{"id":7034,"date":"2025-02-03T12:10:01","date_gmt":"2025-02-03T12:10:01","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-take-cyclobenzaprine-with-tramadol-in-2025\/"},"modified":"2025-02-03T12:10:01","modified_gmt":"2025-02-03T12:10:01","slug":"hmn-can-you-take-cyclobenzaprine-with-tramadol-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-take-cyclobenzaprine-with-tramadol-in-2025\/","title":{"rendered":"HMN: Can you take cyclobenzaprine with tramadol? in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Can you take cyclobenzaprine with tramadol? in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine is a muscle relaxer prescribed primarily to treat spasms, while tramadol is an opioid used for short-term acute pain relief.\u00a0<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Both drugs act on the central nervous system, and together, they may cause CNS depression\u2014a condition that could cause a range of medical problems, including respiratory depression and coma.\u00a0<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Taking both drugs in low doses together may be necessary for the short-term treatment of severe spasms and pain.\u00a0<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Only take the drugs together with a healthcare provider\u2019s approval, and follow their exact schedule, recommended dose, and medical advice.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine<\/span><span style=\"font-weight: 400;\">, known by the brand name Flexeril, is a muscle relaxant that can treat spasms, discomfort, and stiffness throughout the body, often from injuries. <\/span><span style=\"font-weight: 400;\">Tramadol<\/span><span style=\"font-weight: 400;\"> is an opioid pain reliever used for treating severe pain. These two prescription drugs might seem like they\u2019d go hand-in-hand, but taking them together can have a significant effect on the central nervous system, potentially leading to some serious side effects. Before combining medications, please continue reading for important information.<\/span><\/p>\n<h2 id=\"can-you-take-tramadol-and-cyclobenzaprine-together\"><span style=\"font-weight: 400;\">Can you take tramadol and cyclobenzaprine together?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In certain situations, it could be dangerous to take tramadol and cyclobenzaprine at the same time, so doctors often use them carefully, particularly for older adults. Because both drugs affect the central nervous system, they can have an additive effect when used together, according to <\/span><a href=\"https:\/\/www.linkedin.com\/in\/paul-daidone-md-fasam-24556b72\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dr. Paul Daidone, MD, FASAM<\/span><\/a><span style=\"font-weight: 400;\">, medical director of <\/span><a href=\"https:\/\/trueselfrecovery.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">True Self Recovery<\/span><\/a><span style=\"font-weight: 400;\">. \u201cThe concurrent use of tramadol and cyclobenzaprine is not outright contraindicated,\u201d he says. \u201cBut it requires a cautious approach.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. John Lowe, MD of <\/span><a href=\"https:\/\/www.restorecare.org\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Restore Care Wellness Clinic<\/span><\/a><span style=\"font-weight: 400;\"> agrees, stating, \u201cCombining the synthetic opioid analgesic tramadol and cyclobenzaprine, a muscle relaxant, raises legitimate concerns due to possible additive central nervous system depression.\u201d Central nervous system depression is when the body\u2019s neurological processes slow down, affecting breathing, heart rate, blood pressure, and more.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Higher doses often pose a higher risk, so \u201cgenerally, doctors aim to start with the lowest effective dose for each medication to minimize the risk of adverse effects while still achieving therapeutic benefit,\u201d Dr. Lowe says. However, \u201cthe specific dosage regimen can vary widely among patients, and it\u2019s essential for healthcare providers to carefully assess and monitor each patient\u2019s response to treatment to adjust the dosage as needed.