{"id":7604,"date":"2025-06-15T11:02:13","date_gmt":"2025-06-15T11:02:13","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-switch-from-armour-thyroid-to-levothyroxine-in-2025\/"},"modified":"2025-06-15T11:02:13","modified_gmt":"2025-06-15T11:02:13","slug":"hmn-can-you-switch-from-armour-thyroid-to-levothyroxine-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-can-you-switch-from-armour-thyroid-to-levothyroxine-in-2025\/","title":{"rendered":"HMN: Can you switch from Armour Thyroid to levothyroxine? in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Can you switch from Armour Thyroid to levothyroxine? in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Armour Thyroid and levothyroxine are both thyroid hormone drugs that are used in the treatment of hypothyroidism, an underactive thyroid state.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Armour Thyroid consists of two thyroid hormone forms, triiodothyronine and thyroxine, and is derived from desiccated pig thyroids, whereas levothyroxine consists of synthetic thyroxine.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Levothyroxine is approved by the Food and Drug Administration and preferred over desiccated thyroid extracts in hypothyroidism care guidelines.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Product consistency could be better with levothyroxine, and its price may be lower than Armour Thyroid.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Converting from Armour Thyroid to levothyroxine can be done under the guidance of a healthcare provider who can recommend an appropriate dose and monitor its effectiveness with blood tests.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div tabindex=\"0\" class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Effective treatment of an underactive thyroid gland can increase energy levels and help with healthy weight maintenance. Treatment options involve taking supplemental <\/span><span style=\"font-weight: 400;\">thyroid hormone<\/span><span style=\"font-weight: 400;\">, which may include <\/span><span style=\"font-weight: 400;\">Armour Thyroid<\/span><span style=\"font-weight: 400;\"> or generic and brand-name <\/span><span style=\"font-weight: 400;\">levothyroxine<\/span><span style=\"font-weight: 400;\"> products. Based on medical expert recommendations and product consistency, people may want to switch from Armour Thyroid to levothyroxine. This request is reasonable and can be done safely under the supervision of a healthcare provider. We\u2019ll cover how and why people make this change in hypothyroidism treatment.<\/span><\/p>\n<h2 id=\"what-are-the-benefits-of-switching-from-armour-thyroid-to-levothyroxine-for-hypothyroidism\"><span style=\"font-weight: 400;\">What are the benefits of switching from Armour Thyroid to levothyroxine for hypothyroidism?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Armour Thyroid<\/span><span style=\"font-weight: 400;\"> is derived from desiccated pig thyroids and contains both thyroxine (T4) and triiodothyronine (T3) forms of thyroid hormone. In comparison, <\/span><span style=\"font-weight: 400;\">levothyroxine sodium<\/span><span style=\"font-weight: 400;\"> is a synthetic product containing only T4, but since the human body converts T4 to T3 naturally, levothyroxine products ultimately result in higher levels of both forms of thyroid hormone. <\/span><span style=\"font-weight: 400;\">Changing from Armour Thyroid<\/span><span style=\"font-weight: 400;\"> to levothyroxine might be worthwhile from a few standpoints.<\/span><\/p>\n<h3 id=\"expert-guidelines\"><span style=\"font-weight: 400;\">Expert guidelines<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/thy.2014.0028\"><span style=\"font-weight: 400;\">American Thyroid Association (ATA) recommends levothyroxine<\/span><\/a><span style=\"font-weight: 400;\"> over desiccated thyroid products for the treatment of hypothyroidism. Based on this expert guideline, many doctors and hypothyroid patients prefer levothyroxine over Armour Thyroid.<\/span><\/p>\n<h3 id=\"product-consistency\"><span style=\"font-weight: 400;\">Product consistency<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Using dried porcine thyroid glands to produce the drug may not result in consistent levels of T4 and T3 in Armour Thyroid, <\/span><a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/older-therapies-arent-necessarily-better-thyroid-hormone-replacement\"><span style=\"font-weight: 400;\">according to the FDA<\/span><\/a><span style=\"font-weight: 400;\">. The FDA has not approved Armour Thyroid or a similar product, <\/span><span style=\"font-weight: 400;\">NP Thyroid<\/span><span style=\"font-weight: 400;\">. The fear is that if levels of T4 and T3 fluctuate from pill to pill, then adverse effects or suboptimal control of hypothyroidism could result.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23539727\/\"><span style=\"font-weight: 400;\">small study<\/span><\/a><span style=\"font-weight: 400;\"> of 70 patients showed similar outcomes, more weight loss, and better patient satisfaction with desiccated thyroid extract (DTE) than levothyroxine, meaning that it may have a treatment role in some situations, but further studies are needed. Nonetheless, the FDA has specifically placed a warning on the labels of <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=56b41079-60db-4256-9695-202b3a65d13d\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=a6233381-3043-4e9a-aaa6-a6b105e5142b\"><span style=\"font-weight: 400;\">levothyroxine<\/span><\/a><span style=\"font-weight: 400;\"> stating that thyroid hormone products should not be used for weight loss, particularly among people who are euthyroid (have normal thyroid function) because of the dangers of excess thyroid hormone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Levothyroxine products are FDA approved and standardized. In fact, no significant