{"id":7975,"date":"2025-07-28T22:00:03","date_gmt":"2025-07-28T22:00:03","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-aripiprazole-and-alcohol-side-effects-and-risks-in-2025\/"},"modified":"2025-07-28T22:00:03","modified_gmt":"2025-07-28T22:00:03","slug":"hmn-aripiprazole-and-alcohol-side-effects-and-risks-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-aripiprazole-and-alcohol-side-effects-and-risks-in-2025\/","title":{"rendered":"HMN: Aripiprazole and alcohol: Side effects and risks in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Aripiprazole and alcohol: Side effects and risks in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Aripiprazole is a prescription antipsychotic drug used to treat mental health conditions, including bipolar disorder, major depressive disorder, and schizophrenia.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">It is generally not recommended to drink alcohol while taking this medication.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Some may be able to combine aripiprazole with a small amount of alcohol without any issues, while others may experience more serious side effects.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div tabindex=\"0\" class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Aripiprazole<\/span><span style=\"font-weight: 400;\">, also known by the brand name <\/span><span style=\"font-weight: 400;\">Abilify<\/span><span style=\"font-weight: 400;\">, is an atypical antipsychotic medication approved by the Food and Drug Administration (FDA) for the treatment of mental health conditions such as schizophrenia, bipolar I disorder, major depressive disorder, and irritability associated with autism. It has a multifaceted mechanism of action, working by altering how certain natural substances in the brain operate. It is a partial dopamine agonist, which means it helps regulate dopamine receptors in the brain and improve symptoms of schizophrenia and bipolar disorder. Aripiprazole also impacts serotonin receptors, which can improve mood and reduce hallucinations or delusions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Typically, <\/span><span style=\"font-weight: 400;\">aripiprazole<\/span><span style=\"font-weight: 400;\"> is used long-term to manage symptoms. If you used to drink occasionally before starting this prescription drug, you may be wondering if you are able to safely consume alcoholic beverages when taking it. Experts generally do not recommend drinking alcohol while on aripiprazole, though some people may find they are able to drink small amounts of alcohol occasionally without any side effects.<\/span><\/p>\n<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n<p id=\"headline\">Save up to 80% on Aripiprazole with <\/p>\n<p id=\"subheadline\">Different pharmacies offer different prices for the same medication.  helps find the best price for you.<\/p>\n<div class=\"details-wrap\">\n<p>\n\t\t\t\t\tAripiprazole 5 mg (30 Tablets)\t\t\t\t<\/p>\n<p>\n\t\t\t\t\t23663 &#8211; Hampton, VA\t\t\t\t<\/p>\n<\/p><\/div>\n<div class=\"api-response\">\n<div class=\"coupon\">\n<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-food-lion.svg\" alt=\"Food Lion\"\/>\t\t\t<\/div>\n<\/p><\/div>\n<div class=\"coupon\">\n<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-publix.svg\" alt=\"Publix\"\/>\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p>\t\t\tSee Aripiprazole prices at all pharmacies\n\t\t<\/p><\/div>\n<h2 id=\"can-you-drink-while-taking-aripiprazole\"><span style=\"font-weight: 400;\">Can you drink while taking aripiprazole?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cIt\u2019s not generally recommended to drink alcohol while taking aripiprazole,\u201d says Sylvie Stacy, MD, an addiction medicine specialist and chief medical officer of Rehab.com. \u201cDrinking small amounts of alcohol while taking it isn\u2019t necessarily dangerous, but it comes with some risk.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cMixing alcohol with this antipsychotic medication can amplify side effects,\u201d says <\/span><a href=\"https:\/\/www.eleanorhealth.com\/meet-the-team\"><span style=\"font-weight: 400;\">Sherma Morton, MD<\/span><\/a><span style=\"font-weight: 400;\">, national medical director at Eleanor Health. For example, alcohol consumption can add to the sleepiness that some people experience while taking aripiprazole. On top of that, the effects of alcohol are amplified when combined with a drug like aripiprazole, so you may feel more drunk, faster.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Alcohol affects people differently, so for some, a drink here and there won\u2019t pose a problem. However, not everyone can tolerate the combination of alcohol and aripiprazole. \u201cOthers have felt unexpectedly drunk or nauseated after just a drink or two,\u201d <\/span><a href=\"https:\/\/www.rehab.com\/expert\/sylvie-stacy\"><span style=\"font-weight: 400;\">Dr. Stacy<\/span><\/a><span style=\"font-weight: 400;\"> explains. \u201cI have one memorable patient who assumed drinking would be fine in moderation. She ended up confused and emotionally reactive for two days afterward.\u201d\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-632594\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy.png\" alt=\"A chart showing the safety of aripiprazole and alcohol\" width=\"1920\" height=\"900\" srcset=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy.png 1920w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy-300x141.png 300w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy-1024x480.png 1024w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy-768x360.png 768w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/06\/embed_062725_aripiprazole_copy-1536x720.