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The United States Drug Enforcement Agency has classified tramadol as a <\/span><a href=\"https:\/\/www.dea.gov\/drug-information\/drug-scheduling\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">class IV controlled substance<\/span><\/a><span style=\"font-weight: 400;\">, which means it also has a risk (albeit a relatively low one) of abuse, dependence, and withdrawal symptoms. That\u2019s why it\u2019s most often used for the short-term treatment of acute pain. It\u2019s not typically recommended for chronic pain, but healthcare professionals might still prescribe it for a longer duration of use in rare situations.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So yes, technically, you can take them together, but only when a health care professional prescribes it. And you have to follow their instructions exactly.\u00a0<\/span><\/p>\n<h2 id=\"what-happens-if-you-take-tramadol-and-cyclobenzaprine-together\"><span style=\"font-weight: 400;\">What happens if you take tramadol and cyclobenzaprine together?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As CNS depressants, both drugs significantly slow down certain central nervous system functions. Unlike many muscle relaxants, cyclobenzaprine acts directly on the brain stem rather than the muscles. Similar to some tricyclic antidepressants, it <\/span><a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/cyclobenzaprine\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">blocks certain motor neurons<\/span><\/a><span style=\"font-weight: 400;\"> to help relieve muscle spasms. On the other hand, tramadol inhibits<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15509185\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> norepinephrine and serotonin reuptake<\/span><\/a><span style=\"font-weight: 400;\"> while blocking certain opioid receptors to influence the body\u2019s pain response.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Together, those effects can produce some concerning adverse reactions. \u201cThe two drugs are both sedative agents, and, when taken concurrently, they will increase sedation, dizziness, weakness, or lack of balance,\u201d says Dr. Lowe. \u201cThis can lead to more accidents occurring, especially among those groups who are vulnerable, such as older populations or those with other conditions.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other <\/span><a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/central-nervous-system-depression\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">central nervous system side effects<\/span><\/a><span style=\"font-weight: 400;\"> may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slurred speech<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduced mental alertness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood changes\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slower heart rate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred or altered vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic reaction\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">For people who experience one or more of these reactions, the healthcare provider might recommend a dose adjustment or alternative medications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But there is another risk of taking cyclobenzaprine and tramadol together. Dr. Daidone adds, \u201cConcurrent use can also increase the risk of <\/span><span style=\"font-weight: 400;\">serotonin syndrome<\/span><span style=\"font-weight: 400;\">, a potentially life-threatening medical condition characterized by symptoms such as confusion, rapid heart rate, dilated pupils, fever, ataxia, stiff muscles, and more.