{"id":8332,"date":"2025-09-14T17:37:17","date_gmt":"2025-09-14T17:37:17","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-differences-similarities-side-effects-in-2025-39\/"},"modified":"2025-12-23T14:20:27","modified_gmt":"2025-12-23T14:20:27","slug":"hmn-latuda-and-risperidone-differences-similarities-side-effects-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-latuda-and-risperidone-differences-similarities-side-effects-in-2025\/","title":{"rendered":"HMN: Latuda and risperidone Differences, similarities &#038; side effects in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Differences, similarities &#038; side effects in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone are atypical antipsychotics used to treat schizophrenia and bipolar disorder.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Latuda is taken once daily and treats both schizophrenia and bipolar depression, while risperidone can be taken once or twice daily and treats schizophrenia, bipolar mania, and irritability in autism.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Both drugs can cause side effects like drowsiness, weight gain, and movement disorders, but each has unique side effect profiles.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Insurance generally covers both drugs, but Latuda is usually more expensive than risperidone as a brand-name drug.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div tabindex=\"0\" class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p><span style=\"font-weight: 400;\">Latuda<\/span><span style=\"font-weight: 400;\"> (lurasidone) and <\/span><span style=\"font-weight: 400;\">risperidone<\/span><span style=\"font-weight: 400;\"> are two medications often prescribed for conditions like schizophrenia and bipolar disorder. Both belong to a class of drugs known as <\/span><span style=\"font-weight: 400;\">atypical antipsychotics<\/span><span style=\"font-weight: 400;\">. Also called <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK107237\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">second-generation antipsychotic medications<\/span><\/a><span style=\"font-weight: 400;\">, Latuda and risperidone block dopamine receptors and also affect serotonin levels to help manage symptoms such as mood swings, hallucinations, and other psychological disturbances. Second-generation antipsychotics tend to cause fewer side effects and broader therapeutic effects than first-generation antipsychotics.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although they are similarly prescribed medications, Latuda and risperidone have differences in dosages, age restrictions, and potential side effects.\u00a0<\/span><\/p>\n<h2 id=\"latuda-vs-risperidone-key-differences\"><span style=\"font-weight: 400;\">Latuda vs. risperidone: Key differences<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Latuda is a brand-name drug containing the active ingredient lurasidone. The <\/span><span style=\"font-weight: 400;\">generic version of Latuda<\/span><span style=\"font-weight: 400;\"> is widely available. Latuda is typically taken as <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/200603s035lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">one tablet once daily<\/span><\/a><span style=\"font-weight: 400;\">, with oral tablets coming in strengths of 20 milligrams (mg), 40 mg, 60 mg, 80 mg, and 120 mg. The dosage varies depending on the individual and condition being treated.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Risperidone is a generic drug sold under the brand name <\/span><span style=\"font-weight: 400;\">Risperdal<\/span><span style=\"font-weight: 400;\">. Unlike Latuda, risperidone may be taken as one tablet once daily or <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/020272s087,021444s059lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">half a tablet twice daily<\/span><\/a><span style=\"font-weight: 400;\">. Regular oral tablets come in strengths of 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg. Risperidone is also available as an oral solution and an orally disintegrating tablet.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-latuda-vs-risperidone-key-differences\"><span class=\"title\">Compare Latuda vs. risperidone key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Atypical antipsychotic\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Atypical antipsychotic<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic version available<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic version available<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic or brand name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand name: Latuda<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Generic name: Lurasidone<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Brand name: Risperdal, Risperdal Consta, Risperdal M-tabs<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Generic name: Risperidone<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Orally disintegrating tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Oral solution<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Injectable suspension<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia in adults:\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">40 to 160 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Schizophrenia in adolescents (13\u201317 years old):<\/span><\/p>\n<p><span style=\"font-weight: 400;\">40\u201380 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bipolar depression in adults: 20\u2013120 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bipolar depression in children and adolescents (10\u201317 years old): 20\u201380 mg per day<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia in adults:\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">4 to 8 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Schizophrenia in adolescents (13\u201317 years old):<\/span><\/p>\n<p><span style=\"font-weight: 400;\">3 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bipolar