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\"\/><\/p>\n<h2 id=\"what-happens-if-you-mix-aripiprazole-and-alcohol\"><span style=\"font-weight: 400;\">What happens if you mix aripiprazole and alcohol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The combination can intensify the effects of both substances and also undermine the mood stabilizing effects of aripiprazole in the following ways.<\/span><\/p>\n<h3 id=\"increased-side-effects\"><span style=\"font-weight: 400;\">Increased side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">side effects of aripiprazole<\/span><span style=\"font-weight: 400;\"> and of drinking alcohol are quite similar, so combining the two can mean experiencing some side effects at a more intense level.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSide effects of combining aripiprazole and alcohol can be drowsiness, dizziness, and a higher risk of blackouts,\u201d cautions Dr. Stacy. \u201cI\u2019ve heard of patients becoming much more impaired than they expected after just a couple of drinks.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cBoth alcohol and aripiprazole affect your brain and central nervous system,\u201d says Dr. Morton. \u201cWhen combined, they can make you feel more tired, dizzy, or foggy than either would alone. That means your judgment, reaction time, and ability to think clearly can take a hit\u2014which could lead to dangerous situations, especially if you\u2019re driving or need to make quick decisions.\u201d<\/span><\/p>\n<h3 id=\"mood-changes\"><span style=\"font-weight: 400;\">Mood changes<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u201cAbilify affects how the brain processes dopamine and serotonin,\u201d says Dr. Stacy. \u201cAlcohol can influence those effects unpredictably, and it can mess with the stability people are trying to achieve by taking Abilify in the first place.\u201d She further notes that alcohol can worsen agitation, mood swings, and paranoia in people with schizophrenia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Morton notes that combining aripiprazole and alcohol can also lead to additional adverse effects such as confusion, trouble concentrating, mood swings, or worsening anxiety or depression. \u201cFor younger people, the risk of suicidal thoughts may go up,\u201d she says. \u201cAdd alcohol to the mix, and the chances of risky behavior or accidental injury rise significantly.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<\/p>\n<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span><\/p><\/div>\n<p>\t<\/span><\/p>\n<h2 id=\"are-certain-people-at-greater-risk-of-side-effects\"><span style=\"font-weight: 400;\">Are certain people at greater risk of side effects?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While all people taking Abilify and drinking alcohol are at risk of adverse effects, there are certain groups that will be more vulnerable to danger. \u201cSome people are at higher risk from the combo of aripiprazole and alcohol,\u201d says Dr. Morton. They include people with:\u00a0<\/span><\/p>\n<h3 id=\"history-of-alcohol-use-disorder-or-drug-use\"><span style=\"font-weight: 400;\">History of alcohol use disorder or drug use<\/span><\/h3>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11540058\/\"><span style=\"font-weight: 400;\">Decreased impulse control<\/span><\/a><span style=\"font-weight: 400;\"> is a possible adverse effect of Abilify. This means people who have substance use disorders may be at an increased risk of alcohol abuse or consuming drugs while taking this medication, and if they do consume alcohol while taking aripiprazole, they may be more likely to drink too much. \u201cFor people who\u2019ve struggled with substance use in the past, the combination can also increase the chance of relapse or missing doses of their medication,\u201d says Dr. Morton.<\/span><\/p>\n<h3 id=\"dementia-symptoms\"><span style=\"font-weight: 400;\">Dementia symptoms<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Older adults with dementia symptoms are generally advised not to take Abilify, as aripiprazole and other antipsychotics can increase the risk of <\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a603012.html#\"><span style=\"font-weight: 400;\">stroke<\/span><\/a><span style=\"font-weight: 400;\"> for this group. Taking aripiprazole can also increase the chance of death for older people. Consuming this medication along with alcohol, which also increases the chance of stroke, can be potentially deadly.<\/span><\/p>\n<h3 id=\"liver-problems\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The body will need to work harder to process both aripiprazole and alcohol at the same time. If you already have liver problems, this will exacerbate the issue and have possible harmful side effects. \u201cAripiprazole isn\u2019t known to be very toxic to the liver,\u201d says Dr. Stacy. \u201cAlcohol is, though. Really, any psychiatric medication increases the burden to a liver that\u2019s already under stress.\u201d<\/span><\/p>\n<h3 id=\"other-mental-health-prescriptions\"><span style=\"font-weight: 400;\">Other mental health prescriptions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Dr. Stacy says people with mood disorders and psychotic disorders are more likely to experience side effects from mixing Abilify with alcohol. \u201cThey can be more sensitive to changes in mood, cognition, and sedation. Alcohol can worsen all of those things,\u201d says Dr. Stacy. Also, people already taking antidepressants may not be able to take Abilify because of <\/span><span style=\"font-weight: 400;\">how it interacts<\/span><span style=\"font-weight: 400;\"> with their other medications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIf you\u2019re taking other medications that also slow down your nervous system\u2014like sleep aids, opioids, or anti-anxiety meds\u2014the danger is even greater,\u201d says Dr. Morton. Speak with your healthcare provider for medical advice about other medications you are taking before starting Abilify.