\u201d In certain rare cases, severe central nervous system depression from taking these drugs together may cause seizures, respiratory distress, coma, and even death.\u00a0<\/span><\/p>\n<h3 id=\"precautions\"><span style=\"font-weight: 400;\">Precautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Each drug has certain precautions that every patient and their healthcare provider should assess. It\u2019s crucial for your healthcare provider to know your medical history, so before beginning<\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682514.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> cyclobenzaprine treatment<\/span><\/a><span style=\"font-weight: 400;\">, inform your care team if you\u2019ve had:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiac issues like heart failure, irregular heartbeat, or heart block<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Overactive thyroid<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty urinating<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Because tramadol is a controlled substance, its list of <\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a695011.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">precautions and warnings<\/span><\/a><span style=\"font-weight: 400;\"> is even longer. Inform the healthcare provider if you currently have or have had:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">COPD (since it can cause serious breathing issues)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Head injuries or brain tumors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Recent heart attack or other heart problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mental health conditions, including depression and addiction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blocking or narrowing of stomach\/intestines or paralytic ileus<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Brain or spine infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty urinating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pancreas, gallbladder, or thyroid issues<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney or liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upcoming surgery<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">On top of all that, anyone taking these drugs should cut out the use of alcohol. Alcoholic beverages are also depressants. Avoid driving or operating hazardous machinery while taking these medications. People who are pregnant, breastfeeding, or planning on getting pregnant should inform their healthcare provider since the drugs might affect unborn children.\u00a0<\/span><\/p>\n<h3 id=\"drug-interactions\"><span style=\"font-weight: 400;\">Drug interactions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">tramadol<\/span><span style=\"font-weight: 400;\"> both have major drug interaction warnings as well, most significantly with monoamine oxidase inhibitors (<\/span><span style=\"font-weight: 400;\">MAOIs<\/span><span style=\"font-weight: 400;\">) like Marplan and Nardil. Due to the seriousness of these interactions, cyclobenzaprine or tramadol should not be used within 14 days of taking MAO inhibitors. They may also interact with the following medicines:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other muscle relaxants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other narcotic pain medicines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain selective serotonin reuptake inhibitors (<\/span><span style=\"font-weight: 400;\">SSRIs<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other drugs that affect serotonin levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medications for sleep or anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Azole antifungals<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Macrolide antibiotics<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizure drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain nonprescription drugs like cough relievers or allergy medicines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some dietary supplements, natural products, or herbal products like St. John\u2019s wort.