weight: 400;\"> in Las Vegas.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though similar in some ways, Xolair and Dupixent have notable differences in their ingredients and approved uses.<\/span><\/p>\n<h2 id=\"xolair-vs-dupixent-key-differences\"><span style=\"font-weight: 400;\">Xolair vs. Dupixent: Key differences<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xolair and Dupixent are both brand-name biologic injections, but they work differently. The main difference is their mechanism of action or the specific biochemical reaction they trigger in the body.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cXolair attaches to allergic antibodies called IgE antibodies, thereby decreasing allergic asthma, chronic hives, and food allergy reactions,\u201d Dr. Bellak explained. \u201cDupixent is an antibody to what is called the interleukin 4 receptor alpha chain that is shared with interleukin 13. Interleukin 4 and 13 are key pro-allergic inflammatory chemicals. By blocking those chemicals, Dupixent decreases allergic inflammation.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because they work somewhat differently, Xolair and Dupixent are also indicated for different types of asthma.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"xolair-vs-dupixent-comparing-key-differences\"><span class=\"title\">Xolair vs. Dupixent: Comparing key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Monoclonal antibody, biologic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Monoclonal antibody, biologic<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">omalizumab<\/span><\/td>\n<td><span style=\"font-weight: 400;\">dupilumab<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Auto-injector or pre-filled syringe or vial<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Pen-injector or prefilled syringe<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">75\u2013600 mg injection every 2 to 4 weeks depending on diagnosis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">200\u2013300 mg injection every other week depending on diagnosis<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long-term\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults, adolescents, and children ages 1 and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults, adolescents, and children ages 6 months and older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"xolair-vs-dupixent-conditions-treated\"><span style=\"font-weight: 400;\">Xolair vs. Dupixent: Conditions treated<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When comparing <\/span><a href=\"https:\/\/www.xolair.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Xolair<\/span><\/a><span style=\"font-weight: 400;\"> versus <\/span><a href=\"https:\/\/www.dupixent.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dupixent<\/span><\/a><span style=\"font-weight: 400;\">, it is also essential to know that they are approved to treat different but overlapping conditions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThey are both approved for the treatment of chronic sinusitis with nasal polyps in adults,\u201d Dr. Bellak said. They\u2019re also both approved for the treatment of moderate-severe asthma for people ages 6 and older, but Xolair is specifically approved to treat allergic asthma, while Dupixent is approved to treat severe eosinophilic asthma, which occurs when white blood cells called eosinophils cause airway inflammation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beyond that overlap, Xolair is approved by the Food and Drug Administration (FDA) to treat chronic spontaneous urticaria (CSU)\u2014previously referred to as chronic idiopathic urticaria (CIU)\u2014the medical term for hives with no cause. In 2024, the <\/span><span style=\"font-weight: 400;\">FDA also approved Xolair for accidental exposure<\/span><span style=\"font-weight: 400;\"> in people with food allergies.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dupixent, on the other hand, is FDA-approved for use in the treatment of eczema, medically known as atopic dermatitis (AD), eosinophilic esophagitis, and prurigo nodularis, a chronic skin disorder.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In many cases, these biologics are only approved for severe cases of the above conditions or cases in which first-line treatments\u2014such as an inhaler for asthma\u2014have not effectively controlled symptoms.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"xolair-vs-dupixent-comparing-conditions-treated\"><span class=\"title\">Xolair vs. Dupixent: Comparing conditions treated<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Asthma<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Chronic hives with no known cause<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Food allergies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Chronic rhinosinusitis with nasal polyps<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Eczema (atopic dermatitis)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Eosinophilic esophagitis\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Prurigo nodularis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"dupixent-vs-xolair-which-is-better\"><span style=\"font-weight: 400;\">Dupixent vs. Xolair: Which is better?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Even in a head-to-head comparison of Xolair versus Dupixent, there is no clear winner. The two drugs are both effective, but they treat different conditions.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Placebo-controlled <\/span><a href=\"https:\/\/www.dupixenthcp.com\/asthma\/efficacy\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\"> funded by Sanofi, one of the manufacturers of Dupixent, show that Dupixent treatment in asthma patients ages 12 and older reduced severe exacerbations by 81% and improved overall asthma control and quality of life.