{"id":7557,"date":"2025-06-08T22:05:50","date_gmt":"2025-06-08T22:05:50","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-take-cyclobenzaprine-while-pregnant-what-to-know-in-2025\/"},"modified":"2025-06-08T22:05:50","modified_gmt":"2025-06-08T22:05:50","slug":"hmn-can-you-take-cyclobenzaprine-while-pregnant-what-to-know-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-take-cyclobenzaprine-while-pregnant-what-to-know-in-2025\/","title":{"rendered":"HMN: Can you take cyclobenzaprine while pregnant? What to know in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Can you take cyclobenzaprine while pregnant? What to know in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">It is generally considered safe to take cyclobenzaprine during the second and third trimesters of pregnancy.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">There is little research on cyclobenzaprine use during pregnancy, but the main risk of the medication seems to be sedation.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Speak with your healthcare provider to determine if taking a muscle relaxant medication while pregnant is right for you.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div tabindex=\"0\" class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine<\/span><span style=\"font-weight: 400;\"> is a prescription medication used to treat muscle spasms, stiffness, and pain. It is in a class of medications called skeletal muscle relaxants. Brand names include <\/span><span style=\"font-weight: 400;\">Amrix<\/span><span style=\"font-weight: 400;\"> (an extended-release version of the drug that is taken once per day), <\/span><span style=\"font-weight: 400;\">Fexmid<\/span><span style=\"font-weight: 400;\">, and Flexeril (taken up to three times per day). In general, it is considered safe to use cyclobenzaprine during the second and third trimesters of pregnancy.<\/span><\/p>\n<h2 id=\"can-you-take-cyclobenzaprine-while-pregnant\"><span style=\"font-weight: 400;\">Can you take cyclobenzaprine while pregnant?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Typically, a woman would be prescribed cyclobenzaprine during pregnancy because of a muscle spasm, explains <\/span><span style=\"font-weight: 400;\">Kecia Gaither, MD, the\u00a0 Director of Perinatal Services\/Maternal Fetal Medicine at NYC Health + Hospitals\/Lincoln in the Bronx in New York City.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine is considered a category B medication by the FDA, which means that animal studies have not shown any adverse effects. <\/span><span style=\"font-weight: 400;\">It is generally considered safe to take cyclobenzaprine during pregnancy. There is very little human research on taking this drug during pregnancy. However, the consensus in the medical community is that it\u2019s okay to take during the second and third trimesters (weeks 14 to 40 of pregnancy). Caution is important for all medications taken in the first trimester (0 to 13 weeks of pregnancy) when a baby\u2019s organ systems are forming because there are no safety data available for the use of cyclobenzaprine in humans during the first trimester.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, there is also concern about taking the medication during the last three months of pregnancy because \u201c<\/span><span style=\"font-weight: 400;\">cyclobenzaprine produces drowsiness as a side effect, so the use of it in the third trimester may cause drowsiness in the newborn,\u201d said <\/span><a href=\"https:\/\/keciagaither.com\/\"><span style=\"font-weight: 400;\">Dr. Gaither<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In fact, this medication can be a safe alternative to other pain relievers for muscle spasms during pregnancy. \u201cWe find it works very well for people with some kind of musculoskeletal issue requiring relaxation,\u201d explains <\/span><a href=\"https:\/\/mdmercy.com\/find-a-doctor\/robert-atlas-md\"><span style=\"font-weight: 400;\">Robert Atlas<\/span><\/a><span style=\"font-weight: 400;\">, MD, chair of the Department of Obstetrics and Gynecology at Mercy Medical Center in Baltimore, Maryland. \u201cAs much as we might like to use a nonsteroidal anti-inflammatory drug like Motrin during pregnancy, you\u2019re generally not supposed to.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s important to understand that cyclobenzaprine should only be used if needed and only as a short-term medication \u201cIt could be used for a couple of days up to a week or so,\u201d says Dr. Atlas. \u201cThis isn\u2019t something we\u2019d use long-term, but something to help relieve pain in the short term.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Plus, if you are planning on nursing, this medication is safe for breastfeeding. The amount of medication that transfers into human milk appears to be very small, according to a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31017819\/\"><span style=\"font-weight: 400;\">case report<\/span><\/a><span style=\"font-weight: 400;\"> in the <\/span><i><span style=\"font-weight: 400;\">Journal of Human Lactation<\/span><\/i><span style=\"font-weight: 400;\">, and does not constitute a risk to a breastfed infant. Still, because the medication is a sedative, it is key to monitor your baby closely if you are taking cyclobenzaprine while breastfeeding.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine coupons<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">Amrix coupons<\/span><\/p>\n<h2 id=\"what-are-the-risks-of-taking-cyclobenzaprine-while-pregnant\"><span style=\"font-weight: 400;\">What are the risks of taking cyclobenzaprine while pregnant?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because there is limited data on humans taking cyclobenzaprine while pregnant, it is difficult to identify all of the possible risks. Here\u2019s what we know.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">One <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36942828\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> found increased odds of congenital disorders with the use of cyclobenzaprine during the time before conception and the first trimester. Still, the authors note that the results should be interpreted with caution, and more studies need to be done. Cyclobenzaprine does cross the placenta, which means that the fetus will be exposed to the medication along with the mother.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">General side effects of cyclobenzaprine include drowsiness, dizziness, constipation, and dry mouth. It may also increase your heart rate or cause an irregular heartbeat (arrhythmia). If you experience chest pain or changes in your heart rate while taking cyclobenzaprine, stop taking it right away and contact a healthcare provider.