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Inform your healthcare provider about all medicines and supplements you\u2019re taking before beginning treatment.\u00a0<\/span><\/p>\n<h2 id=\"when-would-you-need-to-take-cyclobenzaprine-and-tramadol\"><span style=\"font-weight: 400;\">When would you need to take cyclobenzaprine and tramadol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Despite the long list of possible interactions, cyclobenzaprine and tramadol aren\u2019t totally incompatible. There are some specific situations where taking them together might be necessary.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Lowe, those situations include \u201cthe management of musculoskeletal pain conditions such as muscle spasms and certain types of chronic pain. Additionally, this combination might be utilized in postoperative settings, particularly for surgeries associated with significant musculoskeletal pain or muscle spasm.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">That\u2019s usually when someone hasn\u2019t had adequate pain relief with one drug alone or other drugs have already been tried, adds Dr. Daidone. \u201cThe goal would be to use the lowest effective doses for the shortest duration possible, with careful monitoring for adverse effects,\u201d he says.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Each person is different, so \u201cthe decision to co-administer these medications should be made on a case-by-case basis,\u201d according to Dr. Daidone. \u201cDoctors should evaluate the benefits against the risks and consider the individual patient\u2019s health status and concurrent medications.\u201d<\/span><\/p>\n<h2 id=\"is-it-safe-to-take-tramadol-and-cyclobenzaprine\"><span style=\"font-weight: 400;\">Is it safe to take tramadol and cyclobenzaprine?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It can be, but only in specific circumstances under the close supervision of the prescribing healthcare provider. Both drugs depress the central nervous system, and even though they have different functions, they can cause some serious\u2014even life-threatening\u2014issues when taken together. That\u2019s why it\u2019s crucial never to self-medicate. Instead, follow the exact instructions of your healthcare provider and pharmacist and seek medical help if anything seems off.\u00a0<\/span><\/p>\n<p><svg style=\"display:none\">\n  <g id=\"facebook\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M19.51 9.32003H21.39V6.14003C20.4798 6.04538 19.5652 5.99865 18.65 6.00003C15.93 6.00003 14.07 7.66003 14.07 10.7V13.32H11V16.88H14.07V26H17.75V16.88H20.81L21.27 13.32H17.75V11.05C17.75 10 18.03 9.32003 19.51 9.32003Z\"\/>\n  <\/g>\n  <g id=\"twitter\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M26 9.9506C25.2483 10.2767 24.4534 10.4923 23.64 10.5906C24.4982 10.0779 25.1413 9.27138 25.45 8.3206C24.6436 8.80066 23.7608 9.1389 22.84 9.3206C22.2245 8.65317 21.405 8.2089 20.5098 8.05745C19.6147 7.90601 18.6945 8.05596 17.8938 8.48379C17.093 8.91162 16.4569 9.59313 16.0852 10.4214C15.7135 11.2497 15.6273 12.178 15.84 13.0606C14.2094 12.9781 12.6144 12.5536 11.1587 11.8145C9.70287 11.0754 8.41885 10.0383 7.39 8.7706C7.02914 9.40077 6.83952 10.1144 6.84 10.8406C6.83872 11.515 7.00422 12.1792 7.32176 12.7742C7.63929 13.3691 8.09902 13.8763 8.66 14.2506C8.00798 14.2329 7.36989 14.0579 6.8 13.7406V13.7906C6.80489 14.7355 7.13599 15.6497 7.73731 16.3786C8.33864 17.1074 9.17326 17.6062 10.1 17.7906C9.74326 17.8992 9.37288 17.9564 9 17.9606C8.74189 17.9576 8.48442 17.9342 8.23 17.8906C8.49391 18.7034 9.00462 19.4137 9.69107 19.9228C10.3775 20.4318 11.2056 20.7142 12.06 20.7306C10.6172 21.8659 8.83588 22.4855 7 22.4906C6.66574 