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A 16-year clinical trial follow-up of the effectiveness of Xolair (omalizumab) published in the <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9039243\/\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Journal of Asthma and Allergy<\/span><\/i><\/a><span style=\"font-weight: 400;\"> showed that Xolair is effective at reducing the incidence of severe asthma over the long term. Patient scores from baseline to follow-up significantly improved on the Asthma Quality of Life Questionnaire (AQLQ) and Asthma Control Test (ACT)\u2014two standardized measurements of asthma symptom control.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ultimately, both Dupixent and Xolair have proven effective at improving symptoms of severe asthma. Dr. Bellak says determining the best medication for conditions treated by Dupixent and Xolair is complicated and requires a \u201cglobal\u201d evaluation by an allergist or immunology specialist. A prescribing doctor will consider the patient\u2019s current medical condition, medical history, laboratory data, allergy test results, other medications that could interact with Xolair or Dupixent, and patient preferences.<\/span><\/p>\n<h2 id=\"can-you-take-xolair-and-dupixent-together\"><span style=\"font-weight: 400;\">Can you take Xolair and Dupixent together?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cBiologic medications have not been studied together, and there is no FDA indication to use more than one biologic medication in patients,\u201d Dr. Bellak said. He adds that in rare cases, a healthcare provider may consider using Xolair and Dupixent together, but that would be a discussion between the doctor and patient.\u00a0<\/span><\/p>\n<h2 id=\"xolair-vs-dupixent-insurance-coverage-and-cost-comparison\"><span style=\"font-weight: 400;\">Xolair vs. Dupixent: Insurance coverage and cost comparison<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Without insurance, the average retail price of <\/span><span style=\"font-weight: 400;\">Xolair<\/span><span style=\"font-weight: 400;\"> is about $4,020 for two 1-milliliter (ml) syringes, and <\/span><span style=\"font-weight: 400;\">Dupixent<\/span><span style=\"font-weight: 400;\"> costs around $5,150 for two 2 ml pens. The amounts would usually cover a one-month supply for asthma treatment. Medication prices vary by pharmacy and insurance plan.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cDue to the high cost of these medications, insurance coverage is an important point to consider,\u201d Dr. Bookwalter said. \u201cTypically, these medications require a prior authorization from the doctor before they are covered by insurance.\u201d<\/span><\/p>\n<p><a href=\"https:\/\/www.linkedin.com\/in\/blair-gingerich-622867280\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Blair Gingerich, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, an ambulatory care pharmacist in northern Indiana, explains that insurance companies require information from the doctor to authorize payment because drugs like Xolair and Dupixent are expensive and reserved for very specific diseases. \u201cIf they aren\u2019t covered, patients can discuss other options with their provider,\u201d she added. \u201cOften, there are manufacturer coupons that are available, but eligibility for coupon use varies.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cash payers can also save money on Xolair and Dupixent with a <\/span><span style=\"font-weight: 400;\"> prescription discount card<\/span><span style=\"font-weight: 400;\">. The card provides access to coupons at participating pharmacies that could reduce the cost of Xolair to about $2,730 and the cost of Dupixent to about $3,600.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"xolair-vs-dupixent-comparing-insurance-cost\"><span class=\"title\">Xolair vs. Dupixent: Comparing insurance &amp; cost<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Depends on plan<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Depends on plan<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">2, 1 ml pre-filled syringes<\/span><\/td>\n<td><span style=\"font-weight: 400;\"> 2, 2 ml pre-filled injector pens<\/span><\/td>\n<\/tr>\n<tr>\n<td><b> cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$2,730<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$3,600<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h2 id=\"xolair-vs-dupixent-side-effects\"><span style=\"font-weight: 400;\">Xolair vs. Dupixent side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xolair and Dupixent are biologic injections but have different side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most common side effects of Xolair are injection site reactions, joint stiffness, and body aches. The most common <\/span><span style=\"font-weight: 400;\">side effects of Dupixent<\/span><span style=\"font-weight: 400;\"> are a reaction at the injection site and conjunctivitis, also known as pink eye.<\/span><\/p>\n<p><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/103976s5238lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Xolair\u2019s drug label<\/span><\/a><span style=\"font-weight: 400;\"> includes a disclaimer that an omalizumab injection may cause a serious or life-threatening allergic reaction. Seek help immediately if you have trouble breathing, break out in hives, or feel dizzy or faint after a Xolair injection. Other serious side effects of Xolair include cancer, inflammation of blood vessels, parasitic infection, heart problems, and a combination of fever, muscle aches, and rash. Report these uncommon but severe side effects to your doctor immediately.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Severe Dupixent side effects include an allergic reaction, eye problems, and joint pain so severe that it impedes mobility.