\u00a0<\/span><\/p>\n<h2 id=\"how-long-after-taking-aripiprazole-can-you-drink-alcohol\"><span style=\"font-weight: 400;\">How long after taking aripiprazole can you drink alcohol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cThis is where things get tricky,\u201d says Dr. Morton. \u201cAripiprazole stays in your system for a long time\u2014up to a week or more after just one dose. That means even a casual drink days later could still interact with the medication. To stay on the safe side, most experts recommend avoiding alcohol entirely while taking aripiprazole.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, if you are going to try having a drink or two while taking aripiprazole, there is not really a certain amount of time you need to wait. \u201cThere\u2019s no specific waiting period because aripiprazole stays in your system for days,\u201d notes Dr. Stacy. \u201cBut if you choose to drink, it\u2019s safest to wait until you\u2019re stable on your dose and know how the medication affects you.\u201d Regardless, Dr. Stacy advises drinking in moderation while taking aripiprazole.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cA single dose can linger in your body for one to two weeks,\u201d reiterates Dr. Morton. \u201cThat means your brain and liver are still dealing with the effects of the drug long after you\u2019ve taken it\u2014so mixing alcohol even days later can still pose risks.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The half-life of aripiprazole is about 75 hours, so it would take about that long for the amount of aripiprazole in your system to be reduced by half. One dose of aripiprazole can stay in the body for as long as a week or more.<\/span><\/p>\n<p><b> <\/b><b>How long does Abilify take to work?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">While taking aripiprazole, it\u2019s a good idea to avoid certain substances aside from alcohol. \u201cAlong with alcohol, it\u2019s smart to steer clear of other substances that can affect your brain, like cannabis, opioids, or certain sleeping pills,\u201d says Dr. Morton. \u201cBe careful when driving or using machinery, especially when you\u2019re still adjusting to the medication. Also, skip the grapefruit juice\u2014it can interfere with how your body processes aripiprazole.\u201d This is because <\/span><span style=\"font-weight: 400;\">grapefruit<\/span><span style=\"font-weight: 400;\"> can make the body process aripiprazole more slowly, causing the drug to build up in the body at higher levels.<\/span><\/p>\n<h2 id=\"which-antipsychotics-are-not-affected-by-alcohol\"><span style=\"font-weight: 400;\">Which antipsychotics are not affected by alcohol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are no antipsychotic drugs that are compatible with alcohol consumption, as the side effects of this class of medication are similar to those of alcohol, which means combining the two can amplify those side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWhile some antipsychotics cause less drowsiness than others, none are completely safe to mix with alcohol,\u201d cautions Dr. Morton. \u201cAripiprazole is actually one of the less sedating options, which is why it\u2019s sometimes used for people with a history of substance use. Still, even in those cases, the recommendation remains the same: it\u2019s best to avoid drinking.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cI wouldn\u2019t recommend choosing a mental health medication based on your preferred drinking patterns,\u201d advises Dr. Stacy. \u201cRather, adjust your drinking to accommodate the medication regimen that best controls your mental health condition.\u201d<\/span><\/p>\n<h2 id=\"the-bottom-line\"><span style=\"font-weight: 400;\">The bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cIf you\u2019re taking aripiprazole\u2014or any antipsychotic\u2014it\u2019s safest to stay away from alcohol,\u201d says Dr. Morton. \u201cThe potential side effects and health risks just aren\u2019t worth it, especially if you have a history of mental health or substance use challenges. Staying sober while on these medications is the best way to protect your health and give the treatment a real chance to work.\u201d<\/span><\/p>\n<p><svg style=\"display:none\">\n  <g id=\"facebook\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M19.51 9.32003H21.39V6.14003C20.4798 6.04538 19.5652 5.99865 18.65 6.00003C15.93 6.00003 14.07 7.66003 14.07 10.7V13.32H11V16.88H14.07V26H17.75V16.88H20.81L21.27 13.32H17.75V11.05C17.75 10 18.03 9.32003 19.51 9.32003Z\"\/>\n  <\/g>\n  <g id=\"twitter\">\n    <rect width=\"32\" height=\"32\" rx=\"4\" fill=\"var(--social-bg)\"\/>\n    <path fill=\"var(--social-ico)\" d=\"M26 9.9506C25.2483 10.2767 24.4534 10.4923 23.64 10.5906C24.4982 10.0779 25.1413 9.27138 25.45 8.3206C24.6436 8.80066 23.7608 9.1389 22.84 9.3206C22.2245 8.65317 21.405 8.2089 20.5098 8.05745C19.6147 7.90601 18.6945 8.05596 17.8938 8.48379C17.093 8.91162 16.4569 9.59313 16.0852 10.4214C15.7135 11.2497 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It is generally not recommended to drink alcohol while taking this medication. Some may be able to combine aripiprazole with a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7975","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7975","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=7975"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/7975\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=7975"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=7975"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=7975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}