22.4917 6.33174 22.4717 6 22.4306C7.87443 23.6409 10.0588 24.2833 12.29 24.2806C13.8297 24.2966 15.3571 24.0056 16.7831 23.4247C18.2091 22.8437 19.505 21.9845 20.5952 20.8971C21.6854 19.8097 22.548 18.516 23.1326 17.0915C23.7172 15.667 24.012 14.1403 24 12.6006C24 12.4306 24 12.2506 24 12.0706C24.7847 11.4854 25.4615 10.768 26 9.9506Z\"\/>\n  <\/g>\n  <g id=\"linkedin\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M10.4092 25.75H6.08646V13.1473H10.4092V25.75ZM8.24784 11.3829C7.65167 11.3829 7.07993 11.1528 6.65838 10.7431C6.23682 10.3335 6 9.77783 6 9.19847C6 8.61911 6.23682 8.06349 6.65838 7.65382C7.07993 7.24415 7.65167 7.014 8.24784 7.014C8.5644 6.97911 8.88498 7.0096 9.18858 7.10346C9.49218 7.19732 9.77196 7.35244 10.0096 7.55867C10.2472 7.76489 10.4374 8.01757 10.5675 8.30015C10.6977 8.58274 10.765 8.88886 10.765 9.19847C10.765 9.50808 10.6977 9.8142 10.5675 10.0968C10.4374 10.3794 10.2472 10.632 10.0096 10.8383C9.77196 11.0445 9.49218 11.1996 9.18858 11.2935C8.88498 11.3873 8.5644 11.4178 8.24784 11.3829ZM26 25.75H21.6772V18.9866C21.6772 17.2922 21.0576 16.186 19.487 16.186C19.001 16.1894 18.5276 16.3376 18.1309 16.6105C17.7341 16.8834 17.433 17.2679 17.268 17.7123C17.1553 18.0414 17.1064 18.388 17.1239 18.7345V25.736H12.8012C12.8012 25.736 12.8012 14.2816 12.8012 13.1333H17.1239V14.9117C17.5166 14.2495 18.0878 13.704 18.7759 13.3338C19.4639 12.9637 20.2429 12.783 21.0288 12.8112C23.9107 12.8112 26 14.6176 26 18.4965V25.75Z\"\/>\n  <\/g>\n  <g id=\"share\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M21.4994 23.9007H8.47991V10.9629H11.8416C12.6131 9.96349 13.5086 9.14204 14.5419 8.49857H7.9977C6.89552 8.49857 6 9.38848 6 10.4837V24.3799C6 25.4752 6.89552 26.3651 7.9977 26.3651H21.9816C23.0838 26.3651 23.9793 25.4752 23.9793 24.3799V14.2898L21.4994 16.1175V23.9007Z\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M10.0574 22.2921C12.9437 14.4472 17.4696 12.8249 19.7704 12.5305V15.8574L26.4524 10.9287L19.7704 6V8.10154C9.04478 9.01198 10.0574 22.2921 10.0574 22.2921Z\"\/>\n  <\/g>\n  <g id=\"youtube\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M16.0644 9H16.1756C17.2032 9.00375 22.4098 9.04125 23.8136 9.41878C24.238 9.53399 24.6247 9.75858 24.9351 10.0701C25.2455 10.3816 25.4688 10.7691 25.5825 11.1939C25.7087 11.6689 25.7975 12.2977 25.8575 12.9465L25.87 13.0765L25.8975 13.4015L25.9075 13.5315C25.9888 14.6741 25.9988 15.7442 26 15.9779V16.0717C25.9988 16.3142 25.9875 17.4568 25.8975 18.6469L25.8875 18.7781L25.8762 18.9081C25.8137 19.6232 25.7212 20.3332 25.5825 20.8557C25.4691 21.2807 25.246 21.6684 24.9355 21.98C24.6251 22.2915 24.2382 22.516 23.8136 22.6309C22.3635 23.0209 16.8519 23.0484 16.0881 23.0496H15.9106C15.5243 23.0496 13.9267 23.0421 12.2516 22.9846L12.0391 22.9771L11.9304 22.9721L11.7166 22.9634L11.5028 22.9546C10.1153 22.8934 8.79392 22.7946 8.18514 22.6296C7.76072 22.5148 7.37392 22.2906 7.06347 21.9792C6.75303 21.6679 6.52984 21.2805 6.41628 20.8557C6.27752 20.3345 6.18501 19.6232 6.12251 18.9081L6.11251 18.7769L6.10251 18.6469C6.04081 17.7998 6.00663 16.951 6 16.1017L6 15.9479C6.0025 15.6792 6.0125 14.7504 6.08001 13.7253L6.08876 13.5965L6.09251 13.5315L6.10251 13.4015L6.13001 13.0765L6.14251 12.9465C6.20251 12.2977 6.29127 11.6677 6.41753 11.1939C6.5309 10.7689 6.754 10.3812 7.06446 10.0697C7.37492 9.75811 7.76182 9.53365 8.18639 9.41878C8.79517 9.25627 10.1165 9.15626 11.5041 9.09376L11.7166 9.08501L11.9316 9.07751L12.0391 9.07375L12.2529 9.065C13.4426 9.02672 14.6328 9.00547 15.8231 9.00125H16.0644V9ZM14.0005 13.0128V19.0356L19.1971 16.0254L14.0005 13.0128Z\"\/>\n  <\/g>\n  <g id=\"instagram\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M21.34 9.46C21.1027 9.46 20.8707 9.53038 20.6733 9.66224C20.476 9.79409 20.3222 9.98151 20.2313 10.2008C20.1405 10.4201 20.1168 10.6613 20.1631 10.8941C20.2094 11.1269 20.3236 11.3407 20.4915 11.5085C20.6593 11.6764 20.8731 11.7906 21.1059 11.8369C21.3387 11.8832 21.5799 11.8595 21.7992 11.7687C22.0185 11.6778 22.2059 11.524 