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The following table lists side effects reported in at least 2% of clinical trial participants for Xolair or Dupixant. The adverse effect frequency listed on each drug\u2019s label varies depending on the patient population in each study, and comparisons between the two drugs are imperfect without a head-to-head comparison study regarding side effects. Consult a healthcare professional for a complete list of side effects.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"xolair-vs-dupixent-comparing-side-effects\"><span class=\"title\">Xolair vs. Dupixent: Comparing side effects<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Arthralgia (joint stiffness)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Body aches<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">7%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Leg pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Fatigue<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dizziness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Fracture<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Arm pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Pruritus (itchy skin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dermatitis (skin irritation or inflammation)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Earache<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Injection site reaction<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%\u201345%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">6%\u201338%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Conjunctivitis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Oral herpes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Other herpes simplex virus infection<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2014<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><span style=\"font-weight: 400;\">Source: Daily Med (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=7f6a2191-adfb-48b9-9bfa-0d9920479f0d\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Xolair<\/span><\/a><span style=\"font-weight: 400;\">) (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/lookup.cfm?setid=595f437d-2729-40bb-9c62-c8ece1f82780\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dupixent<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/h5>\n<h2 id=\"xolair-and-dupixent-drug-interactions\"><span style=\"font-weight: 400;\">Xolair and Dupixent drug interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">According to the drugs\u2019 labels, there are no known adverse drug interactions between Xolair and other medications, nor for Dupixent and other medications. However, it is still essential to give your healthcare provider a list of all the medicines and supplements you take before starting one of these injections.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As a general rule, taking more than one biologic therapy at the same time is not recommended. That includes <\/span><a href=\"https:\/\/www.cdc.gov\/vaccines\/pubs\/pinkbook\/downloads\/prinvac.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">live vaccines<\/span><\/a><span style=\"font-weight: 400;\"> such as MMR, varicella, rotavirus, and the intranasal flu vaccine. Other biologic therapies for severe eosinophilic asthma or severe allergic asthma include Nucala (mepolizumab) and Fasenra (benralizumab).<\/span><\/p>\n<p><strong> Important information about Dupixent and vaccines<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s very important to keep taking your other prescription medications while on Xolair or Dupixent. Though these are FDA-approved asthma treatments, they are not a substitute for a steroid inhaler, also called a corticosteroid inhaler. These injections are long-acting and do not provide emergency relief for poor lung function.<\/span><\/p>\n<h2 id=\"xolair-and-dupixent-drug-warnings\"><span style=\"font-weight: 400;\">Xolair and Dupixent drug warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xolair and Dupixent are not the right medications for everyone. It is important to weigh the risks against the benefits and seek medical advice from a healthcare provider who understands your medical conditions and history.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because malignancy has been observed in clinical studies, Xolair may not be recommended for patients with cancer or a history of cancer. It may also not be recommended for patients with eosinophilia, vasculitic rash, or heart problems. The needle cap on Xolair\u2019s prefilled syringe is latex, so this medication may not be recommended to people with latex allergies. And, of course, it is not safe for anyone allergic to omalizumab, the active ingredient in Xolair.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dupixent does not have the warning for anaphylaxis that Xolair does. However, Dupixent may still cause serious side effects, including eye problems. 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Xolair is also FDA approved to treat chronic hives and food allergies. Dupixent is also FDA approved to treat atopic dermatitis, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-6935","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/6935","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=6935"}],"version-history":[{"count":1,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/6935\/revisions"}],"predecessor-version":[{"id":6969,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/6935\/revisions\/6969"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=6935"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=6935"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=6935"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}