differences were found between <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8886450\/\"><span style=\"font-weight: 400;\">patients in a study who changed their levothyroxine manufacturer<\/span><\/a><span style=\"font-weight: 400;\"> and those who did not, even among different manufacturers of generic products. This finding supports the notion that sticking with certain brand-name levothyroxine products, like <\/span><span style=\"font-weight: 400;\">Synthroid<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">Levoxyl<\/span><span style=\"font-weight: 400;\">, or <\/span><span style=\"font-weight: 400;\">Unithroid<\/span><span style=\"font-weight: 400;\">, over generic alternatives for reasons of consistency is not always necessary. Based on the perceived consistency among levothyroxine products, endocrinologists tend to favor it over desiccate thyroid extracts like Armour Thyroid.<\/span><\/p>\n<h3 id=\"adverse-effects-of-desiccated-thyroid-products\"><span style=\"font-weight: 400;\">Adverse effects of desiccated thyroid products<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Overtreatment of hypothyroidism entails risk. Too much thyroid hormone can lead to problems like tachycardia, which is an excessively high heart rate that can, in turn, prompt heart arrhythmias or heart attacks among those who are susceptible. A lack of standardization of desiccated thyroid products by the Food and Drug Administration (FDA) was called into question in <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28225316\/\"><span style=\"font-weight: 400;\">a study looking at the adverse effects of thyroid hormone extracts<\/span><\/a><span style=\"font-weight: 400;\"> like Armour Thyroid.\u00a0<\/span><\/p>\n<h3 id=\"cost-savings\"><span style=\"font-weight: 400;\">Cost savings<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Generic levothyroxine can be cheaper than Armour Thyroid, particularly when a <\/span><span style=\"font-weight: 400;\"> discount card<\/span><span style=\"font-weight: 400;\"> is used. With a <\/span><span style=\"font-weight: 400;\"> coupon for Armour Thyroid<\/span><span style=\"font-weight: 400;\">, you may pay about $29 for 30, 60 mg tablets. In contrast, levothyroxine costs about $3 for 30, 75 mcg tablets with a <\/span><span style=\"font-weight: 400;\"> coupon<\/span><span style=\"font-weight: 400;\">. Keep in mind that prices will vary among the <\/span><span style=\"font-weight: 400;\">over 35,000 pharmacies that accept the  prescription discount card<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"armour-thyroid-vs-levothyroxine-comparison-chart\"><span class=\"title\">Armour Thyroid vs. levothyroxine comparison chart<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Usual dose and frequency<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">60\u2013120 mg once daily<\/span><\/td>\n<td><span style=\"font-weight: 400;\">50\u2013200 mcg once daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>Brand or generic<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">Brand product only<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic products<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>Active ingredients<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">T4 and T3<\/span><\/td>\n<td><span style=\"font-weight: 400;\">T4<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>Source of hormone<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">Desiccated pig thyroids<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Synthetic form<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>Administration guidelines<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">Taken on an empty stomach 30\u201360 minutes before breakfast<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Taken on an empty stomach 30\u201360 minutes before breakfast<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>FDA approval for hypothyroidism<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>ATA recommended<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong>Retail cost*<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">$56 for 30, 60 mg tablets of brand-name Armour Thyroid<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$22 for 30, 75 mcg tablets of generic levothyroxine<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong> cost*<\/strong><\/td>\n<td><span style=\"font-weight: 400;\">$29 for 30, 60 mg tablets of brand-name Armour Thyroid<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$3 for 30, 75 mcg tablets of generic levothyroxine<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><span style=\"font-weight: 400;\">*Cost at time of publication. Drug prices fluctuate and vary by location and pharmacy.<\/span><\/h5>\n<h2 id=\"how-to-switch-from-armour-thyroid-to-levothyroxine\"><span style=\"font-weight: 400;\">How to switch from Armour Thyroid to levothyroxine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Changing from Armour Thyroid to levothyroxine can be done, but only with the guidance of a healthcare professional. Under their direction, you can typically stop taking Armour Thyroid and replace it with levothyroxine immediately.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finding an equivalent dose requires your healthcare provider to do a conversion. Armour Thyroid\u2019s label states that 1 grain of DTE, or 60 mg, contains 38 mcg of T4 and 9 mcg of T3. Based on the body converting T3 to T4 and T3 being more metabolically active than T4, 60 mg of DTE should provide about 74 mcg of effective T4.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8530721\/\"><span style=\"font-weight: 400;\">Comparison studies<\/span><\/a><span style=\"font-weight: 400;\"> have used 88 to 100 mcg of levothyroxine as a rough equivalent to 60 mg of Armour Thyroid. If the prescribing provider uses this conversion and the patient is taking Armour Thyroid 60 mg, they may have the patient change to levothyroxine 88 mcg.