22.3378 11.3267C22.4696 11.1293 22.54 10.8973 22.54 10.66C22.54 10.3417 22.4136 10.0365 22.1885 9.81147C21.9635 9.58643 21.6583 9.46 21.34 9.46ZM25.94 11.88C25.9206 11.0503 25.7652 10.2294 25.48 9.45C25.2257 8.78313 24.83 8.17928 24.32 7.68C23.8248 7.16743 23.2196 6.77418 22.55 6.53C21.7727 6.23616 20.9508 6.07721 20.12 6.06C19.06 6 18.72 6 16 6C13.28 6 12.94 6 11.88 6.06C11.0492 6.07721 10.2273 6.23616 9.45 6.53C8.78168 6.77665 8.17693 7.16956 7.68 7.68C7.16743 8.17518 6.77418 8.78044 6.53 9.45C6.23616 10.2273 6.07721 11.0492 6.06 11.88C6 12.94 6 13.28 6 16C6 18.72 6 19.06 6.06 20.12C6.07721 20.9508 6.23616 21.7727 6.53 22.55C6.77418 23.2196 7.16743 23.8248 7.68 24.32C8.17693 24.8304 8.78168 25.2234 9.45 25.47C10.2273 25.7638 11.0492 25.9228 11.88 25.94C12.94 26 13.28 26 16 26C18.72 26 19.06 26 20.12 25.94C20.9508 25.9228 21.7727 25.7638 22.55 25.47C23.2196 25.2258 23.8248 24.8326 24.32 24.32C24.8322 23.8226 25.2283 23.2182 25.48 22.55C25.7652 21.7706 25.9206 20.9497 25.94 20.12C25.94 19.06 26 18.72 26 16C26 13.28 26 12.94 25.94 11.88ZM24.14 20C24.1327 20.6348 24.0178 21.2637 23.8 21.86C23.6403 22.2952 23.3839 22.6884 23.05 23.01C22.7256 23.3405 22.3332 23.5964 21.9 23.76C21.3037 23.9778 20.6748 24.0927 20.04 24.1C19.04 24.15 18.67 24.16 16.04 24.16C13.41 24.16 13.04 24.16 12.04 24.1C11.3809 24.1123 10.7246 24.0109 10.1 23.8C9.68578 23.6281 9.31136 23.3728 9 23.05C8.66809 22.7287 8.41484 22.3352 8.26 21.9C8.01586 21.2952 7.88044 20.6519 7.86 20C7.86 19 7.8 18.63 7.8 16C7.8 13.37 7.8 13 7.86 12C7.86448 11.3511 7.98295 10.7079 8.21 10.1C8.38605 9.67791 8.65626 9.30166 9 9C9.30381 8.65617 9.67929 8.3831 10.1 8.2C10.7096 7.98004 11.352 7.86508 12 7.86C13 7.86 13.37 7.8 16 7.8C18.63 7.8 19 7.8 20 7.86C20.6348 7.86728 21.2637 7.98225 21.86 8.2C22.3144 8.36865 22.7223 8.64285 23.05 9C23.3777 9.30718 23.6338 9.68273 23.8 10.1C24.0223 10.7089 24.1373 11.3518 24.14 12C24.19 13 24.2 13.37 24.2 16C24.2 18.63 24.19 19 24.14 20ZM16 10.87C14.9858 10.872 13.995 11.1745 13.1527 11.7394C12.3103 12.3043 11.6544 13.1062 11.2676 14.0438C10.8809 14.9813 10.7807 16.0125 10.9798 17.0069C11.1789 18.0014 11.6682 18.9145 12.3861 19.631C13.1039 20.3474 14.018 20.835 15.0129 21.0321C16.0077 21.2293 17.0387 21.1271 17.9755 20.7385C18.9123 20.35 19.7129 19.6924 20.2761 18.849C20.8394 18.0056 21.14 17.0142 21.14 16C21.1413 15.3251 21.0092 14.6566 20.7512 14.033C20.4933 13.4093 20.1146 12.8428 19.6369 12.3661C19.1592 11.8893 18.5919 11.5117 17.9678 11.2549C17.3436 10.9982 16.6749 10.8674 16 10.87ZM16 19.33C15.3414 19.33 14.6976 19.1347 14.15 18.7688C13.6023 18.4029 13.1755 17.8828 12.9235 17.2743C12.6714 16.6659 12.6055 15.9963 12.734 15.3503C12.8625 14.7044 13.1796 14.111 13.6453 13.6453C14.111 13.1796 14.7044 12.8625 15.3503 12.734C15.9963 12.6055 16.6659 12.6714 17.2743 12.9235C17.8828 13.1755 18.4029 13.6023 18.7688 14.15C19.1347 14.6976 19.33 15.3414 19.33 16C19.33 16.4373 19.2439 16.8703 19.0765 17.2743C18.9092 17.6784 18.6639 18.0454 18.3547 18.3547C18.0454 18.6639 17.6784 18.9092 17.2743 19.0765C16.8703 19.2439 16.4373 19.33 16 19.33Z\"\/>\n  <\/g>\n<\/svg>\t\t\t\t\t\t\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do you know: Can you take cyclobenzaprine with tramadol? in 2025 Key takeaways Cyclobenzaprine is a muscle relaxer prescribed primarily to treat spasms, while tramadol is an opioid used for short-term acute pain relief.\u00a0 Both drugs act on the central nervous system, and together, they may cause CNS depression\u2014a condition that could cause a range [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7034","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7034","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=7034"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7034\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=7034"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=7034"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=7034"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}