mania in adults: 1\u20136 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bipolar mania in children and adolescents (10\u201317 years old): 1\u20132.5 mg per day<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Autistic disorder:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">0.5 mg per day in those who weigh less than 44 lbs (20 kg) and 1 mg in those who weigh more than 44 lbs (20 kg)<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Short-term or long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Short-term or long-term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults, adolescents, and children 10 years and older, depending on the condition being treated<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults, adolescents, and children 5 years and older, depending on the condition being treated<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h2 id=\"latuda-vs-risperidone-conditions-treated\"><span style=\"font-weight: 400;\">Latuda vs. risperidone: Conditions treated<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone are approved by the Food and Drug Administration (FDA) for the treatment of <\/span><span style=\"font-weight: 400;\">schizophrenia<\/span><span style=\"font-weight: 400;\"> in adults and adolescents 13 years and older. These medications may help treat symptoms like hallucinations, delusions, and disorganized thinking.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Latuda is also used for <\/span><span style=\"font-weight: 400;\">treating bipolar depression<\/span><span style=\"font-weight: 400;\"> in adults and children ages 10 and older. It can be used alone or as an add-on therapy with lithium or valproate. Risperidone, on the other hand, is approved to treat mania associated with bipolar disorder. In addition, risperidone can treat symptoms of irritability in children and adolescents 5 years and older.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-latuda-vs-risperidone-conditions-treated\"><span class=\"title\">Compare Latuda vs. risperidone conditions treated<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Bipolar depression<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Bipolar mania<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Irritability caused by autistic disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h2 id=\"is-risperidone-better-than-latuda\"><span style=\"font-weight: 400;\">Is risperidone better than Latuda?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">An open-label <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7201608\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">extension study<\/span><\/a><span style=\"font-weight: 400;\"> looked at the effects of switching from risperidone to lurasidone in patients with schizophrenia. Both groups showed similar improvements in their symptoms, as measured by the Positive and Negative Syndrome Scale (PANSS). In addition, patients switching to lurasidone showed improved metabolic health, such as a significant drop in prolactin levels.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7497364\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">meta-analysis<\/span><\/a><span style=\"font-weight: 400;\"> of more than 10 clinical trials compared the effectiveness and side effects of lurasidone and risperidone for treating schizophrenia in teenagers. Lurasidone led to significantly less weight gain, with patients gaining around 2.5 lbs (1.16 kg) less than those on risperidone. In addition, the study found that lurasidone had a lower risk of a person stopping treatment than those on other drugs like aripiprazole and paliperidone ER.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The better choice between these treatment options will depend on a person\u2019s overall condition. A healthcare provider can determine the most appropriate medication.\u00a0<\/span><\/p>\n<h2 id=\"latuda-vs-risperidone-insurance-coverage-and-cost-comparison\"><span style=\"font-weight: 400;\">Latuda vs. risperidone: Insurance coverage and cost comparison<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Latuda is a brand-name drug. Therefore, it tends to be on the higher end in cost. Insurance may require <\/span><span style=\"font-weight: 400;\">prior authorization<\/span><span style=\"font-weight: 400;\"> or step therapy, meaning trying cheaper generic drugs like risperidone first. Risperidone is generally covered by most insurance plans and Medicare. Latuda is also available in a generic form, which may be widely available and covered by insurance plans.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Without insurance, the average retail price of Latuda is $1,863 for a 30-day supply of 40 mg tablets. In contrast, risperidone averages $130 for a 30-day supply of 1 mg tablets. Prices fluctuate and can vary significantly based on location and pharmacy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Patients could save on prescription drugs by using  coupons, which offer discounts on medications like <\/span><span style=\"font-weight: 400;\">Latuda<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">risperidone<\/span><span style=\"font-weight: 400;\">. Using these coupons may make a difference in reducing out-of-pocket costs.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-latuda-vs-risperidone-cost-coverage\"><span class=\"title\">Compare Latuda vs. risperidone cost &amp; coverage<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">40 mg (30 tablets)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 mg (30 tablets)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b> cost*<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$22 (for generic lurasidone)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$4<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><span style=\"font-weight: 400;\">*Cost at the time of publication varies by pharmacy.