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Regardless of the thyroid preparation you choose to use, it is crucial to take your medication as directed. Armour Thyroid and levothyroxine tablets should be taken on an empty stomach, 30\u201360 minutes before breakfast. They both interact with similar medications: Neither of them should be taken with calcium, magnesium, iron, or antacid products since they can reduce the absorption of thyroid hormone products.<\/span><\/p>\n<h2 id=\"side-effects-from-stopping-armour-thyroid-and-starting-levothyroxine\"><span style=\"font-weight: 400;\">Side effects from stopping Armour Thyroid and starting levothyroxine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When changing from Armour Thyroid to levothyroxine, the transition may not always be a smooth one. If the healthcare provider overestimates the conversion, the patient could get too much thyroxine and experience symptoms of hyperthyroidism, such as shakiness, palpitations, and diarrhea. The opposite could occur in cases where the patient takes too low of a dose of levothyroxine to replace Armour Thyroid. Examples include constipation, fatigue, and intolerance of cold temperatures.<\/span><\/p>\n<h3 id=\"how-to-minimize-levothyroxine-side-effects\"><span style=\"font-weight: 400;\">How to minimize levothyroxine side effects\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Close monitoring is the key to reducing the risk of levothyroxine side effects when switching from Armour Thyroid. Healthcare providers will prescribe a dose of levothyroxine that is estimated to be equivalent to the current Armour Thyroid dose. <\/span><span style=\"font-weight: 400;\">Blood tests that examine the level of thyroid stimulating hormone (TSH)<\/span><span style=\"font-weight: 400;\"> are then done periodically to assess whether the dose results in a normal thyroid hormone level in the body. Oftentimes, TSH is checked four to six weeks after a medication change and then less often once a given dose is proven effective.<\/span><\/p>\n<h2 id=\"signs-your-thyroid-medication-is-working\"><span style=\"font-weight: 400;\">Signs your thyroid medication is working<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Symptoms of hypothyroidism<\/span><span style=\"font-weight: 400;\"> should dissipate when thyroid hormone replacement is adequate. Ideally, that means energy levels, temperature regulation, bowel habits, weight, skin moisture, and menstruation will all be normalized, assuming an underactive thyroid was to blame. In reality, though, issues with these elements of our health can come from other problems besides hypothyroidism.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Similarly, you can tell your thyroid medication is working and that you\u2019re taking the right dose if your <\/span><span style=\"font-weight: 400;\">hyperthyroid<\/span><span style=\"font-weight: 400;\"> symptoms diminish. Examples include tremor, palpitations, heat intolerance, anxiety, weight loss, and diarrhea.<\/span><\/p>\n<h2 id=\"indicators-of-abnormal-thyroxine-levels\"><span style=\"font-weight: 400;\">Indicators of abnormal thyroxine levels<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If your <\/span><span style=\"font-weight: 400;\">TSH levels<\/span><span style=\"font-weight: 400;\"> are too low or too high, your healthcare provider will need to adjust your dosage. For example, low <\/span><span style=\"font-weight: 400;\">TSH levels can indicate that thyroxine levels are too high, meaning that the levothyroxine dose needs to be reduced. Dosing and targeted TSH values may be different in cases of Hashimoto\u2019s thyroiditis-induced hypothyroidism compared to hypothyroidism after thyroid removal for thyroid cancer.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Conversely, high TSH levels suggest that thyroxine levels are low, which makes the pituitary gland produce more TSH. In that case, the levothyroxine dose may need to be increased. Your primary care provider or endocrinologist will help interpret your symptoms and lab results in order to make a dosing decision.<\/span><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Switching from Armour Thyroid to levothyroxine may be beneficial for some patients, but not all. If recommended by your healthcare provider, they will need to guide you through the change and monitor its effectiveness afterward. Proper treatment of hypothyroidism can make a world of difference for patients, even if it involves trying different medications.\u00a0<\/span><\/p>\n<p><svg style=\"display:none\">\n  <g id=\"facebook\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M19.51 9.32003H21.39V6.14003C20.4798 6.04538 19.5652 5.99865 18.65 6.00003C15.93 6.00003 14.07 7.66003 14.07 10.7V13.32H11V16.88H14.07V26H17.75V16.88H20.81L21.27 13.32H17.75V11.05C17.75 10 18.03 9.32003 19.51 9.32003Z\"\/>\n  <\/g>\n  <g id=\"twitter\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M26 9.9506C25.2483 10.2767 24.4534 10.4923 23.64 10.5906C24.4982 10.0779 25.1413 9.27138 25.45 8.3206C24.6436 8.80066 23.7608 9.1389 22.84 9.3206C22.2245 8.65317 21.405 8.2089 20.5098 8.05745C19.6147 7.90601 18.6945 8.05596 17.8938 8.48379C17.093 8.91162 16.4569 9.59313 16.0852 10.4214C15.7135 11.2497 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Armour Thyroid consists of two thyroid hormone forms, triiodothyronine and thyroxine, and is derived from desiccated pig thyroids, whereas [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7604","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=7604"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7604\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=7604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=7604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=7604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}