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cyclobenzaprine is part of a class of medications called <\/span><span style=\"font-weight: 400;\">cyclic antidepressants<\/span><span style=\"font-weight: 400;\">. It is considered a <\/span><span style=\"font-weight: 400;\">tricyclic amine salt, and it works in the central nervous system as a depressant by reducing muscle hyperactivity (otherwise known as muscle spasms). Because of this, a few kinds of medications do not mix with cyclobenzaprine:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While many of these medications are not recommended during pregnancy, it is recommended to avoid combining them with cyclobenzaprine because of the risk of serious side effects. Certain <\/span><span style=\"font-weight: 400;\">combinations of drugs <\/span><span style=\"font-weight: 400;\">can cause a condition called <\/span><span style=\"font-weight: 400;\">serotonin syndrome<\/span><span style=\"font-weight: 400;\">, which happens when there is a buildup of serotonin in your brain. It can be life-threatening and cause <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3669814\/\"><span style=\"font-weight: 400;\">psychiatric problems<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should not take cyclobenzaprine if you have a history of:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hyperthyroidism<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Myocardial infarction (heart attack)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Arrhythmias (irregular heartbeat)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart block or conduction disturbance<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary retention<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you do take cyclobenzaprine while pregnant, it is important to monitor yourself closely for side effects. The biggest side effect to watch for during pregnancy is drowsiness. Dr. Atlas says cyclobenzaprine is\u00a0 \u201cdefinitely sedating, so patients need to be careful about ambulation while on it\u2014especially during pregnancy since balance can already be a challenge at that time.\u201d<\/span><\/p>\n<h2 id=\"what-can-i-take-instead-of-cyclobenzaprine-during-pregnancy\"><span style=\"font-weight: 400;\">What can I take instead of cyclobenzaprine during pregnancy?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Despite the lack of research, <\/span><span style=\"font-weight: 400;\">cyclobenzaprine<\/span><span style=\"font-weight: 400;\"> is generally considered the safest muscle relaxant to use during pregnancy. This is because it has been used in practice with pregnant people for years. While there are other options (such as <\/span><span style=\"font-weight: 400;\">carisoprodol<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">metaxalone<\/span><span style=\"font-weight: 400;\">, and<\/span> <span style=\"font-weight: 400;\">tizanidine<\/span><span style=\"font-weight: 400;\">), alternative medications that work to relax muscles have even less research on their effects on pregnant people and babies.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The muscle relaxant that is best to take while pregnant will depend on your situation. You should discuss your options with your healthcare provider to determine which medication is right for you.<\/span><\/p>\n<h2 id=\"natural-remedies-for-muscle-spasms-during-pregnancy\"><span style=\"font-weight: 400;\">Natural remedies for muscle spasms during pregnancy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Whether you choose to take cyclobenzaprine or not, other therapies, treatments, and remedies can be helpful if you experience muscle spasms during pregnancy. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Massage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acupuncture<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acupressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Epsom salt baths<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Applying heat or ice to the affected area<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Topical creams<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Physical therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stretching<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Dr. Atlas advises, \u201cAcupressure or acupuncture is very useful and safe in pregnancy. Warm baths can also be relaxing as long as the temperature isn\u2019t too high, especially in the first trimester. At term, a bath at around 100\u00b0F is fine and can be helpful.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It is unclear if taking vitamins or supplements is useful to help treat muscle spasms during pregnancy. While some people seem to find relief with magnesium supplementation to help with leg cramps (a type of muscle spasm) during pregnancy, a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31923242\/\"><span style=\"font-weight: 400;\">study<\/span><\/a> <span style=\"font-weight: 400;\">did not find a reduction in the frequency and occurrence of leg cramps when women took oral magnesium.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Be sure to communicate with your provider or midwife if you are experiencing pain and need relief. Together, you can determine a plan to help your muscle spasms and ensure you feel better. It may make sense to use a combination of therapies, such as an over-the-counter (OTC) medication like acetaminophen, along with home remedies. If these therapies don\u2019t give you relief from your muscle pain or spasm, work with your provider to determine if a muscle relaxant is right for you.<\/span><\/p>\n<p><svg style=\"display:none\">\n  <g id=\"facebook\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M19.51 9.32003H21.39V6.14003C20.4798 6.04538 19.5652 5.99865 18.65 6.00003C15.93 6.00003 14.07 7.66003 14.07 10.7V13.32H11V16.88H14.07V26H17.75V16.88H20.81L21.27 13.32H17.75V11.05C17.75 10 18.03 9.32003 19.51 9.32003Z\"\/>\n  <\/g>\n  <g id=\"twitter\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M26 9.9506C25.2483 10.2767 24.4534 10.4923 23.64 10.5906C24.4982 10.0779 25.1413 9.27138 25.45 8.3206C24.6436 8.80066 23.7608 9.1389 22.84 9.3206C22.2245 8.65317 21.405 8.2089 20.5098 8.05745C19.6147 7.90601 18.6945 8.05596 17.8938 8.48379C17.093 8.91162 16.4569 9.59313 16.0852 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What to know in 2025 Key takeaways It is generally considered safe to take cyclobenzaprine during the second and third trimesters of pregnancy. There is little research on cyclobenzaprine use during pregnancy, but the main risk of the medication seems to be sedation. Speak with your [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7557","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=7557"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7557\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=7557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=7557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=7557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}