<\/span><\/h5>\n<p><strong>Save on schizophrenia medication<\/strong><\/p>\n<h2 id=\"latuda-vs-risperidone-side-effects\"><span style=\"font-weight: 400;\">Latuda vs. risperidone side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Common side effects of these antipsychotic drugs include drowsiness, insomnia, nausea, and weight gain. Latuda and risperidone may also cause movement disorders like being unable to sit still (akathisia) and involuntary repetitive movements (<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5472076\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">tardive dyskinesia<\/span><\/a><span style=\"font-weight: 400;\">).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Risperidone is more commonly associated with weight gain, insomnia, and anxiety than Latuda. On the other hand, Latuda may more frequently cause nausea and restlessness.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Serious side effects can also occur with both drugs. For example, both drugs may carry a risk of neuroleptic malignant syndrome, a potentially life-threatening condition with symptoms such as muscle rigidity, fever, and altered mental status. These medications may also increase the risk of low blood pressure and seizures.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-latuda-vs-risperidone-side-effects\"><span class=\"title\">Compare Latuda vs. risperidone side effects<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Nausea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Increased saliva production<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Indigestion<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">6%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Constipation<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u2013<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Drowsiness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">17%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Restlessness or feeling unable to stay still\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">13%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Movement problems<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">14%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Runny or stuffy nose<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Weight gain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">7%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Insomnia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">32%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dizziness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Anxiety<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">16%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Blurred vision<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dry mouth<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><i><span style=\"font-weight: 400;\">Frequency is not based on data from a head-to-head trial. This may not be a complete list of adverse effects that can occur. Please refer to your healthcare provider to learn more.<\/span><\/i><\/h5>\n<h5><span style=\"font-weight: 400;\">Source: DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=afad3051-9df2-4c54-9684-e8262a133af8\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Latuda<\/span><\/a><span style=\"font-weight: 400;\">), DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=7e117c7e-02fc-4343-92a1-230061dfc5e0\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Risperdal<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/h5>\n<h2 id=\"latuda-and-risperidone-drug-interactions\"><span style=\"font-weight: 400;\">Latuda and risperidone drug interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone share similar drug interactions. Both Latuda and risperidone affect the central nervous system (CNS). Combining them with other CNS depressants, such as benzodiazepines, opioids, or alcohol, may amplify drowsiness or dizziness.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone may lower blood pressure. If they\u2019re used with <\/span><span style=\"font-weight: 400;\">other medications that lower blood pressure<\/span><span style=\"font-weight: 400;\">, the combined effect can be significant, requiring careful monitoring. Latuda and risperidone may reduce the effectiveness of medications like levodopa and dopamine agonists, which are used to treat Parkinson\u2019s disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain antifungals and antibiotics, such as ketoconazole and clarithromycin, can increase Latuda or risperidone levels in the body. Other drugs can lower Latuda and risperidone levels, making them less effective. Therefore, combining these medications with Latuda or risperidone may need to be avoided or done with caution.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain <\/span><span style=\"font-weight: 400;\">antidepressants<\/span><span style=\"font-weight: 400;\"> like fluoxetine and paroxetine can increase risperidone levels. Dose adjustments may be necessary if these drugs are used together.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-latuda-vs-risperidone-drug-interactions\"><span class=\"title\">Compare Latuda vs. risperidone drug interactions<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Xanax (alprazolam)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Valium (diazepam)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Restoril (temazepam)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Benzodiazepines<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Vicodin (hydrocodone\/acetaminophen)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Percocet (oxycodone\/acetaminophen)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Opioids<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Prinivil, Zestril (lisinopril)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Norvasc (amlodipine)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cozaar (losartan)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lopressor, Toprol-XL (metoprolol)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Microzide (hydrochlorothiazide)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antihypertensives<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Sinemet, Stalevo (levodopa)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mirapex (pramipexole)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Requip (ropinirole)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Levodopa and dopamine agonists<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nizoral (ketoconazole)\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sporanox (itraconazole)\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Diflucan (fluconazole)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antifungal<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Ery-Tab (erythromycin)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Biaxin (clarithromycin)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Rifadin (rifampin)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antibiotic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Norvir (ritonavir)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Reyataz (atazanavir)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antiretroviral<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Tegretol (carbamazepine)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dilantin (phenytoin)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Anticonvulsant<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Prozac (fluoxetine)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Paxil (paroxetine)<\/span><\/p>\n<\/td>\n<td><span style=\"font-weight: 400;\">Antidepressant<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Luminal (phenobarbital)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Barbiturate<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">St. John\u2019s wort<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Herbal<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><i><span style=\"font-weight: 400;\">Consult a healthcare professional for other possible drug interactions.<\/span><\/i><\/h5>\n<h2 id=\"latuda-and-risperidone-drug-warnings\"><span style=\"font-weight: 400;\">Latuda and risperidone drug warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone both have serious warnings, especially for older adults with dementia-related psychosis. These drugs are not approved for these patients due to an increased risk of death.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other warnings for these medications include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Neuroleptic malignant syndrome: <\/b><span style=\"font-weight: 400;\">Both medications also carry a risk of neuroleptic malignant syndrome, a life-threatening condition that requires stopping the medication immediately.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tardive dyskinesia:<\/b><span style=\"font-weight: 400;\"> This serious movement disorder has been reported in those using Latuda and risperidone, which may require stopping the drugs.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Metabolic changes: <\/b><span style=\"font-weight: 400;\">High blood sugar (glucose) levels, increased lipid levels, and weight gain are common with both medications. In addition, both drugs can cause elevated prolactin levels, leading to potential hormonal issues.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Orthostatic hypotension<\/b><span style=\"font-weight: 400;\">: A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7524811\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">sudden drop in blood pressure<\/span><\/a><span style=\"font-weight: 400;\"> when standing can occur with either drug.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Low white blood cell counts: <\/b><span style=\"font-weight: 400;\">Both medications may cause low white blood cell counts.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Problems with thinking and coordination: <\/b><span style=\"font-weight: 400;\">Latuda and risperidone can cause cognitive and motor impairment, so patients should be careful when driving or operating machinery.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Seizures:<\/b><span style=\"font-weight: 400;\"> These medications also increase the <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31681966\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">risk of seizures<\/span><\/a><span style=\"font-weight: 400;\">, especially in those with a history of seizures or conditions that lower the seizure threshold.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Latuda has a specific warning about increasing suicidal thoughts and behaviors in young people. Close monitoring for any signs of worsening depression or suicidal thoughts is important.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Latuda and risperidone require careful monitoring by a healthcare provider to manage and reduce potential side effects. Always consult a healthcare provider for medical advice if you experience adverse effects while taking these medications.<\/span><\/p>\n<h2 id=\"can-you-take-latuda-and-risperidone-together\"><span style=\"font-weight: 400;\">Can you take Latuda and risperidone together?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Taking Latuda and risperidone together is generally not recommended because they both work as antipsychotics and can lead to an increased risk of side effects. These side effects can include severe drowsiness, dizziness, weight gain, and metabolic changes. 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<\/g>\n<\/svg>\t\t\t\t\t\t\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do you know: Differences, similarities &#038; side effects in 2025 Key takeaways Latuda and risperidone are atypical antipsychotics used to treat schizophrenia and bipolar disorder. Latuda is taken once daily and treats both schizophrenia and bipolar depression, while risperidone can be taken once or twice daily and treats schizophrenia, bipolar mania, and irritability in autism. 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